Patents by Inventor Weiwei Su

Weiwei Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240118157
    Abstract: An ambient pressure compensation structure for an ultraviolet difference spectrum gas sensor includes a closed box, an ultraviolet difference spectrum gas sensor, a digital pressure sensor, a thermostatic controller, an industrial control computer, a pressure regulating assembly and a limiting partition; the pressure regulating assembly and the limiting partition are arranged inside the closed box, the pressure regulating assembly comprises a piston, a regulating rod and a driving motor, the left side of the piston is connected with the regulating rod, the front end of the regulating rod penetrates out of the closed box and is connected with the driving motor, and the piston divides the interior of the closed box into a pressure regulating air chamber and a working air chamber. Also disclosed is an ambient pressure compensation method for an ultraviolet difference spectrum gas sensor.
    Type: Application
    Filed: December 19, 2023
    Publication date: April 11, 2024
    Inventors: Fuchao TIAN, Yuntao LIANG, Shuanglin SONG, Xing AI, Yazhou XU, Weiwei SU, Baolong GUO, Zhenrong LI
  • Publication number: 20240083137
    Abstract: Embodiments of this application provide a composite structure including a substrate layer and a functional layer disposed on a surface of at least one side of the substrate layer. The substrate layer includes a first support member and a second support member that are disposed side by side and a bendable connecting member connected to and disposed between the first support member and the second support member. A material of the first support member and the second support member includes a hard rubber fiber composite material, and the functional layer includes one or more of an electrically conductive layer, a thermally conductive layer, or an impact-resistant layer.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Inventors: Yuan QIN, Yangyang LI, Chun ZOU, Weiwei YAO, Nanjian SUN, Taimeng CHEN, Zhaoliang SU
  • Patent number: 11793849
    Abstract: Disclosed is a new drug application of a Pithecellobium Clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter Baumannii (MDRAB), an MDR Pseudomonas Aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia Coli (ECO) and an ESBL-producing Klebsiella Pneumonia (KPN).
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: October 24, 2023
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Patent number: 11654174
    Abstract: Disclosed is a new drug application of a Pithecellobium clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter baumannii (MDRAB), an MDR Pseudomonas aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (ECO) and an ESBL-producing Klebsiella pneumonia (KPN).
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: May 23, 2023
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20230110326
    Abstract: The present invention discloses a solution formulation for aerosol inhalation of naringenin and preparation method thereof. The formulation is prepared from 1 part by weight of naringenin, 15-30 parts by weight of hydroxypropyl ?-cyclodextrin, a buffer-salt solution and an appropriate amount of an excipient. The preparation method includes: preparing a buffer-salt solution of a pH value of 7-8.5 by using the buffer salt, adding the naringenin into the buffer-salt solution, then adding the hydroxypropyl P-cyclodextrin, shaking in a constant-temperature air bath till complete dissolving and coating, adding an appropriate amount of the excipient, filtering, filling and sterilizing. The present invention, by firstly increasing the solubility of the free naringenin in the solvent by adjusting the pH value, and then coating the naringenin with the hydroxypropyl ?-cyclodextrin, significantly increases the overall concentration of the naringenin in the solvent.
    Type: Application
    Filed: August 28, 2019
    Publication date: April 13, 2023
    Inventors: Mingyi GUAN, Weiwei SU, Hongliang YAO
  • Publication number: 20230076197
    Abstract: An application of HJT aqueous extract in the preparation of drugs against a Blue-ear disease is provided. For the first time, it is found in the present invention that HJT extract has a significant effect of preventing and treating the Blue-ear disease. Specifically, through experiments of qRT-PCR and immunofluorescence techniques, the present invention has proved that HJT extract can significantly inhibit infection and replication of PPRSV with significant antiviral effect, so that it is expected to become a new type of biologically active substance for prevention and treatment of Blue-ear disease. The product prepared by the method can be used as natural antiviral drugs for the prevention and treatment of the Blue-ear disease, realizes the comprehensive utilization of HJT plants, and improves its value, which has a good application prospect.
