Patents by Inventor Weiqin Jiang

Weiqin Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 9434688
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: September 6, 2016
    Assignee: Janssen Pharmaceutica NV
    Inventors: James C Lanter, Zhihua Sui, James J Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20140249197
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: May 14, 2014
    Publication date: September 4, 2014
    Applicant: Janssen Pharmaceutica, NV
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 8765782
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: July 1, 2014
    Assignee: Janssen Pharmaceutica, NV
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 8394971
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: March 12, 2013
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20110021785
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: January 20, 2010
    Publication date: January 27, 2011
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20100144823
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: February 17, 2010
    Publication date: June 10, 2010
    Inventors: James C. Lantar, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 7705147
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: April 27, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • 11-phosphorous steroid derivatives useful as progesterone receptor modulators
    Patent number: 7678781
    Abstract: The present invention is directed to novel 11-phosphorous steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by a progesterone or glucocorticoid receptor.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: March 16, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James J. Fiordeliso, Weiqin Jiang, Zhihua Sui
  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 7678926
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: March 16, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • 17-phosphorous steroid derivatives useful as progesterone receptor modulators
    Patent number: 7671045
    Abstract: The present invention is directed to novel 17-phosphorous steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by a progesterone or glucocorticoid receptor.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: March 2, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Weiqin Jiang, Zhihua Sui
  • Pyridine Imidazoles and Aza-indoles as Progesterone Receptor Modulators
    Publication number: 20100016266
    Abstract: The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatment of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.
    Type: Application
    Filed: September 14, 2009
    Publication date: January 21, 2010
    Inventors: Weiqin Jiang, James J. Flordeliso, Zhihua Sui
  • Trisubstituted thiophenes as progesterone receptor modulators
    Patent number: 7638525
    Abstract: The present invention is directed to novel trisubstituted thiophene derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical usage of these compounds are related to hormonal contraception, the treatment and/or prevention of secondary dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon or prostate. Additional uses of the invention include stimulation of food intake.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: December 29, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui
  • Trisubstituted Thiophenes as Progesterone Receptor Modulators
    Publication number: 20090306118
    Abstract: The present invention is directed to novel trisubstituted thiophene derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical usage of these compounds are related to hormonal contraception, the treatment and/or prevention of secondary dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon or prostate. Additional uses of the invention include stimulation of food intake.
    Type: Application
    Filed: August 17, 2009
    Publication date: December 10, 2009
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui
  • Pyridine imidazoles and aza-indoles as progesterone receptor modulators
    Patent number: 7608712
    Abstract: The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatment of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: October 27, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui
  • NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20090216023
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: August 8, 2008
    Publication date: August 27, 2009
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 7427682
    Abstract: The present invention is directed to novel insole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: September 23, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • PYRIDINE IMIDAZOLES AND AZA-INDOLES AS PROGESTERONE RECEPTOR MODULATORS
    Publication number: 20080119500
    Abstract: The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatment of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.
    Type: Application
    Filed: February 1, 2008
    Publication date: May 22, 2008
    Inventors: Weiqin Jiang, James Fiordeliso, Zhihua Sui
  • Pyridine imidazoles and aza-indoles as progesterone receptor modulators
    Patent number: 7348432
    Abstract: The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatment of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: March 25, 2008
    Assignee: Janssen Phamaceutica N.V.
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui
  • NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20080070970
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: September 20, 2007
    Publication date: March 20, 2008
    Inventors: James Lanter, Zhihua Sui, James Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Indole derivatives useful as progesterone receptor modulators
    Patent number: 7345084
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding. Additional uses of the invention include stimulation of food intake.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: March 18, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui