Patents by Inventor Wendy Naimark
Wendy Naimark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9248216Abstract: The present invention is generally directed to medical devices, and more specifically to medical devices that are at least partially insertable or implantable into the body of a patient. The medical devices generally comprise (a) a therapeutic agent, more typically, a high-molecular-weight therapeutic agent, and (b) at least one polymeric layer, which typically acts to control the release of the therapeutic agent from the medical device. Also disclosed herein are methods of making such medical devices.Type: GrantFiled: January 28, 2013Date of Patent: February 2, 2016Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Maria Palasis, Wendy Naimark, Robert E. Richard
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Publication number: 20150073388Abstract: The present invention provides systems and methods for the targeted delivery of a therapeutic agent using expandable devices that are temporarily or permanently placed within the body. Such therapeutic agents may be delivered as a coating on the outer surface of the expandable device. Once positioned at a desired location within the body, the device is expanded such that its drug-coated outer surface establishes direct contact with a target tissue. The expanded device remains in contact with the target tissue for a pre-determined amount of time prior to being withdrawn from the body. Delivery of the therapeutic agent using the expandable device may be followed, or preceded, by delivery of a second expandable device to the same location within the body.Type: ApplicationFiled: September 9, 2014Publication date: March 12, 2015Inventors: Maria PALASIS, Danny CONCAGH, Lee CORE, Stephanie WEBBER, Yina KUANG, Wendy NAIMARK, Raymond Knox
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Patent number: 8808364Abstract: The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.Type: GrantFiled: September 22, 2011Date of Patent: August 19, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Timothy J. Mickley, Toby Freyman, Wendy Naimark
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Publication number: 20140172074Abstract: The present invention relates generally to stents for insertion into bodily lumens that include at least one strand that forms a self-expanding tubular structure. Specifically, these strands form a plurality of intersections at which one portion of the strand is in proximity to another portion of the same or different strand. More specifically, at least some of those intersections include a plurality of reinforcement members.Type: ApplicationFiled: December 13, 2012Publication date: June 19, 2014Applicant: 480 BIOMEDICAL, INC.Inventors: Danny Concagh, Maria Palasis, Yina Kuang, Stephanie Webber, Kicherl Ho, Wendy Naimark
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Patent number: 8740844Abstract: The present invention generally relates to a medical device for delivering a therapeutic agent to an internal portion of a patient's body. The medical device includes a shaft and a self-expanding delivery member in operative communication with the shaft. The delivery member is shaped from a porous material that is capable of releasing a therapeutic agent to an internal portion of a patient's body. The medical device further includes a therapeutic agent delivery lumen in fluid communication with the delivery member to fluidly connect the delivery member with a therapeutic agent source. A retention member may also be provided to selectively collapse the delivery member.Type: GrantFiled: August 20, 2003Date of Patent: June 3, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Toby Freyman, Timothy J. Mickley, Maria J. Palasis, Wendy Naimark
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Patent number: 8739727Abstract: The medical device of the invention comprises a surface comprising at least one outermost portion and a plurality of depressions. The depressions occupy at least about 80% of the surface area of the surface. The depressions contain a coating material that preferably comprises a biologically active material and/or polymer, and the outermost portion is substantially free of any coating material. The invention is also directed to a method for manufacturing a medical device. The method comprises applying a coating material to the surface of the medical device by using at least one roller.Type: GrantFiled: October 8, 2012Date of Patent: June 3, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Michael Austin, Don Robinson, Dennis R. Boulais, Praveen Kulkarni, Toby Freyman, Samuel J. Epstein, Wendy Naimark, Marlene Schwarz
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Patent number: 8361143Abstract: The present invention is generally directed to medical devices, and more specifically to medical devices that are at least partially insertable or implantable into the body of a patient. The medical devices generally include (a) a therapeutic agent, more typically, a high-molecular-weight therapeutic agent, and (b) at least one polymeric layer, which typically acts to control the release of the therapeutic agent from the medical device. Also disclosed herein are methods of making such medical devices.Type: GrantFiled: January 7, 2009Date of Patent: January 29, 2013Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Wendy Naimark, Robert E. Richard
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Patent number: 8281737Abstract: The medical device of the invention comprises a surface comprising at least one outermost portion and a plurality of depressions. The depressions occupy at least about 80% of the surface area of the surface. The depressions contain a coating material that preferably comprises a biologically active material and/or polymer, and the outermost portion is substantially free of any coating material. The invention is also directed to a method for manufacturing a medical device. The method comprises applying a coating material to the surface of the medical device by using at least one roller.Type: GrantFiled: March 9, 2004Date of Patent: October 9, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Michael Austin, Don Robinson, Dennis R. Boulais, Praveen Kulkarni, Toby Freyman, Samuel J. Epstein, Wendy Naimark, Marlene Schwarz