    Type: Application
    Filed: October 10, 2022
    Publication date: March 9, 2023
    Applicant: SUN YAT-SEN UNIVERSITY
    Inventors: Weiwei SU, Yonggang WANG, Peibo LI, Hongyu RAO, Hao WU
  • Publication number: 20220362186
    Abstract: The present invention relates to new medicine application of p-hydroxyphenylpropionic acid. Experiments prove that p-hydroxyphenylpropionic acid has a remarkable pharmacological effect in inhibiting respiratory tract infection, particularly inhibiting pulmonary edema, inflammatory cell infiltration and cell apoptosis in lung injury and delaying lung function degradation of mice. Therefore, the present invention discloses the application of p-hydroxyphenylpropionic acid to prepare a medicine for preventing and treating respiratory tract infection, particularly pneumonia, pulmonary edema or pulmonary epithelial and/or endothelial cell necrosis in lung injury for the first time.
    Type: Application
    Filed: February 1, 2020
    Publication date: November 17, 2022
    Inventors: Hao WU, Taobin CHEN, Yonggang WANG, Weiwei SU
  • Patent number: 11499163
    Abstract: The disclosure relates to an expression method of a Haemocoagulase Acutus (Halase) recombinant protein. The method includes the following steps: (1) optimizing a halase gene; (2) performing Polymerase Chain Reaction (PCR) amplification on an optimized halase gene; (3) constructing an Agkis-pMCX expression vector, transforming plasmids to competent cells of an Escherichia coli for amplification, screening in an Amp-resistant manner for positive cloning, sequencing and extracting recombinant plasmids with correct sequencing; (4) transfecting recombinant plasmids to CHO cells; and (5) expressing the recombinant protein and identifying. According to the expression method, a recombinant halase is expressed first using the CHO cells cultured in a serum-free suspension manner; and by utilizing a bioengineering means, the actual production problems of insufficient raw material sources and unstable quality of a snake venom product are solved successfully.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: November 15, 2022
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Qin Deng, Xiao Shen, Weiwei Su, Zhong Wu, Wei Peng, Yonggang Wang
  • Patent number: 11491198
    Abstract: Disclosed is a new drug application of a Pithecellobium clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter baumannii (MDRAB), an MDR Pseudomonas aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (ECO) and an ESBL-producing Klebsiella pneumonia (KPN).
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: November 8, 2022
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20220031789
    Abstract: Disclosed is a new drug application of a Pithecellobium Clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter Baumannii (MDRAB), an MDR Pseudomonas Aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia Coli (ECO) and an ESBL-producing Klebsiella Pneumonia (KPN).
    Type: Application
    Filed: October 6, 2021
    Publication date: February 3, 2022
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20220023369
    Abstract: Disclosed is a new drug application of a Pithecellobium clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter baumannii (MDRAB), an MDR Pseudomonas aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (ECO) and an ESBL-producing Klebsiella pneumonia (KPN).
    Type: Application
    Filed: October 6, 2021
    Publication date: January 27, 2022
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20210329893
    Abstract: The present disclosure relates to a method for establishing an oral ulcer animal model with Yin-deficiency and fire-excess syndrome based on sleep deprivation, comprising the following steps of: burning buccal mucosa of a rat with phenol to cause a white injury, and obtaining the oral ulcer animal model after 24-48 h; placing the animal model in a sleep deprivation device for 2-7 days; wherein the device is composed of a mouse box in which a plurality of platforms with a diameter of 4-8 cm are arranged at an interval of 10-20 cm from each other; and water is filled among the platforms, and the platforms are about 0.1-2 cm higher than a water surface. The present disclosure overcomes the defects of single evaluation index, short model duration, and unconformity of etiology and clinic existed in the prior art.
    Type: Application
    Filed: April 29, 2019
    Publication date: October 28, 2021
    Applicant: Sun YAT-SEN University
    Inventors: Hongliang YAO, Pan SHEN, Peibo LI, Weiwei SU
  • Patent number: 11154582
    Abstract: Disclosed is a new drug application of a Pithecellobium Clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter Baumannii (MDRAB), an MDR Pseudomonas Aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia Coli (ECO) and an ESBL-producing Klebsiella Pneumonia (KPN).
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: October 26, 2021
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20210106641
    Abstract: Disclosed is a new drug application of a Pithecellobium clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter baumannii (MDRAB), an MDR Pseudomonas aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (ECO) and an ESBL-producing Klebsiella pneumonia (KPN).
    Type: Application
    Filed: December 21, 2020
    Publication date: April 15, 2021
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20210106639
    Abstract: Disclosed is a new drug application of a Pithecellobium clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter baumannii (MDRAB), an MDR Pseudomonas aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (ECO) and an ESBL-producing Klebsiella pneumonia (KPN).
