Patents by Inventor Weixue Tian
Weixue Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11608334Abstract: The present invention relates to pyrrolo-aromatic heterocyclic compounds, a preparation method therefor and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a BTK kinase inhibitor. The compound and the pharmaceutical composition comprising same can be used for the treating diseases associated with BTK kinase activity, such as inflammations, autoimmune disorders, and cancers. The definition of each substituent in formula I is the same as that in the description.Type: GrantFiled: December 26, 2017Date of Patent: March 21, 2023Assignee: THE NATIONAL INSTITUTES OF PHARMACEUTICAL R&D CO., LTD.Inventors: Huijun Yin, Xu Yan, Libin Zong, Weixue Tian, Li Zheng, Haoshuai Dou, Yan Yang
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Publication number: 20220041616Abstract: The present invention relates to a spiro compound and medical uses thereof. Specifically, the present invention relates to a spiro compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the same, and is used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor and is used for treating diseases associated with ACC activity. Each substituent in the general formula (I) is as defined in description.Type: ApplicationFiled: November 20, 2019Publication date: February 10, 2022Inventors: Huijun YIN, Xu YAN, Junge WEN, Weixue TIAN, Qiyong MOU, Ning FU, Jingqian JIANG, Yao WU, Guosheng WU, Xueying FENG, Su QIAN
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Publication number: 20200062749Abstract: The present invention relates to pyrrolo-aromatic heterocyclic compounds, a preparation method therefor and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a BTK kinase inhibitor. The compound and the pharmaceutical composition comprising same can be used for the treating diseases associated with BTK kinase activity, such as inflammations, autoimmune disorders, and cancers. The definition of each substituent in formula I is the same as that in the description.Type: ApplicationFiled: December 26, 2017Publication date: February 27, 2020Applicant: The National Institutes of Pharmaceutical Research and Development (NIP)Inventors: Huijun YIN, Xu YAN, Libin ZONG, Weixue TIAN, Li ZHENG, Haoshuai DOU, Yan YANG
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Patent number: 10518829Abstract: A track pin may comprise a body that includes a generally cylindrical configuration defining an axis of rotation, a circumferential direction and a radial direction, the body defining a first end, a second end and a peripheral surface extending from the first end to the second end. The peripheral surface may include a first lobed portion spaced axially away from the first end and the second end and including a series of convex arcuate segments and concave arcuate segments joined to each other tangentially, forming an undulating surface.Type: GrantFiled: June 26, 2017Date of Patent: December 31, 2019Assignee: Caterpillar Inc.Inventors: Timothy Allen McKinley, Zhiyong Hu, Weixue Tian, William Henry Baar, III
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Publication number: 20180370583Abstract: A track pin may comprise a body that includes a generally cylindrical configuration defining an axis of rotation, a circumferential direction and a radial direction, the body defining a first end, a second end and a peripheral surface extending from the first end to the second end. The peripheral surface may include a first lobed portion spaced axially away from the first end and the second end and including a series of convex arcuate segments and concave arcuate segments joined to each other tangentially, forming an undulating surface.Type: ApplicationFiled: June 26, 2017Publication date: December 27, 2018Applicant: Caterpillar Inc.Inventors: Timothy Allen McKinley, Zhiyong Hu, Weixue Tian, William Henry Baar, III
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Patent number: 9970523Abstract: A torque converter includes a housing, and an impeller shell disposed within the housing. The impeller shell has a back wall, and a plurality of fins radially arranged and extending outwardly from the back wall. The torque converter further includes a backing hub rigidly coupled to the back wall of the impeller shell. The backing hub has a barrier element extending therefrom. A free end of the barrier element is disposed proximal to the housing to restrict a flow of fluid therebetween.Type: GrantFiled: August 28, 2015Date of Patent: May 15, 2018Assignee: Caterpillar Inc.Inventors: Valerie Annette Ross, Xuekui Lan, Jim Wu, Qinyang Rao, Timothy M. Waters, Weixue Tian
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Publication number: 20170059022Abstract: A torque converter includes a housing, and an impeller shell disposed within the housing. The impeller shell has a back wall, and a plurality of fins radially arranged and extending outwardly from the back wall. The torque converter further includes a backing hub rigidly coupled to the back wall of the impeller shell. The backing hub has a barrier element extending therefrom. A free end of the barrier element is disposed proximal to the housing to restrict a flow of fluid therebetween.Type: ApplicationFiled: August 28, 2015Publication date: March 2, 2017Applicant: Caterpillar Inc.Inventors: Valerie Annette Ross, Xuekui Lan, Jim Wu, Qinyang Rao, Timothy M. Waters, Weixue Tian
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Patent number: 8960227Abstract: A tank for a hydraulic fluid has a housing with opposed end walls and side walls defining an interior chamber. A primary baffle is disposed inside the housing and divides the interior chamber into an inlet chamber and an outlet chamber, with a primary gap between the primary baffle and the housing fluidly communicating between the inlet chamber and the outlet chamber. The primary baffle further defines a contact surface facing the inlet chamber and has first and second weirs which extend into the inlet chamber. A first fluid inlet fluidly communicates with the inlet chamber and is oriented along a first inlet axis that intersects the contact surface, while a fluid outlet communicates with the outlet chamber. The tank produces an interior flow that mixes and deaerates the fluid as it travels from the first fluid inlet to the fluid outlet.Type: GrantFiled: March 16, 2012Date of Patent: February 24, 2015Assignee: Caterpillar SARLInventors: Sage Frederick Smith, Brian Franklin Taggart, Xuekui Lan, Weixue Tian
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Publication number: 20130240069Abstract: A tank for a hydraulic fluid has a housing with opposed end walls and side walls defining an interior chamber. A primary baffle is disposed inside the housing and divides the interior chamber into an inlet chamber and an outlet chamber, with a primary gap between the primary baffle and the housing fluidly communicating between the inlet chamber and the outlet chamber. The primary baffle further defines a contact surface facing the inlet chamber and has first and second weirs which extend into the inlet chamber. A first fluid inlet fluidly communicates with the inlet chamber and is oriented along a first inlet axis that intersects the contact surface, while a fluid outlet communicates with the outlet chamber. The tank produces an interior flow that mixes and deaerates the fluid as it travels from the first fluid inlet to the fluid outlet.Type: ApplicationFiled: March 16, 2012Publication date: September 19, 2013Applicant: CATERPILLAR, INC.Inventors: Sage Frederick Smith, Brian Franklin Taggart, Xuekui Lan, Weixue Tian