Abstract: A flip-chip light-emitting device includes a transparent substrate, an epitaxial structure, a transparent dielectric layer, a plurality of first contact electrodes, multiple second contact electrodes, a metallic reflection layer, a first insulating layer, and an electrode pad region. The epitaxial structure is formed on the transparent substrate, and includes a first type semiconductor layer, an active layer, and a second type semiconductor layer. The first and second contact electrodes are embedded in the transparent dielectric layer, and respectively connected to the first and second type semiconductor layers. The second and first contact electrodes are arranged in an array. The second contact electrodes are disposed in a region perpendicularly below the first pad and are distributed along a circular ring that is concentric with one of the first contact electrodes. A light emitting module includes a circuit board, and the flip-chip light emitting device is mounted on the circuit board.

Abstract: The light-emitting device includes a substrate, a light-emitting chip unit formed on the substrate and including multiple chips, an isolation groove extending in a first direction and separating two adjacent ones of the chips, and a bridging structure. The isolation groove is defined by a bottom and two sidewalls and has a first groove section and a second groove section arranged in the first direction. The first groove section has a width in a width direction perpendicular to the first direction that is greater than a width of the second groove section in the width direction. At the first groove section, one of the sidewalls has a curved portion. The bridging structure is formed on the bottom and the sidewalls, covers the curved portion, and electrically connects the two adjacent ones of the chips.

Abstract: A discovery of the conversion of amorphous calcium polyphosphate (ACPP) or/and other polyphosphate salts with various type of calcium phosphate to new calcium phosphate product (i.e. dicalcium phosphate dihydrate (DCPD)) in a liquid environment. The discovery includes mixing a various type of calcium phosphate with an aqueous ACPP or/and other polyphosphate salts gel, which is fast setting and possessing strong mechanical strength, and can be gradually converted to DCPD/hydroxyapatites in physiological condition. This injectable past can be applied as alternative of conventional CPC bone cement that is suitable for bone void repair due to its excellent properties in osteoconductivity and osseointegration. It can also be applied as drug delivery device in tissue engineering for its strong bonding to drug molecules.

Abstract: The present invention describes an injectable calcium polyphosphate (CPP) gel with dense structure, which can be applied as injectable bone void filler in medical field, such as orthopedic and dental applications. Amorphous CPP powder with fine particle size (<75 pm) can be completely dissolved in water, forming a homogeneous gelation phase separated from water phase. This homogeneous CPP gel with disentangled inorganic polyphosphate chains shows viscoelasticity and superior adhesion to natural bone, metal implant surfaces and other ceramic material surfaces. The CPP gel is biomimetic and biodegradable with strong osteoconductivity and osteoinductivity. The manufacturing procedure is easy and reproducible. The mechanical strength of CPP gel is controllable by modifications, such as sintering, incorporation of other biomaterials, etc.

Abstract: A discovery of the conversion of amorphous calcium polyphosphate (ACPP) or/and other polyphosphate salts with various type of calcium phosphate to new calcium phosphate product (i.e. dicalcium phosphate dihydrate (DCPD)) in a liquid environment. The discovery includes mixing a various type of calcium phosphate with an aqueous ACPP or/and other polyphosphate salts gel, which is fast setting and possessing strong mechanical strength, and can be gradually converted to DCPD/hydroxyapatites in physiological condition. This injectable past can be applied as alternative of conventional CPC bone cement that is suitable for bone void repair due to its excellent properties in osteoconductivity and osseointegration. It can also be applied as drug delivery device in tissue engineering for its strong bonding to drug molecules.

Abstract: The present invention relates to a device for preparing three dimensional (3D) nanofibers (blended or coaxial) materials by electrospinning. An automatic nanofiber collector device is used to control the porosity, pore size, crystallinity, geometry, the layer number and thickness of formed nanofibers. The automatic nanofiber collector device includes: (1) a collector platform; (2) a non-conductive device used to fix the collector device; (3) a plurality of electro-conductive wires or needles being pierced through the collector platform with various heights, and (4) the ends of the needles (at bottom) are wired and controlled by a microcontroller, providing forward, stand and backward movements for attached needles. The desired 3D nanofiber scaffold structures can be tailored by the micro-stepping programmable motor controller by changing the pattern and velocity of needle movement, generalized or selective needles movements, as well as intermittent versus continuous movement.

Abstract: The present invention provides a fingerstall-cannulated guide device for accurate and efficient guide wire placement for antegrade femoral nailing systems. The said device comprises a fingerstall with a cannulated guide connected with or without a threaded guide wire. Using this device, surgeons can determine the entry point for the guide wire fast and accurately by tactile hand-eye coordination. After correct entry point is obtained, the guide wire is advanced and the fingerstall-cannulated guide can be easily detached. The device and method can accomplish the following: (1) reduction of the surgery time; (2) reduction of the radiation exposure times, and (3) reduction of the soft tissue damage during surgery. The device is also beneficial for use in fastening together any or all portions of bone surrounding a fracture site.

Abstract: The present invention describes an injectable calcium polyphosphate (CPP) gel with dense structure, which can be applied as injectable bone void filler in medical field, such as orthopedic and dental applications. Amorphous CPP powder with fine particle size (<75 pm) can be completely dissolved in water, forming a homogeneous gelation phase separated from water phase. This homogeneous CPP gel with disentangled inorganic polyphosphate chains shows viscoelasticity and superior adhesion to natural bone, metal implant surfaces and other ceramic material surfaces. The CPP gel is biomimetic and biodegradable with strong osteoconductivity and osteoinductivity. The manufacturing procedure is easy and reproducible. The mechanical strength of CPP gel is controllable by modifications, such as sintering, incorporation of other biomaterials, etc.

Abstract: The present invention provides a disposable tube that represents a low-cost and convenient container for the liquid aliquots of biological and immunological reagents, such as monoclonal antibodies, purified enzymes, for use in the determination of various components from biological sources. The disposable tube is composed of plastic material with sealed liquid aliquots inside. This tube can be opened by the rupture of both sealed ends right before use. The present invention relates to a new “ready for use” tube and relevant kit(s) that can be used in various kind of biochemical, immunological analysis including, but not limited to, immunohistochemical and immunocytochemical staining, immunoprecipitation, western blot, enzyme activity analysis, in the determination of various components from biological sources. A relevant prototype of “Leukocyte Immunophenotyping Kit” is also described.