Patents by Inventor Wei-Chuan Sun
Wei-Chuan Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240167640Abstract: A light-emitting unit, having a substrate; a first light-emitting body formed on the substrate, and having a first longer side and a first shorter side; a second light-emitting body formed on the substrate, and having a second longer side and a second shorter side which is parallel to the first longer side; a third light-emitting body formed on the substrate, having a third longer side and a third shorter side which is parallel to the first longer side, and electrically connected to the first light-emitting body and the second light-emitting body; a first electrode covering the first light-emitting body and the second light-emitting body, and electrically connecting to the first light-emitting body; a second electrode separated from the first electrode, and covering the second light-emitting body without covering the first light-emitting body; and a transparent element enclosing the first light-emitting body, the second light-emitting body, and the third light-emitting body.Type: ApplicationFiled: December 26, 2023Publication date: May 23, 2024Inventors: Wei-Chiang HU, Keng-Chuan CHANG, Chiu-Lin YAO, Chun-Wei LIN, Jung-Chang SUN
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Patent number: 11972537Abstract: A method for flattening a three-dimensional shoe upper template is provided. The method includes providing a three-dimensional last model, obtaining a three-dimensional grid model, obtaining a three-dimensional thickened grid model, obtaining a two-dimensional initial-value grid model, and obtaining a two-dimensional grid model with the smallest energy value. A system and a non-transitory computer-readable medium for performing the method are also provided. The method makes it possible to precisely flatten a three-dimensional last model with a non-developable surface and thereby convert the three-dimensional last model into a two-dimensional grid model.Type: GrantFiled: August 19, 2022Date of Patent: April 30, 2024Assignee: YU JUNG CHANG TECHNOLOGY CO., LTD.Inventors: Chih-Chuan Chen, Wei-Hsiang Tsai, Chin-Yu Chen, Ching-Cherng Sun, Jann-Long Chern, Yu-Kai Lin
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Patent number: 10458915Abstract: The present invention provides heteroaryl functionalized cyanine dyes including a reactive functional moiety, or which are conjugated to a carrier molecule.Type: GrantFiled: May 20, 2013Date of Patent: October 29, 2019Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Yue, Gene Shen, Wei-Chuan Sun
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Patent number: 9702001Abstract: The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates.Type: GrantFiled: November 3, 2014Date of Patent: July 11, 2017Assignee: Pacific Biosciences of California, Inc.Inventors: Gene Shen, Lubomir Sebo, Stephen Yue, Wei-Chuan Sun, Louis Brogley, Andrei Fedorov
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Patent number: 9637782Abstract: Mitigation of photo-induced damage in excitation illuminated reactions and analyses utilizing such reactions results in an enhanced performance for the reactions and the analyses. There is provided a novel class of triplet-state quenchers for mitigating photo-induced damage which are both simple in structure and effective at preventing and/or reducing photo-induced damage to reaction components of excitation illuminated reaction mixtures. Also provided are methods of using the compounds of the invention, devices and kits incorporating the compounds of the invention.Type: GrantFiled: September 27, 2013Date of Patent: May 2, 2017Assignee: Pacific Biosciences of California, Inc.Inventors: Gene Shen, Andrei Fedorov, Wei-Chuan Sun, Stephen Yue
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Patent number: 9386938Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.Type: GrantFiled: September 12, 2011Date of Patent: July 12, 2016Assignee: Collagen Medical, LLCInventors: Peter D. Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Kumar Das, Vincent Jacques, Richard Looby, Steffi K. Koerner, Wei-Chuan Sun, David R. Buckler, Aida Abujoub, Aaron K. Sato
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Patent number: 9315864Abstract: Heteroaryl cyanine dyes bearing sulfonic acid substituents are of use in various assays, including single molecule nucleic acid sequencing. Exemplary heteroaryl cyanines dyes include or more reactive functional group, which is of use to covalently conjugate the cyanine dye to a carrier molecule. An exemplary carrier molecule is an analyte molecule or other molecule of interest, for example, a nucleotide oligophosphate.Type: GrantFiled: November 20, 2013Date of Patent: April 19, 2016Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Yue, Gene Shen, Wei-Chuan Sun
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Publication number: 20150307933Abstract: The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates.Type: ApplicationFiled: November 3, 2014Publication date: October 29, 2015Inventors: Gene Shen, Lubomir Sebo, Stephen Yue, Wei-Chuan Sun, Louis Brogley, Anderi Fedorov
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Patent number: 8906612Abstract: The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates.Type: GrantFiled: August 25, 2011Date of Patent: December 9, 2014Assignee: Pacific Biosciences of California, Inc.Inventors: Gene Shen, Lubomir Sebo, Stephen Yue, Wei-Chuan Sun, Louis Brogley, Andrei Fedorov
