Patents by Inventor Wen-fu Lai

Wen-fu Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240157217
    Abstract: A golf teaching method and a golf teaching system are provided. The golf teaching method includes: configuring image capturing devices and golf simulator to capture swing images and corresponding simulator data records, when a user performs a golf swing; configuring an expert model that includes expert motion information and corresponding correction suggestion information; configuring a computing device to perform an analysis process on the swing images and the simulator data records to divide the golf swing into user motions according to stages and obtaining records of user motion information corresponding to the plurality of stages, and to compare the user motion information with the corresponding expert motion information in each stage through the expert model, and to provide the corresponding correction suggestion information according to a comparison result; and configuring a user interface to provide the correction suggestion information.
    Type: Application
    Filed: April 20, 2023
    Publication date: May 16, 2024
    Inventors: CHENG-HUNG TSAI, CHIA-YU JIH, CHIH-CHUNG CHIEN, LI-LIN LU, SHAO-JUN TAN, WEN-FU LAI
  • Publication number: 20230201417
    Abstract: A pharmaceutical composition for eardrum repair includes: collagen present in an amount of 8 wt % to 12 wt %; a forming agent present in an amount of 19 wt % to 22 wt %; and rest of a solvent, wherein the forming agent is a polymer of polyethylene oxide (PEO) and polypropylene oxide (PPO), polystyrene, polyethylene, polypropylene, polymethylmethacrylate, poly(N-isopropylacrylamide), poly[2-(dimethylamino)ethyl methacrylate] (pDMAEMA) hydroxypropylcellulose, poly(vinylcaprolactame), poly-2-isopropyl-2-oxazoline, polyvinyl methyl ether or a combination thereof.
    Type: Application
    Filed: December 27, 2021
    Publication date: June 29, 2023
    Inventors: Wen-Fu Lai, Li-Hsuan Chiu, Fu-Chen Kung
  • Publication number: 20220184235
    Abstract: A probe for monitoring new bone formation and osseointegration containing an integrin ?5?1 ligand conjugated to a near-infrared fluorescent dye in which the integrin ?5?1 ligand is a cyclic peptide lacking an RGD sequence. Also disclosed is a bone repair and osteogenesis-monitoring probe formed of a bisphosphonate conjugated to a gold nanoparticle, the probe having a size of 1 nm to 10 nm. Further disclosed are two methods for monitoring bone formation, each of which is carried out by administering the above probes and obtaining a near-infrared fluorescence image.
    Type: Application
    Filed: December 10, 2021
    Publication date: June 16, 2022
    Inventors: Wen-Fu Lai, Yun-Ming Wang, Cheng-An Lin, Li-Hsuan Chiu, Hong-Shong Chang
  • Publication number: 20150147720
    Abstract: The present invention relates to a tooth-replacement implant, comprising: a main body portion and a root cervical portion, wherein the root body portion has a plurality of lateral pores and a hollow thorough hole at the bottom. Further, a collagen coating layer and an anti-bacterial coating layer are formed on the surface of the body portion root. Therefore, the present invention may increase bone contact area and enhance stability, and thereby avoiding compressing nerve to cause paralysis of perception through the implant and avoiding the sinus perforation.
    Type: Application
    Filed: June 30, 2014
    Publication date: May 28, 2015
    Inventors: Wen-Fu LAI, Chien-Chou LIN, Mao-Suan HUANG, Wu-Hsiung LIN
  • Patent number: 8431399
    Abstract: The present invention provides a method for restoring native chondrocyte phenotype and functions of, and/or increasing type II collagen as well as aggrecan mRNA expression levels and GAG accumulation level in dedifferentiated chondrocytes which have been subcultured and expanded in vitro, which comprising culturing the said dedifferentiated chondrocytes in vitro with a medium comprising type II collagen, or its biologically active peptide fragment(s) or analogs with or without growth factor(s), wherein the type II collagen or its biologically active peptide fragment(s) or analogs are effective to restore chondrocyte phenotype and functions of, and/or to increase type II collagen and aggrecan expression levels and GAG accumulation level in the said dedifferentiated chondrocytes.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: April 30, 2013
    Assignee: Taipei Medical University
    Inventors: Yu-Hui Tsai, Li-Hsuan Chiu, Chin-Chean Wong, Wen-Fu Lai, Shih-Ching Chen
  • Publication number: 20130030045
    Abstract: The invention discloses a method of preventing and treating osteoporosis. The method comprises a step of enhancing osteoblast differentiation and inhibiting osteoclast differentiation by administering a pharmaceutically effective amount of a composition comprising 6-hydroxy flavone compound or 7-methoxy flavone compound, or at least one pharmaceutically acceptable salt thereof to a subject.
