Patents by Inventor Wenhao Chen

Wenhao Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200381372
    Abstract: A physical unclonable functions (PUF) device including a first copper electrode, a second electrode, and a silicon oxide layer positioned directly between the first copper electrode and the second electrode; a method of producing a PUF device; an array comprising a PUF device; and a method of generating a secure key with a plurality of PUF devices.
    Type: Application
    Filed: March 23, 2018
    Publication date: December 3, 2020
    Inventors: Michael KOZICKI, Wenhao CHEN
  • Publication number: 20190370272
    Abstract: A method and apparatus for generating information are disclosed. An implementation of the method includes: receiving a target text, the target text including an objective and descriptive information of the objective; performing a dependency syntax parsing on the target text to generate a dependency tree of the target text; matching predetermined syntactic structure tree with the dependency treeto obtain at least one triple, a triple including a subject, a predicate, and an object; and determining, based on words contained in a triple among the at least one triple and a predetermined weight of the syntactic structure tree matched to obtain the triple, a target triple among the at least one triple.
    Type: Application
    Filed: March 15, 2019
    Publication date: December 5, 2019
    Inventors: Yuguang Chen, Lu Pan, Wenhao Chen, Hui Zhou, Weina Chen, Yuhong Zheng
  • Publication number: 20190370330
    Abstract: A method and an apparatus for event detection, a device, and a storage medium. An event is formed by acquiring a plurality of texts including a target keyword; extracting phrases independently describing event information from titles of the plurality of texts; and clustering the extracted phrases and gathering texts where phrases belonging to a same cluster are located to form an event. The accuracy of the event detection and the recall rate for an event can be improved through the method provided by embodiments of the present application.
    Type: Application
    Filed: April 3, 2019
    Publication date: December 5, 2019
    Inventors: YUGUANG CHEN, WENHAO CHEN, HUI ZHOU, YUHONG ZHENG, WEINA CHEN
  • Publication number: 20180361727
    Abstract: Embodiments disclosed herein represent powder based additive manufacturing processes which provide a microstructure having improved mechanical properties. The methods may include the use of ultrasonic excitation in combination with the active control of a substrate's temperature to provide some level of control over the microstructure and hence the properties.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 20, 2018
    Applicant: The Hong Kong University of Science and Technology
    Inventors: George Alexandru Tilita, Wenhao Chen, Chi Fong Kwan, Matthew Ming Fai Yuen
  • Patent number: 9675609
    Abstract: A pharmaceutical composition is provided having particles of a physical mixture that contain at least one 20-camptothecin or a derivative thereof, at least one surfactant, at least one stabilizer, and at least one diluent. The particles have a mean particle size of less than about 2500 nm. The pharmaceutical composition can be nano- or micro-sized particles containing the 20-camptothecin esters or derivatives thereof as part of a physical mixture, which can provide the active compound in a water-soluble/dispersible, bioavailable form. The particles can be used as an oral pharmaceutical composition which comprises the nano- or micro-sized form of 20-camptothecin esters or derivatives, such as in an oral suspension (e.g., an aqueous suspension), or capsules, or caplets. The pharmaceutical composition can be used in the treatment of a cancer or malignant tumor in a patient by oral administration thereof in a therapeutically effective amount.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: June 13, 2017
    Assignee: Cao Pharmaceuticals Inc.
    Inventors: Wenhao Chen, Jiyao Zhang, Zhisong Cao
  • Publication number: 20170128438
    Abstract: A pharmaceutical composition is provided having particles of a physical mixture that contain at least one 20-camptothecin or a derivative thereof, at least one surfactant, at least one stabilizer, and at least one diluent. The particles have a mean particle size of less than about 2500 nm. The pharmaceutical composition can be nano- or micro-sized particles containing the 20-camptothecin esters or derivatives thereof as part of a physical mixture, which can provide the active compound in a water-soluble/dispersible, bioavailable form. The particles can be used as an oral pharmaceutical composition which comprises the nano- or micro-sized form of 20-camptothecin esters or derivatives, such as in an oral suspension (e.g., an aqueous suspension), or capsules, or caplets. The pharmaceutical composition can be used in the treatment of a cancer or malignant tumor in a patient by oral administration thereof in a therapeutically effective amount.