    Type: Application
    Filed: December 21, 2020
    Publication date: April 15, 2021
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20210106640
    Abstract: Disclosed is a new drug application of a Pithecellobium clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter baumannii (MDRAB), an MDR Pseudomonas aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (ECO) and an ESBL-producing Klebsiella pneumonia (KPN).
    Type: Application
    Filed: December 21, 2020
    Publication date: April 15, 2021
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20190048361
    Abstract: The disclosure relates to an expression method of a Haemocoagulase Acutus (Halase) recombinant protein. The method includes the following steps: (1) optimizing a halase gene; (2) performing Polymerase Chain Reaction (PCR) amplification on an optimized halase gene; (3) constructing an Agkis-pMCX expression vector, transforming plasmids to competent cells of an escherichia coli for amplification, screening in an Amp-resistant manner for positive cloning, sequencing and extracting recombinant plasmids with correct sequencing; (4) transfecting recombinant plasmids to CHO cells; and (5) expressing the recombinant protein and identifying. According to the expression method, a recombinant halase is expressed first using the CHO cells cultured in a serum-free suspension manner; and by utilizing a bioengineering means, the actual production problems of insufficient raw material sources and unstable quality of a snake venom product are solved successfully.
    Type: Application
    Filed: October 30, 2018
    Publication date: February 14, 2019
    Inventors: Qin Deng, Xiao Shen, Weiwei Su, Zhong Wu, Wei Peng, Yonggang Wang
  • Patent number: 10065901
    Abstract: The present invention discloses a method for preparing optically active carbonyl compound, comprising the following steps: under the catalysis of chiral amine salt and transition metal catalysts, with hydrogen and catalytic amount of dihydropyridine compound as hydrogen source, use ?, ?-unsaturated aldehydes or ?, ?-unsaturated troponoid compounds to conduct asymmetric catalytic reaction to obtain the optically active carbonyl compound. This method comes in moderate reaction condition, simple operation, and catalytic amount of dihydropyridine compounds usage, the target product is easy to be separated and purified from the reaction system, and the metal catalyst can be recycled, it is economical.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: September 4, 2018
    Assignees: ZHEJIANG NHU COMPANY LTD., SHANDONG NHU PHARMACEUTICAL CO., LTD., ZHEJIANG UNIVERSITY
    Inventors: Yougui Zhou, Ming Yu, Jintao Yuan, Lei Zhao, Xiandong Zhu, Guangxiong Yu, Weiwei Su, Weikang Shao, Xingxing Shi, Yin Zhang, Ming Feng, Zhirong Chen, Haoran Li, Yuhong Zhang
  • Publication number: 20180200319
    Abstract: Disclosed is a new drug application of a Pithecellobium Clypearia Benth Extract (EA), and particularly is a method of the EA used for treating multiple diseases caused by drug resistant bacteria infection. Related drug resistant bacteria include a Multi-Drug Resistant (MDR) Acinetobacter Baumannii (MDRAB), an MDR Pseudomonas Aeruginosa (MDRPA), an Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia Coli (ECO) and an ESBL-producing Klebsiella Pneumonia (KPN).
    Type: Application
    Filed: March 14, 2018
    Publication date: July 19, 2018
    Inventors: Weiwei Su, Chong Liu, Qian Zhou, Peibo Li, Wei Peng, Yonggang Wang
  • Publication number: 20180105477
    Abstract: The present invention discloses a method for preparing optically active carbonyl compound, comprising the following steps: under the catalysis of chiral amine salt and transition metal catalysts, with hydrogen and catalytic amount of dihydropyridine compound as hydrogen source, use ?, ?-unsaturated aldehydes or ?, ?-unsaturated troponoid compounds to conduct asymmetric catalytic reaction to obtain the optically active carbonyl compound. This method comes in moderate reaction condition, simple operation, and catalytic amount of dihydropyridine compounds usage, the target product is easy to be separated and purified from the reaction system, and the metal catalyst can be recycled, it is economical.
    Type: Application
    Filed: November 29, 2016
    Publication date: April 19, 2018
    Inventors: YOUGUI ZHOU, MING YU, JINTAO YUAN, LEI ZHAO, XIANDONG ZHU, GUANGXIONG YU, WEIWEI SU, WEIKANG SHAO, XINGXING SHI, YIN ZHANG, MING FENG, ZHIRONG CHEN, HAORAN LI, YUHONG ZHANG