Abstract: A method facilitates the assembly of a gas turbine engine. The method of assembly comprises providing a turbine nozzle including an inner band, an outer band, at least one vane extending between the inner and outer bands, and at least one leading edge fillet extending between the at least one vane and at least one of the inner and outer bands, wherein a leading edge of the at least one vane is downstream from the leading edges of the inner and outer bands, and coupling the turbine nozzle within the gas turbine engine such that the leading edge fillet is configured to facilitate minimizing vortex formation along the vane leading edge adjacent at least one of the inner and outer bands.

Abstract: In a first embodiment, implantable drainage devices with a curvilinear portion are provided, such as stents or drainage catheters formed as a tubular member having a curvilinear portion comprising one or more pairs of adjacent bends curved in opposite directions. The drainage devices house a drainage lumen that may extend through the curvilinear portion, which may be dimensioned to retain the drainage device within a body vessel and provide a desired fluid conductance through a tortuous portion of the drainage lumen within the curvilinear portion. The curvilinear portion may include two or more planar bends facing in opposite directions.

Abstract: An intraluminal device with controlled biodegradation is provided. The intraluminal device comprises a biodegradable tubular main body. An outer photodegradable layer is disposed over at least a portion of the intraluminal device. The photodegradable outer layer is chemically inert to the body fluids of the implanted region, thereby preventing premature biodegradation of the stent. Degradation of the outer photodegradable layer after a predetermined time occurs by irradiating the layer with UV light waves. After removal of the outer photodegradable layer, the tubular main body becomes exposed to its in vivo environment, thereby allowing biodegradation of the tubular main body.

Abstract: A stent and a method for implanting a stent for prophylactically protecting a duct are provided. The stent includes a non-expandable, generally tubular body having a proximal portion and a distal portion, a lumen extending through at least a portion of the body, a distal opening in the distal portion in fluid communication with the lumen and a proximal opening in the proximal portion in fluid communication with the lumen. The stent further includes a cap portion operably connected to the proximal portion of the body, the cap portion is movable between a non-expanded configuration and an expanded configuration. The non-expanded configuration has a reduced diameter to facilitate advancement into the patient and the expanded configuration has an expanded diameter configured to protect an opening of the internal bodily duct so as to prevent an unintentional entry of an elongate medical device through the opening and into the passageway of the internal bodily duct.

Abstract: A generally spherical vascular remodeling device is permanently positionable at a junction of afferent and efferent vessels of a bifurcation having an aneurysm. After positioning the device at the junction to substantially conform the device to the shape of the junction, the device acts as a scaffolding to inhibit herniation of objects out of the aneurysm and the device permits perfusion to the efferent vessels. Positioning the device may include deployment and mechanical or electrolytic release from a catheter. Embolic material may be inserted in the aneurysm before or after positioning the device. The device may have a first end, a second end substantially opposite to the first end, and a plurality of filaments extending between and coupled at the first end and the second end. Such devices may be football shaped, pumpkin shaped, or twisted. The device may include a plurality of loops forming a generally spherical shape.

Abstract: An implantable drainage device for treatment of a stricture of a body vessel is disclosed. The device comprises a drainage tube including an inlet and extending to an outlet to define a drainage lumen formed through the inlet and the outlet. The drainage tube includes a swell layer and a cast layer formed about the swell layer. The swell layer has a first agent dispersed thereabout for regulated drug elution through the cast layer. The cast layer has a second agent disposed thereabout for drug elution therefrom.

Abstract: A wire guide system and method of use are described. The wire guide system comprises a sheathing member, an elongate member, and a self-expandable expandable anchoring portion. The expandable anchoring portion is affixed to the distal end of the elongate member. Advancement of the wire guide system may be achieved by pre-loading the elongate member and the expandable anchoring portion into a lumen of the sheathing member. Upon reaching a target site within a body lumen, the sheathing member is proximally retracted so as to expose the expandable anchoring portion. Retraction of the sheathing member allows the expandable anchoring portion to radially self-expand and engage one or more walls of the body lumen so as to anchor the elongate wire in position. The elongate wire now provides a stabilized pathway for medical devices to be advanced thereover.

Abstract: A delivery system that is preloaded with a sleeve member and a metallic stent and method of delivery of the sleeve member and stent at a target stricture site are described. The method of delivery occurs in two stages. The first stage involves deployment of the sleeve member and the second stage involves deployment of the metallic stent within the interior region of the sleeve member. The sleeve member may be formed from a shape memory plastic which may also be biodegradable. The delivery system provides a method of deploying a covered stent that would not otherwise be possible because of limited introducer space.

Abstract: A medical device including a wire capture member such as, for example, a lithotripsy basket or a snare member, as well as a motion limiting means configured to limit a maximum expanded diameter of the wire capture member.

Abstract: In a first embodiment, implantable drainage devices with a curvilinear portion are provided, such as stents or drainage catheters formed as a tubular member having a curvilinear portion comprising one or more pairs of adjacent bends curved in opposite directions. The drainage devices house a drainage lumen that may extend through the curvilinear portion, which may be dimensioned to retain the drainage device within a body vessel and provide a desired fluid conductance through a tortuous portion of the drainage lumen within the curvilinear portion. The curvilinear portion may include two or more planar bends facing in opposite directions.

