Abstract: A camera optical lens is provided. The camera optical lens includes, from an object side to an image side, a first lens, a second lens having a positive refractive power, a third lens, a fourth lens, a fifth lens, a sixth lens, a seventh lens, an eighth lens, and a ninth lens. The camera optical lens satisfies following conditions: 1.80?f1/f?3.20; and 1.50?d11/d12?8.00, where f1 denotes a focal length of the first lens, d11 denotes an on-axis thickness of the sixth lens, and d12 denotes an on-axis distance from an image side surface of the sixth lens to an object side surface of the seventh lens. The camera optical lens according to the present disclosure meets design requirements for large aperture, wide angle and ultra-thinness while achieving good optical performance.

Abstract: A photosensitizer molecule increases the retention time thereof in a tumor and the enhancement of the therapy for large-volume tumors. AN-BDP is synthesized by means of introducing anthracene into BODIPY-meso, and due to the strong intermolecular ?-? interaction of anthracene, AN-BDP and an amphiphilic block copolymer DSPE-PEG2000 are self-assembled into stable nanoparticles AN-BDP NPs. By means of anthracene, AN-BDP can be excited to a triplet excited state under light irradiation and acts with O2 to generate 1O2. AN-BDP NPs are enriched at the tumor site and retained for about 10 days after tail vein injection. In a mouse tumor model having a conventional volume tumor, AN-BDP NPs can completely inhibit the growth of the tumor by means of one-time tail vein injection and one-time photoirradiation therapy.

Abstract: An array substrate is provided. The array substrate includes an anode layer including a plurality of anodes on the base substrate, a respective anode being at least partially in a respective subpixel region; a carrier transport blocking layer on a side of the anode layer away from the base substrate, the carrier transport blocking layer at least partially blocking carrier transport; a pixel definition layer on a side of the carrier transport blocking layer away from the base substrate, the pixel definition layer defining subpixel apertures, a respective subpixel aperture exposing at least a portion of the respective anode; and an organic layer including at least a first portion in the respective subpixel region and on a side of the anode layer away from the base substrate.

Abstract: The present disclosure relates to the field of optical lenses, and discloses a camera optical lens. The camera optical lens includes eight lenses, and the eight lenses includes successively from an object side to an image side: a first lens having negative refractive power, a second lens having positive refractive power, a third lens, a fourth lens, a fifth lens, a sixth lens, a seventh lens, and an eighth lens. An object side surface of the eighth lens is a convex surface at a paraxial position, an image side surface thereof is a concave surface at a paraxial position, and at least one of the first lens to the eighth lens includes a free-form surface. The camera optical lens of the present disclosure has good optical performance while meeting design requirements of a large aperture, ultra-thinness, and a wide angle while.

Abstract: The present disclosure provides a camera optical lens including eight lenses which are, from an object side to an image side in sequence: a first lens having a positive refractive power, a second lens having a positive refractive power, a third lens having a positive refractive power, a fourth lens having a negative refractive power, a fifth lens having a negative refractive power, a sixth lens having a positive refractive power, a seventh lens having a negative refractive power, and an eighth lens having a negative refractive power; the camera optical lens satisfies conditions of: 0.95?f/TTL; 3.00?f2/f?5.00; and 3.50?(R9+R10)/(R9?R10)?30.00. The camera optical lens can achieve good optical performance while meeting the design requirements for large aperture, long focal length and ultra-thinness.

Abstract: A camera optical lens is provided, including from an object side to an image side: a first lens having negative refractive power; a second lens having positive refractive power; a third lens having negative refractive power; a fourth lens having positive refractive power; and a fifth lens having negative refractive power. The camera optical lens satisfies following conditions: ?6.00?f3/f??3.70; ?3.00?R2/R1??0.80; 2.10?d6/d8?6.00; and 3.00?d3/d4?12.00. The above camera optical lens may meet design requirements on large aperture, wide angle and ultra-thinness, while maintaining a high imaging quality.

Abstract: This present invention relates to methods for improved assays to quantify the level of chromatin targets from biological samples. These assays can be used for the detection of global levels of epigenetic modifications (e.g., histone and DNA modifications), chromatin associated proteins, or chromatin associated ribonucleic acids (RNA). The invention further relates to assay kits that include the reagents needed to prepare biological samples and perform said improved chromatin assays.

Abstract: The present invention provides a camera optical lens, including, from an object side to an image side, a first lens having a positive refractive power, a second lens having a negative refractive power, a third lens having a positive refractive power, a fourth lens having a positive refractive power, and a fifth lens having a negative refractive power. At least one of the first to fifth lenses has a free-form surface, and the camera optical lens satisfies: 2.00?f3/f?5.50; 2.00?R4/R3?23.00, where f is a focal length of the camera optical lens, f3 is a focal length of the third lens, R3 is a central curvature radius of an object side surface of the second lens, and R4 is a central curvature radius of an image side surface of the second lens. The camera optical lens satisfies requirements of a large aperture, a wide angle and ultra-thinness, and has excellent optical performance.