    Type: Application
    Filed: August 6, 2012
    Publication date: January 31, 2013
    Inventors: Yu-Hui TSAI, Yu-Wei Wu, Yu-Hsiang Lin, Wen-Fu Lai, Shih-Ching Chen
  • Publication number: 20110262486
    Abstract: The invention discloses a bone implant and a manufacturing method thereof. The manufacturing method of the bone implant comprises a step of coating or mixing type II collagen with at least one porous bone material comprising metals, bio-ceramics, natural biopolymers and synthetic polymers. Another manufacturing method of the bone implant comprises the steps of loading type II collagen with or without at least one porous bone material in a container, and lyophilizing the type II collagen to generate a type II collagen sponge construct with or without the porous bone material as the bone material. The manufactured bone implants are effective, with or without loading cells having differentiation tendency towards osteogenesis, to facilitate bone repair upon introduction of the bone implant into various osseous defects.
    Type: Application
    Filed: April 22, 2010
    Publication date: October 27, 2011
    Applicant: TAIPEI MEDICAL UNIVERSITY
    Inventors: Yu-Hui Tsai, Li-Hsuan Chiu, Wen-Fu Lai, Shih-Ching Chen
  • Publication number: 20110217773
    Abstract: The present invention provides a method for restoring native chondrocyte phenotype and functions of, and/or increasing type II collagen as well as aggrecan mRNA expression levels and GAG accumulation level in dedifferentiated chondrocytes which have been subcultured and expanded in vitro, which comprising culturing the said dedifferentiated chondrocytes in vitro with a medium comprising type II collagen, or its biologically active peptide fragment(s) or analogs with or without growth factor(s), wherein the type II collagen or its biologically active peptide fragment(s) or analogs are effective to restore chondrocyte phenotype and functions of, and/or to increase type II collagen and aggrecan expression levels and GAG accumulation level in the said dedifferentiated chondrocytes.
    Type: Application
    Filed: March 2, 2010
    Publication date: September 8, 2011
    Applicant: TAIPEI MEDICAL UNIVERSITY
    Inventors: Yu-Hui Tsai, Li-Hsuan Chiu, Chin-Chean Wong, Wen-Fu Lai, Shih-Ching Chen
  • Publication number: 20060190091
    Abstract: This invention relates to a bone implant that includes a bioinert substrate covered with a ceramic layer containing a plurality of indentations. The total surface area of the indentations is 30-70% of the total surface area of the ceramic layer. This invention also relates to a method of preparing such a bone implant. The method includes: (1) affixing a ceramic layer on the surface of a bioinert substrate; (2) forming a plurality of indentations in the ceramic layer, wherein the total surface area of the indentations is 30-70% of the total surface area of the ceramic layer; and (3) immobilizing a biopolymer onto the ceramic layer via covalent bonding.
    Type: Application
    Filed: February 22, 2005
    Publication date: August 24, 2006
    Inventors: Wen-Fu Lai, Li-Chern Pan, Pau-Yee Lim, Jung-Chou Oung, Chun-Wei Chen
  • Patent number: 5876444
    Abstract: The present invention relates to a process of preparation of a new reconstituted collagen template and further to the reconstituted collagen template being able to cure articular destruction in a mammal.
    Type: Grant
    Filed: April 1, 1996
    Date of Patent: March 2, 1999
    Inventor: Wen-fu Lai