Abstract: The invention discloses the medicinal use of kaurene compound in the prevention and treatment of sepsis, systemic inflammatory response syndrome (SIRS) and multiple organ failure caused by sepsis, including acute pulmonary failure, acute heart failure and renal failure.

Abstract: Methods of analyzing cells, including interactions among different populations of cells. Methods include cell-containing liquid droplets with oligonucleotide-containing liquid droplets, hybridizing oligonucleotides to target nucleic acids from cells, extending the hybridized oligonucleotides on the target nucleic acids into cell identifier sequences on the target nucleic acids, and thereby identifying the type of cells initially present. The methods can be implemented in a high-throughput manner in a microfluidic system.

Abstract: The present disclosure relates to an organic electroluminescence display panel, a fabricating method thereof, and a corresponding display device. The organic electroluminescence display panel includes: a base substrate including a display area; a gate driving circuit and a plurality of pixel driving circuits located in the display area; and a plurality of top emission type of light-emitting units located in the display area. An orthographic projection of the gate driving circuit on the base substrate at least partially overlaps with an orthographic projection of the plurality of top emission type of light-emitting units on the base substrate.

Abstract: The present invention relates to a novel crystalline form of (R)-terbutaline hydrochloride salt, its process and its therapeutically uses.

Abstract: In some examples, the disclosure relates to a medical device such as an implantable medical lead. The medical lead may include: a lead body including an electrically conductive lead wire; an electrical contact on a proximal portion of the lead body, the electrical contact including a contact substrate; and an electrode on a distal portion of the lead body, the electrode including an electrode substrate, wherein the electrode substrate is electrically coupled to the contact substrate via the electrically conductive lead wire, wherein the lead wire is formed of a composition comprising titanium or titanium alloys, wherein the electrode substrate is formed of a first beta-titanium alloy, and wherein the contact substrate is formed of a second beta-titanium alloy.

Abstract: A method is provided and includes several operations: arranging multiple channels extending in a first direction; arranging, in accordance with multiple weights of multiple macros, a first portion of the macro closer to a centroid of a core region of an integrated circuit than a second portion of the macros; and arranging the macros on opposite sides of the channels. The macros have multiple pins coupled to the channels interposed between the macros.

Abstract: A method is provided and includes several operations: forming a first group of macros in a first region, wherein the first group of macros are aligned with a first boundary of a channel that is coupled thereto through pins of the first group of macros; forming a second group of macros in the first region to align with a second boundary of the channel that is coupled thereto through pins of the second group of macros, wherein the first and second groups of macros are coupled to a first register; and forming a third group of macros in a second region different from the first region. A first macro and a second macro that are in the third group of macros are aligned with the first and second boundaries respectively. The third group of macros are coupled to a second register different from the first register.

Abstract: This invention disclosed new use of R-terbutaline and other R-enantiomer ?2-agonists as immune-modulators for treatment of bronchia-lung inflammatory symptoms or inflammatory fibrosis remolding. This invention also disclosed new use of R-terbutaline and R-?2-agonists for reduced adverse effects related to racemic or S-enantiomer ?2-agonists including airway hyper responsiveness and airway fibrosis.

Abstract: A display substrate of the present disclosure includes a display region including sub-pixels, data lines, and gate lines; and a circuit region including a first sub-region and a second sub-region opposite to each other at two sides of the display region along a first direction. The first sub-region is provided with a plurality of multiplexing unit groups, each of which includes at least one multiplexing unit. The second sub-region is provided with a plurality of testing unit groups, each of which includes at least one testing unit. The circuit region is further provided with a plurality of driving unit groups, each of which includes at least one driving unit. The driving unit groups and the multiplexing unit groups are alternately arranged along an extending direction of the first sub-region in the first sub-region.

Abstract: A method is provided in the present disclosure. The method includes several operations: generating a floor plan having multiple macros for an integrated circuit; adjusting the macros according to a channel area interposed between the pins; separating the macros by a channel width of the channel area; and adjusting, in accordance with correlations between the macros and multiple registers, the macros in the floor plan.