Abstract: Provided is a camera optical lens including, sequentially from an object side to an image side: a first lens having a negative refractive power; a second lens; a third lens having a positive refractive power; a fourth lens having a negative refractive power; a fifth lens; a sixth lens having a positive refractive power; and a seventh lens having a negative refractive power. At least one of the first to seventh lenses comprises a free-form surface. The camera optical lens can achieve high optical performance while satisfying design requirements for ultra-thin, wide-angle lenses.

Abstract: The present invention relates to the field of optical lenses, and provides a camera optical lens, including, from an object side to an image side, a first lens having a positive refractive power, a second lens a negative refractive power, a third lens having a positive refractive power, a fourth lens having a negative refractive power, and a fifth lens. At least one of the first lens to the fifth lens has a free-form surface, and the camera optical lens satisfies: 0?R7; and R10?0, where R7 denotes a central curvature radius of an object side surface of the fourth lens, and R10 denotes a central curvature radius of an image side surface of the fifth lens. The camera optical lens provided by the present invention satisfies design requirements of a long focal length and ultra-thinness while having excellent optical performance.

Abstract: Disclosed is a camera optical lens, comprising, from an object side to an image side in sequence: a first lens having a negative refractive power; a second lens having a positive refractive power; a third lens having a negative refractive power; a fourth lens having a positive refractive power; and a fifth lens having a negative refractive power; the camera optical lens satisfies: ?5.00?f1/f??3.00; ?1.50?f5/f??1.00; 1.20?(R7+R8)/(R7?R8)?3.00; and 8.00?d7/d8?14.00; where, f denotes a focus length of the camera optical lens; f1 and f5 denotes focus length of the first and fifth lens respectively; R7 and R 8 denote central curvature radii of an object side surface and an image side surface of the fourth lens respectively; d7 denotes an on-axis thickness of the fourth lens; and d8 denotes an on-axis distance from the image side surface of the fourth lens to an object side surface of the fifth lens.

Abstract: A camera optical lens includes, from an object side to an image side: a first lens having a negative refractive power; a second lens having a positive refractive power; a third lens having a positive refractive power; a fourth lens having a positive refractive power; and a fifth lens having a negative refractive power. 2.50?f3/f?6.00, ?2.00?R4/R3??1.00, and 1.00?d1/d2?1.80. f denotes a focal length of the camera optical lens; f3 denotes a focal length of the third lens; R3 denotes a curvature radius of an object-side surface of the second lens; R4 denotes a curvature radius of an image-side surface of the second lens; d1 denotes an on-axis thickness of the first lens; d2 denotes an on-axis distance from an image-side surface of the first lens to an object-side surface of the second lens. The camera optical lens can achieve good optical performance while achieving ultra-thin, wide-angle lenses having large apertures.

Abstract: The invention provides a nutritional value prediction system. A nutritional value of processed food is predicted based on an identity of food to be processed and processing characteristics of a kitchen appliance used to process the food to be processed. Processing characteristics of the kitchen appliance are determined based on a sensed parameter of a power supply of the kitchen appliance.

Abstract: A camera optical lens includes, from an object side to an image side, a first lens having a positive refractive power, a second lens having a negative refractive power, a third lens having a positive refractive power, a fourth lens having a negative refractive power, and a fifth lens, with at least one of the first to fifth lenses having a free-form surface, and satisfies: ?3.50?f4/f??0.35; ?8.00?R10/f??1.00; and 2.00?d8/d7?8.00, where f and f4 respectively denote focal lengths of the camera optical lens and the fourth lens; R10 denotes a central curvature radius of an image side surface of the fifth lens; d7 denotes an on-axis thickness of the fourth lens; and d8 denotes an on-axis distance from an image side surface of the fourth lens to an object side surface of the fifth lens, thereby having good optical performance while satisfying design requirements of a long focal length and ultra-thinness.

Abstract: The present invention relates to the field of optical lenses, and provides a camera optical lens, including, from an object side to an image side, a first lens, a second lens, a third lens, a fourth lens, and a fifth lens. At least one of the first lens to the fifth lens has a free-form surface, and the camera optical lens satisfies: ?3.50?f2/f??1.50; ?2.00?(R5+R6)/(R5?R6)?0.20; and 1.00?f4/f?5.50, where f denotes a focal length of the camera optical lens, f2 denotes a focal length of the second lens, f4 denotes a focal length of the fourth lens, R5 denotes a central curvature radius of an object side surface of the third lens, and R6 denotes a central curvature radius of an image side surface of the third lens. The camera optical lens according to the present invention has a large aperture, a wide angle and ultra-thinness, as well as excellent optical performance.

Abstract: The invention relates generally to methods for preparing recombinant nucleosomes. In particular, the invention relates to methods for ligating a histone peptide onto a fully assembled recombinant nucleosome. The invention further relates to modified core histone proteins, histone peptides to be ligated to the modified core histone proteins, and fully assembled recombinant nucleosomes and libraries of recombinant nucleosomes prepared by the methods of the invention.