Patents by Inventor Weixue HUANG

Weixue HUANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIDOPYRIMIDINE-BASED COMPOUND AND APPLICATION THEREOF
    Publication number: 20240132492
    Abstract: The present disclosure provides a class of Pyridopyrimidine compounds having a structure shown in Formula (I) or their pharmaceutically acceptable salts, or stereoisomers or prodrug molecules and applications thereof. The compounds in the present disclosure can efficiently and selectively degrade AKT3 protein in cells without affecting AKT1/2, thereby significantly inhibiting tumor cell proliferation mediated by high expression of AKT3 protein. It can be used to prepare therapeutic drugs for cancer and other diseases related to abnormal expression of AKT3 protein.
    Type: Application
    Filed: September 6, 2023
    Publication date: April 25, 2024
    Applicants: JINAN UNIVERSITY, SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
    Inventors: Ke DING, Xin ZHANG, Fang XU, Xiaomei REN, Xiaoyun LU, Dawei MA, Weixue HUANG