Patents by Inventor Weiliang Zhu

Weiliang Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240144869
    Abstract: This application discloses a power supply circuit, a driving apparatus, and a display apparatus, and relates to the field of display technologies. The power supply circuit includes: a first power supply module and a second power supply module. An output end of the first power supply module is connected to a first output end of the second power supply module, and is configured to be connected to a first input end of the driving module. An output end of the first power supply module is configured to output a first voltage signal, and a first output end of the second power supply module is configured to output a second voltage signal. A second output end of the second power supply module is configured to be connected to a second input end of the driving module, so as to output a third voltage signal.
    Type: Application
    Filed: January 13, 2022
    Publication date: May 2, 2024
    Inventors: Bowen Li, Weiliang Duan, Yan Li, Chen Zhu
  • Publication number: 20230338510
    Abstract: Provided are a tandem epitope polypeptide vaccine for novel coronavirus and use thereof. Specifically, a vaccine polypeptide for novel coronavirus pneumonia is provided on the basis of analysis and study of the RBD sequence and structural information of the S protein of SARS-CoV-2. Said vaccine polypeptide comprises the following elements connected in series: a generic Th epitope sequence, a B cell epitope sequence and a T cell epitope sequence. The B cell epitope and the T cell epitope have an amino acid sequence from the RBM region of the S protein of SARS-CoV-2. Provided are a vaccine composition containing said vaccine polypeptide and use thereof. Experiments show that the vaccine polypeptide of the present invention can enable cynomolgus monkeys to initiate strong cellular and humoral immunity, and to generate neutralizing antibodies that block the binding of RBD and ACE2, and can be used for preventing and treating novel coronavirus pneumonia.
    Type: Application
    Filed: June 11, 2021
    Publication date: October 26, 2023
    Inventors: Likun GONG, Jin REN, Qiuping QIN, Weiliang ZHU, Yiru LONG, Zhijian XU, Jianhua SUN, Tingting LIU, Guangyi JIN, Jianping ZUO, Wei HUANG
  • Publication number: 20220177515
    Abstract: The present disclosure relates to a method for modifying or marking an amino group in a molecule, wherein the amino group in the molecule is modified or marked with zolinium(s) shown in the following formula 1, wherein the molecule comprises amino acid ester, aminoamide, or peptide/protein. The method has advantages of economy and site selectivity, and has huge potential application value in the field such as pharmaceutical molecular synthesis, probe molecule and diagnostic marker reagent development.
    Type: Application
    Filed: March 30, 2020
    Publication date: June 9, 2022
    Inventors: Bo LI, Peng LIU, Haiguo SUN, Mengyu XI, Zhijian XU, Yong ZHANG, Weiliang ZHU
  • Patent number: 10966996
    Abstract: Disclosed is a Glechoma longituba (Nakai) Kupr. extract, specifically compounds I and II, a preparation method for same, and a use thereof in preparing a medicament for blood glucose decease, blood lipids decrease, weight loss, and kidney disease treatment or a method for treatment of said diseases, and a composition containing the extract.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: April 6, 2021
    Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES, NANJING PAILEXING PHARMACEUTICAL TECHNOLOGY LTD.
    Inventors: Weiliang Zhu, Heyao Wang, Yong Zhang, Peng Sun, Bo Li, Zhijian Xu, Hualiang Jiang, Kaixian Chen
  • Publication number: 20170087173
    Abstract: Disclosed is a Glechoma longituba (Nakai) Kupr. extract, specifically compounds I and II, a preparation method for same, and a use thereof in preparing a medicament for blood glucose decease, blood lipids decrease, weight loss, and kidney disease treatment or a method for treatment of said diseases, and a composition containing the extract.
    Type: Application
    Filed: March 17, 2015
    Publication date: March 30, 2017
    Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES, NANJING PAILEXING PHARMACEUTICAL TECHNOLOGY LTD.
    Inventors: Weiliang ZHU, Heyao WANG, Yong ZHANG, Peng SUN, Bo LI, Zhijian XU, Hualiang JIANG, Kaixian CHEN
  • Patent number: 9527849
    Abstract: The present invention relates to new salts of pyrazolopyrimidinone represented by formula (I), and pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystallization, anhydrous, or amorphous form thereof, the pharmaceutical compositions, and a pharmaceutical unit dosage form containing the same, wherein x represents organic or inorganic acids, preferable maleic acid, succinic acid, methanesulfonic acid, hydrochloric acid, etc. The invention further relates to co-crystals or complexes of compounds of pyrazolopyrimidinone and pharmaceutical compositions containing the same. The present invention also relates to a process for the preparation, use thereof and pharmaceutical preparation containing the salts or crystalline forms.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: December 27, 2016
    Assignees: TOPHARMAN SHANGHAI CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES TOPHARMAN SHANDONG CO., LTD
    Inventors: Jianfeng Li, Guanghui Tian, Zhen Wang, Jin Suo, Xiangrui Jiang, Zheng Liu, Xiaojun Yang, Zhu Xie, Xianguo Zhao, Weiliang Zhu, Hualiang Jiang, Jingshan Shen
  • Patent number: 8871777
    Abstract: The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the pharmaceutically acceptable salts or solvates thereof and to the pharmaceutical composition as well as the preparation method of the compounds. The compounds of formula I according to the present invention can effectively inhibit type V phosphodiesterase (PDE5), and thus can be used for the treatment of various vascular disorders, such as male erectile dysfunction, pulmonary hypertension and the like.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: October 28, 2014
    Assignees: Topharman Shanghai Co., Ltd., Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Topharman Shandong Co., Ltd.