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Publication number: 20140093935Abstract: Mitigation of photo-induced damage in excitation illuminated reactions and analyses utilizing such reactions results in an enhanced performance for the reactions and the analyses. There is provided a novel class of triplet-state quenchers for mitigating photo-induced damage which are both simple in structure and effective at preventing and/or reducing photo-induced damage to reaction components of excitation illuminated reaction mixtures. Also provided are methods of using the compounds of the invention, devices and kits incorporating the compounds of the invention.Type: ApplicationFiled: September 27, 2013Publication date: April 3, 2014Applicant: Pacific Biosciences of California, Inc.Inventors: Gene Shen, Andrei Fedorov, Wei-Chuan Sun, Stephen Yue
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Publication number: 20140080127Abstract: The present invention provides heteroaryl functionalized cyanine dyes including a reactive functional moiety, or which are conjugated to a carrier molecule.Type: ApplicationFiled: November 20, 2013Publication date: March 20, 2014Applicant: Pacific Biosciences of California, Inc.Inventors: Stephen YUE, Gene Shen, Wei-Chuan Sun
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Publication number: 20140005404Abstract: The present invention provides heteroaryl functionalized cyanine dyes including a reactive functional moiety, or which are conjugated to a carrier molecule.Type: ApplicationFiled: May 20, 2013Publication date: January 2, 2014Applicant: Pacific Biosciences of California, Inc.Inventors: Stephen Yue, Gene Shen, Wei-Chuan Sun
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Patent number: 8338565Abstract: Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.Type: GrantFiled: August 20, 2009Date of Patent: December 25, 2012Assignee: Ensemble Therapeutics CorporationInventors: Jinbo Lee, Julian F. Bond, Nicholas Terrett, Frank G. Favaloro, Jr., Daniel Wang, Timothy F. Briggs, Benjamin Adam Seigal, Wei-Chuan Sun, Stephen P. Hale
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Publication number: 20120114557Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.Type: ApplicationFiled: September 12, 2011Publication date: May 10, 2012Applicant: COLLAGEN MEDICAL, LLCInventors: Peter D. Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Kumar Das, Vincent Jacques, Richard Looby, Steffi K. Koerner, Wei-Chuan Sun, David R. Buckler, Aida Abujoub, Aaron K. Sato
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Publication number: 20120077189Abstract: The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates.Type: ApplicationFiled: August 25, 2011Publication date: March 29, 2012Applicant: Pacific Biosciences of California, Inc.Inventors: Gene Shen, Lubomir Sebo, Stephen Yue, Wei-Chuan Sun, Louis Brogley, Andrei Fedorov
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Patent number: 8034898Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.Type: GrantFiled: December 29, 2006Date of Patent: October 11, 2011Assignee: Collagen Medical, LLCInventors: Peter D. Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Kumar Das, Vincent Jacques, Richard Looby, Steffi K. Koerner, Wei-Chuan Sun, David R. Buckler, Aida Abujoub, Aaron K. Sato
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Publication number: 20100159446Abstract: The invention provides compositions and methods for the detection and/or quantification of biological targets (e.g., nucleic acids and proteins) by the nucleic acid-templated creation of one or more reaction products, for example, epitopes, enzyme substrates, enzyme activators, and ligands. The reaction products can be detected and/or quantitated after signal amplification using an amplification system.Type: ApplicationFiled: July 21, 2008Publication date: June 24, 2010Inventors: Lawrence A. Haff, Yumei Huang, Richard A. Martinelli, Benjamin A. Seigal, David J. Livingston, Wei-Chuan Sun
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Publication number: 20100152099Abstract: The invention provides macrocyclic compounds and methods for their synthesis and use. In particular, the invention provides macrocyclic compounds that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.Type: ApplicationFiled: August 20, 2009Publication date: June 17, 2010Inventors: Jinbo Lee, Julian F. Bond, Nicholas Terrett, Frank G. Favaloro, JR., Daniel Wang, Timothy F. Briggs, Benjamin A. Seigal, Wei-Chuan Sun, Stephen P. Hale
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Publication number: 20080058636Abstract: Diagnostic compositions and methods for imaging collagen and/or assessing myocardial perfusion are described. The diagnostic compositions can include collagen binding peptides.Type: ApplicationFiled: December 29, 2006Publication date: March 6, 2008Inventors: Peter Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Das, Vincent Jacques, Richard Looby, Steffi Koerner, Wei-Chuan Sun, David Buckler, Aida Abujoub, Aaron Sato
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Publication number: 20080044360Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.Type: ApplicationFiled: December 29, 2006Publication date: February 21, 2008Inventors: Peter Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Das, Vincent Jacques, Richard Looby, Steffi Koerner, Wei-Chuan Sun, David Buckler, Aida Abujoub, Aaron Sato