Abstract: The present disclosure relates to an organic light-emitting backplane and manufacturing method thereof, a touch display screen and a touch display device. The organic light-emitting backplane comprises a display region and a non-display region located around the display region, the organic light-emitting backplane in the non-display region comprising: a first substrate; a padding layer located on a side of the first substrate, the padding layer comprising a body portion and a convex pattern portion located on a side of the body portion away from the first substrate; and a first wiring layer located on a side of the padding layer away from the first substrate, at least apart of the first wiring layer being formed on a surface of the convex pattern portion.

Abstract: The present disclosure provides an array substrate and a display device. The array substrate includes a display region and a non-display region located at a periphery of the display region. The display region includes a plurality of pixel structures, and an outgoing line of each of the pixel structures is overlapped with and connected to a connection line. The connection line receives a signal provided by a signal supply circuit. An area of a contact interface between at least part of the connection line and the outgoing line is larger than an area of an orthographic projection of the contact interface on a plane where the array substrate is located.

Abstract: Synthesis of novel kaurane analogues , their preparation, and their uses in cardiac protection against ischemia, hypertrophy and chemotherapy induced cardiomyopathy as well as cerebral ischemia.

Abstract: The object of the present invention is to provide an easy and quick detection method for detecting an oxLDL/?2GPI complex in biological samples, and a detection kit therefor. The present invention attains this object by providing a detection method for detecting an oxLDL/?2GPI complex, which uses a test strip for lateral flow assay, comprising a step of capturing the oxLDL/?2GPI complex in the test sample in a predetermined position on the test strip by a first binding component that binds to the oxLDL/?2GPI complex; and a step of labeling the oxLDL/?2GPI complex captured in the predetermined position on the test strip by making a second binding component comprising a labeling agent be bound to the captured oxLDL/?2GPI complex, and a detection kit therefor.

Abstract: A display panel and a display device are provided. The display panel includes: a plurality of first pixel units, a plurality of second pixel units, a plurality of third pixel units and a plurality of first data lines. An effective light-emitting area of the first pixel unit is larger than an effective light-emitting area of the second pixel unit, and larger than an effective light-emitting area of the third pixel unit orthographic projection of the first data line on the base substrate is not overlapped with an orthographic projection of any one of the first electrode of the first pixel unit, the first electrode of the second pixel unit, and the first electrode of the third pixel unit on the base substrate.

Abstract: A gas leak detector cartridge includes a cartridge housing that is removably installed in a handheld device. The cartridge housing includes a sensor that detects a presence of a contaminant in a sample gas and is connected to a printed circuit board. The cartridge housing also includes a pump positioned in a manifold and introduces a sample gas to the sensor. The sensor is at least partially inserted into the manifold that includes the pump.

Abstract: A method is provided in the present disclosure. The method includes several operations: generating a floor plan having multiple macros for an integrated circuit; adjusting the macros according to a channel area interposed between the pins; separating the macros by a channel width of the channel area; and adjusting, in accordance with correlations between the macros and multiple registers, the macros in the floor plan.

Abstract: A method for non-destructive detection of egg freshness based on centroid measurement. A real-time distance between the centroid position of an egg and the top of a small end of the egg is measured, the ratio of the distance to the length of the egg is defined as a centroid ratio, models are respectively established regarding a centroid ratio change and the number of days the egg has been stored, and regarding the centroid ratio change and the egg freshness, and the number of the days the egg has been stored and the egg freshness are predicted by means of the established models.

Abstract: A method, for determining constraints related to a target circuit, includes following operations. First circuit speed results of the target circuit under different candidate constraint configurations are accumulated. Breakthrough probability distributions relative to each of the candidate constraint configurations are determined according to the first circuit speed results. First selected constraint configurations are determined from the candidate constraint configurations by sampling the breakthrough probability distributions. A first budget distribution is determined among the first selected constraint configurations. In response to that the first budget distribution is converged, the first selected constraint configurations in the first budget distribution is utilized for implementing the target circuit and generating an updated circuit speed result of the target circuit.

Abstract: Provided are a touch display panel and a method for preparing the touch display panel. The touch display panel includes a base substrate, a display substrate disposed on the base substrate, and a touch substrate disposed on the display substrate, wherein the display substrate comprises a plurality of pixel units arranged in a matrix, the pixel units each comprise a plurality of sub-pixels, the touch substrate comprises a touch electrode layer, the touch electrode layer comprises a plurality of hollow regions, and an orthographic projection of a hollow region on the base substrate contains an orthographic projection of at least one sub-pixel or at least one pixel unit on the base substrate.