Abstract: The present invention provides apparatus and methods suitable for removing at least one stone in a body passage. The apparatus comprises a balloon catheter having at least one working lumen adapted to receive an extraction basket. In use, the extraction basket may be used to capture and remove relatively large stones, and/or crush relatively large stones into smaller stone fragments. The balloon may then be inflated and maneuvered to engage the stone fragments and urge at least one of the stone fragments out of the body passage.

Abstract: A method facilitates the assembly of a gas turbine engine. The method comprises providing a turbine nozzle including an inner band, an outer band, and at least one vane extending between the inner and outer bands, wherein the vane includes a first sidewall and a second sidewall connected together at a leading edge and a trailing edge and coupling the turbine nozzle to a combustor that includes a plurality of circumferentially-spaced cooling openings that are oriented with respect to the turbine nozzle such that cooling air discharged therefrom during engine operation is biased towards the vane leading edge.

Abstract: A gas turbine engine nozzle segment and process for producing such a nozzle segment to exhibit improved durability and aerodynamic performance. The process produces a nozzle segment having at least one vane between and interconnecting a pair of platforms. The nozzle segment is cast from a gamma prime-strengthened nickel-base superalloy, on whose surface is thermal sprayed an environmental coating formed of a MCrAlX-type coating material. The surface of the environmental coating is then worked to cause the coating to have a surface finish of less than 2.0 micrometers Ra. Cooling holes are then drilled in the nozzle segment, after which an oxidation-resistant coating is applied on the smoothed surface of the nozzle segment so as to maintain an outermost surface on the nozzle segment having surface finish of less than 2.0 micrometers Ra.

Abstract: A hybrid intraluminal device and a method for fabricating the device is described. The device has structural elements which have different properties. One portion of the device may contain a stent having a zigzag configuration. A second portion of the device may contain a stent having a braided configuration. The first and second portions may possess the same architectural pattern but yet exhibit variation in radial force as a result of various properties of the structural elements. The portions are attached to a coating to form a hybrid stent. Gaps between the different stent sections provide flexibility to the stent. The first and second portions may be configured in numerous ways. The structural features of the hybrid stent can be adapted to satisfy the criteria of specific medical applications.

Abstract: A gas turbine engine nozzle segment and process for producing such a nozzle segment to exhibit improved durability and aerodynamic performance. The process produces a nozzle segment having at least one vane between and interconnecting a pair of platforms. The nozzle segment is cast from a gamma prime-strengthened nickel-base superalloy, on whose surface is thermal sprayed an environmental coating formed of a MCrAlX-type coating material. The surface of the environmental coating is then worked to cause the coating to have a surface finish of less than 2.0 micrometers Ra. Cooling holes are then drilled in the nozzle segment, after which an oxidation-resistant coating is applied on the smoothed surface of the nozzle segment so as to maintain an outermost surface on the nozzle segment having surface finish of less than 2.0 micrometers Ra.

Abstract: A method facilitates the assembly of a gas turbine engine. The method comprises providing a turbine nozzle including an inner band, an outer band, and at least one vane extending between the inner and outer bands, wherein the vane includes a first sidewall and a second sidewall connected together at a leading edge and a trailing edge and coupling the turbine nozzle to a combustor that includes a plurality of circumferentially-spaced cooling openings that are oriented with respect to the turbine nozzle such that cooling air discharged therefrom during engine operation is biased towards the vane leading edge.

Abstract: A method facilitates the assembly of a gas turbine engine. The method of assembly comprises providing a turbine nozzle including an inner band, an outer band, at least one vane extending between the inner and outer bands, and at least one leading edge fillet extending between the at least one vane and at least one of the inner and outer bands, wherein a leading edge of the at least one vane is downstream from the leading edges of the inner and outer bands, and coupling the turbine nozzle within the gas turbine engine such that the leading edge fillet is configured to facilitate minimizing vortex formation along the vane leading edge adjacent at least one of the inner and outer bands.

Abstract: A method facilitates the assembly of a gas turbine engine. The method of assembly comprises providing a turbine nozzle including an inner band, an outer band, and at least one vane extending between the inner and outer bands, coupling the turbine nozzle within the gas turbine engine, such that the turbine nozzle is downstream from a combustor, and coupling the turbine nozzle to the combustor using at least a first annular ring, wherein the first annular ring substantially seals a gap defined between the turbine nozzle and the combustor.

Abstract: A turbine airfoil includes opposite pressure and suction sides extending in span from a flowpath surface. The flowpath surface has chordally opposite forward and aft edges and laterally opposite first and second endfaces corresponding with the airfoil pressure and suction sides. The flowpath surface joins the first endface at the forward edge in a forward bullnose and joins the second endface at the aft edge in an aft bullnose, with the bullnoses varying in radius from the opposite edges.

Abstract: A turbine nozzle includes a hollow vane joined to opposite inner and outer bands. The inner band includes a forward lip under the leading edge of the vane, an aft lip under the trailing edge of the vane, and a mounting flange spaced therebetween. An impingement bore extends obliquely and aft from the base of the mounting flange under a corner of the inner band toward the aft lip for impingement cooling thereof.