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Publication number: 20120231047Abstract: Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.Type: ApplicationFiled: May 24, 2012Publication date: September 13, 2012Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Robert A. Herrmann, John J. Damarati, Sepideh Hashemi, Wendy Naimark, Barry N. Gellman, Robert Rioux, Alexandra Rousseau, Raymond Lareau
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Patent number: 8235937Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.Type: GrantFiled: February 7, 2011Date of Patent: August 7, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein
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Publication number: 20120053517Abstract: Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.Type: ApplicationFiled: November 4, 2011Publication date: March 1, 2012Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: John Chen, Raed Rizq, Kent Harrison, Daniel Horn, Gordon Kocur, Tracee Eidenschink, Ben Arcand, Derek Sutermeister, Jay Rassat, Colm McGuiness, Wendy Naimark, Ruth Cheng
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Publication number: 20120010589Abstract: The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.Type: ApplicationFiled: September 22, 2011Publication date: January 12, 2012Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Maria Palasis, Timothy J. Mickley, Toby Freyman, Wendy Naimark
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Patent number: 8038709Abstract: The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.Type: GrantFiled: January 30, 2008Date of Patent: October 18, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Timothy J. Mickley, Toby Freyman, Wendy Naimark
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Patent number: 7972295Abstract: Apparatus and method utilizing fluid to deliver a bolus of therapeutic material through a lumen to a delivery or discharge control portion of the apparatus, where the bolus may be discharged or delivered to a desired location.Type: GrantFiled: March 11, 2005Date of Patent: July 5, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Toby Freyman, Inas Khayal, Wendy Naimark
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Publication number: 20110130715Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.Type: ApplicationFiled: February 7, 2011Publication date: June 2, 2011Applicant: BOSTON SCIENTIFIC SCIMEDInventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein
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Patent number: 7951392Abstract: The present invention relates to microarray polymeric barriers designed to control the release rate of therapeutic agents. By varying the thickness of the coating or affecting, physically and/or chemically, the constituents of the barrier composition, the release profile of the underlying therapeutic agent can be modified and controlled.Type: GrantFiled: August 16, 2002Date of Patent: May 31, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Dennis R. Boulais, Maria Palasis, Samuel Epstein, Wendy Naimark
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Patent number: 7951402Abstract: A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.Type: GrantFiled: September 23, 2008Date of Patent: May 31, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Janel Lanphere, Erin McKenna, Wendy Naimark, Marcia Buiser, Stephan Mangin
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Patent number: 7938798Abstract: The present invention relates to a medical device and method for treating the body tissue of a patient. The present invention is also directed to a method of making the medical device and a method of using the medical device. More particularly, the invention relates to a medical device which is inserted into the body for delivery of therapeutic patches to the surface of a body lumen, organ or cavity. Specifically, the medical device has an umbrella-like or a basket-like expandable assembly; and a therapeutic patch. The expandable assembly is capable of changing from a retracted position to an expanded position. The expandable assembly can be self-expanding or non-self-expanding.Type: GrantFiled: January 26, 2009Date of Patent: May 10, 2011Inventors: Wendy Naimark, Maria Palasis
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Patent number: 7931932Abstract: A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in the presence of monomer; (b) contacting the reactive species with at least one monomer species, thereby forming a polymer coating on the surface of the medical device; and (c) providing at least one therapeutic agent within the polymer coating. The therapeutic agent may be incorporated during formation of the polymer coating or after formation of the polymer coating. The at least one reactive species can comprise, for example, a free radical species, a carbanion species, a carbocation species, a Ziegler-Natta polymerization complex, a metallocene complex, and/or an atom transfer radical polymerization initiator.Type: GrantFiled: February 14, 2008Date of Patent: April 26, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Robert A. Herrmann, Frederick H. Strickler, Wendy Naimark, Peter L. Dayton
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Patent number: 7892205Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.Type: GrantFiled: June 6, 2003Date of Patent: February 22, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein