Abstract: The present invention relates to compounds of Formula (XI): wherein R1a, R2a, R3a, R4a, R5a, R6a, and Aa are as defined herein, and pharmaceutically acceptable salts thereof. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) inhibitors and can be useful in the treatment of Duchenne Muscular Dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

Abstract: A calf protector for rowers, comprising a single strip of neoprene (or a similar synthetic or natural rubber) covered by nylon (or other fabric having loops) with a strip of hook fasteners (as in VELCRO®) on one end. The neoprene strip is wider in the main middle part, and narrower at the ends. Hook fasteners on the inside surface at one end of the strip can engage loops in the fabric on the outside surface at the opposite end of the strip (or visa versa) so that it forms a loop around the rower's leg, to protect the back of the leg from friction against the front ends of rails on which the seats in a boat move when rowing. The invention may also be used by other persons to protect their legs and/or arms. The invention encompasses both an apparatus and a method for protecting limbs using the apparatus.

Abstract: The present invention provides 2-pyrimidinyl pyrazolopyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.

Abstract: A calf protector for rowers, comprising a single strip of neoprene (or a similar synthetic or natural rubber) with strips of hook and loop fasteners (commonly known as “VELCRO®”) on its ends. The neoprene strip is wider in the main middle part, and narrower at the ends with the strips of hook and loop fasteners. Hook fasteners on the inside surface at one end of the strip can engage loop fasteners on the outside surface at the opposite end of the strip (or visa versa) so that it forms a loop around the rower's leg, to protect the back of the leg from friction against the front ends of rails on which the seats in a boat move when rowing. The invention may also be used by other persons to protect their legs and/or arms. The invention encompasses both an apparatus and a method for protecting limbs using the apparatus.

Abstract: The invention consists of a system of integrated components comprised of at least one portable data storage device, a secure server based system to warehouse data within a database and an image of the computer readable media on the portable data storage device, and a user interface to the secure server. It is contemplated that access to the secure server can be accomplished through a browser via the internet, an intranet, or an extranet. It is further contemplated that a secure client/server arrangement could permit direct access to the database. A client/server arrangement could be of a thin-client or fat-client type architecture. Users would require only a minimal amount of interaction with the system for the purpose of editing information and uploading files, while health care providers would require greater access and reporting for the purpose of facilitating the delivery of appropriate care.

Abstract: The present invention provides 2-pyrimidinyl pyrazolopyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.

Abstract: A support and transport system for a patient care apparatus comprised of a first arm assembly connected to a stationary support and a second arm assembly connected to a patient transfer vehicle. An end cap for supporting a patient care apparatus is selectively attachable to the first arm assembly and to the second arm assembly. Locking means are provided on the end cap for locking the end cap onto one of the first and second arm assemblies. The other of the first and second arm assemblies is detachable from the end cap only when the end cap is locked onto the one of the first and second arm assemblies.

Abstract: The present invention is an accumulated light meter that generates data concerning the quantity of photosynthetically active radiation available over a measured period of time. The device can calculate a daily light integral (DLI) that corresponds to the amount of light required by certain plants in order to optimize photosynthesis. The device also possesses the ability to filter out the effect that wavelengths of unproductive light have on the calculated values since not all light is conducive to photosynthesis and different species of plants can utilize different wavelengths of light in dissimilar ways.

Abstract: A support and transport system for a patient care apparatus comprised of a first arm assembly connected to a stationary support and a second arm assembly connected to a patient transfer vehicle. An end cap for supporting a patient care apparatus is selectively attachable to the first arm assembly and to the second arm assembly. Locking means are provided on the end cap for locking the end cap onto one of the first and second arm assemblies. The other of the first and second arm assemblies is detachable from the end cap only when the end cap is locked onto the one of the first and second arm assemblies.

Abstract: A portable fish finder device with a housing that defines a wrap cavity for receiving a signal cable that communicates between a depth finder device and a transducer attached to the water craft. A skirt connected to the housing moves between a first position covering the wrap cavity and a second position uncovering the cavity for winding or unwinding the signal cable. The depth finder device pivotally mounts to the housing to move between a storage position with a display screen received in a recess of the housing and an extended position for viewing the display. The cable winds into the wrap cavity for storage and unwinds when the housing is disposed on a portion of a water craft for use of the depth finder with the transducer communicating signals in a body of water for detecting underwater articles.

Abstract: The present invention provides novel indane-like compounds which can be useful for treating psychosis and other conditions associated with the modulation of a muscarinic receptor. The invention provides formulations and methods for using the novel compounds.