    Inventors: Zheng Liu, Jianfeng Li, Xiaojun Yang, Zhen Wang, Jinfeng Zhang, Yi Zhu, Guanghui Tian, Qing Jin, Jingkang Shen, Weiliang Zhu, Hualiang Jiang, Jingshan Shen
  • Publication number: 20130163873
    Abstract: A system and method of detecting separator lines in a web page may include determining coordinates of visible web elements on a web page, generating an edge image of the web page based on the coordinates of the web elements, filtering edges belonging to non-separator line elements within the edge image, detecting horizontal lines within the edge image, detecting vertical lines within the edge image, and filtering short lines within the edge image. A system for detecting separator lines in a web page may include a memory device, and a processor communicatively coupled to the memory, in which the processor determines coordinates of visible web elements on a web page, generates an edge image of the web page based on the coordinates of the web elements, filters edges belonging to non-separator line elements within the edge image, detects horizontal lines within the edge image, detects vertical lines within the edge image, and filters short lines within the edge image.
    Type: Application
    Filed: July 30, 2010
    Publication date: June 27, 2013
    Inventors: Zhao Qingjie, Jianfeng Li, Ruisheng Xiong, Jingshan Shen, Weiliang Zhu, Hualiang Jiang, Jingkang Shen, Kyoung Tai No, Han Jo Kim, Ky-Youb Nam, Baik Lin Seong, Woo Jin Shin
  • Publication number: 20110301109
    Abstract: The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the pharmaceutically acceptable salts or solvates thereof and to the pharmaceutical composition as well as the preparation method of the compounds. The compounds of formula I according to the present invention can effectively inhibit type V phosphodiesterase (PDE5), and thus can be used for the treatment of various vascular disorders, such as male erectile dysfunction, pulmonary hypertension and the like.
    Type: Application
    Filed: December 10, 2009
    Publication date: December 8, 2011
    Applicants: TOPHARMAN SHANGHAI CO., LTD.
    Inventors: Zheng Liu, Jianfeng Li, Xiaojun Yang, Zhen Wang, Jinfeng Zhang, Yi Zhu, Guanghui Tian, Qing Jin, Jingkang Shen, Weiliang Zhu, Hualiang Jiang, Jingshan Shen
  • Publication number: 20090182133
    Abstract: The invention relates to pharmaceutical compositions comprising benzopyranone derivatives for the treatment of Severe Acute Respiratory Syndrome (SARS).
    Type: Application
    Filed: December 15, 2006
    Publication date: July 16, 2009
    Inventors: Chum Mok Puah, Weiliang Zhu, Jian Li, Lili Chen, Cheng Luo, Gang Chen, Zhili Zuo, Xiaomin Luo, Xu Shen, Kaixian Chen, Hualiang Jiang
  • Patent number: 7529303
    Abstract: Methods and apparatus are provided for determining transmission power levels. The power characteristics of a cable modem family are determined by testing cable modems in a cable modem family with various downstream frequencies and transmission power levels to determine internal gain levels. The power characteristics of the cable modem family can then be stored in an efficient manner in each cable modem by using interpolation. The individual cable modem can then be characterized by testing the cable modem with a limited set of downstream frequencies and transmission power levels to determine an internal gain level offset for that particular cable modem. With the power characteristics table, internal gain level offset, and interpolation, transmission power levels can be determined during network operation when downstream frequencies and internal gain levels are known.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: May 5, 2009
    Assignee: Cisco Technology, Inc.
    Inventors: Alejandro Schwartzman, Paul Lafferty, Weiliang Zhu, Timothy Finan
  • Patent number: 7221712
    Abstract: Methods and apparatus are provided for determining transmission power levels. The power characteristics of a cable modem family are determined by testing cable modems in a cable modem family with various downstream frequencies and transmission power levels to determine internal gain levels. The power characteristics of the cable modem family can then be stored in an efficient manner in each cable modem by using interpolation. The individual cable modem can then be characterized by testing the cable modem with a limited set of downstream frequencies and transmission power levels to determine an internal gain level offset for that particular cable modem. With the power characteristics table, internal gain level offset, and interpolation, transmission power levels can be determined during network operation when downstream frequencies and internal gain levels are known.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: May 22, 2007
    Assignee: Cisco Technology, Inc.
    Inventors: Alejandro Schwartzman, Paul Lafferty, Weiliang Zhu, Timothy Finan