    Type: Application
    Filed: November 11, 2015
    Publication date: May 11, 2017
    Inventors: Wenhao CHEN, Jiyao ZHANG, Zhisong CAO
  • Patent number: 9018006
    Abstract: The present invention provides materials and methods related to culturing stable Treg cells or in vivo expansion of stable Treg cells, the cells made by the methods, treatments for various inflammatory/autoimmune pathologies and transplant/graft rejection, and related materials. Ex vivo induction and expansion of the stable Tregs is described, including use of inducing compositions, such as certain mAbs and other compounds, along with expansion medium comprising IL-2. In vivo expansion of stable Treg cells and treatments for various inflammatory/autoimmune pathologies and transplant/graft rejection are described, including the use of mAbs and their variants.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: April 28, 2015
    Assignee: The University of Toledo
    Inventors: Stanislaw M. Stepkowski, Wenhao Chen, Yoshihiro Miyahara
  • Publication number: 20150026640
    Abstract: An information searching method and a terminal, which are related to the field of communications technologies, address a problem of operation inconvenience in an information searching process. The method includes displaying, after a user triggers a target letter in an alphabetical index area, information summarized by the target letter in an information display area. The alphabetical index area is used to display an alphabetical index and the information display area is used to display information to be searched for. The method also includes receiving a first specified operation triggered by the user and locking the information displayed in the information display area so that, after the information display area receives a page-turning operation triggered by the user, the information displayed in the information display area is switched only within a range of currently displayed information.
    Type: Application
    Filed: August 19, 2014
    Publication date: January 22, 2015
    Inventors: Konggang Wei, Haibo Shan, Wenhao Chen
  • Patent number: 8835376
    Abstract: A process for making particles for delivery of drug nanoparticles is disclosed herein. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, where the formed nanoparticles have a narrow particle size distribution; (b) providing an excipient to at least one of the precipitant solution, the anti-solvent solution and the suspension of drug nanoparticles, the excipient being selected to maintain said drug nanoparticles in a dispersed state when in liquid form; and (c) drying the suspension of drug nanoparticles containing the excipient therein to remove solvent therefrom, wherein removal of the solvent causes the excipient to solidify and thereby form micro-sized matrix particles, each micro-sized particle being comprised of drug nanoparticles dispersed in a solid matrix of the excipient.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: September 16, 2014
    Assignee: Nanomaterials Technology Pte Ltd
    Inventors: Zhigang Shen, Jimmy Sung Lai Yun, Jun Hu, Nital Arvind Jugade, Jiyao Zhang, Wenhao Chen, Zhe Wang, Lingyan Gao, William Glover, Jian Feng Chen
  • Publication number: 20140043942
    Abstract: A method and an apparatus can be used for identifying a posture. The method includes obtaining information about sending an ultrasonic wave by one or more ultrasonic transmitters and obtaining information about receiving the ultrasonic wave by ultrasonic receivers. The one or more ultrasonic transmitters are fixed on an object to be identified. The number of the one or more ultrasonic transmitters is at least one and the number of the ultrasonic receivers is at least three. A posture of the object to be identified can be identified according to the obtained information about sending an ultrasonic wave by one or more ultrasonic transmitters and information about receiving the ultrasonic wave by ultrasonic receivers.
    Type: Application
    Filed: July 30, 2013
    Publication date: February 13, 2014
    Inventors: Junteng Kang, Haibo Shan, Wenhao Chen
  • Patent number: 8631840
    Abstract: A kit for repairing and inflating inflatable items comprises a housing, a compressor assembly housed within the housing, a connecting device having an inlet connected to the compressor assembly and a seat adapted to be fluidically connected to a container assembly for a sealing liquid and to the inlet, a valve configured to be opened automatically when the container assembly is connected to the connection device and elastically maintained in a first position such as to fluidically disconnect the inlet from the seat when the container assembly is disconnected from the connecting device, and a flexible tube fluidically connected to the compressor assembly. In particular, the connecting device comprises an outlet fluidically connected to the valve so as to be fluidically connected to the inlet when the valve is in the first position, and in that the flexible tube is connected to the outlet.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: January 21, 2014
    Assignee: Tek Global S.r.l.
    Inventors: Sergio Lolli, Wenhao Chen
  • Publication number: 20130280208
    Abstract: The present invention provides materials and methods related to culturing stable Treg cells or in vivo expansion of stable Treg cells, the cells made by the methods, treatments for various inflammatory/autoimmune pathologies and transplant/graft rejection, and related materials. Ex vivo induction and expansion of the stable Tregs is described, including use of inducing compositions, such as certain mAbs and other compounds, along with expansion medium comprising IL-2. In vivo expansion of stable Treg cells and treatments for various inflammatory/autoimmune pathologies and transplant/graft rejection are described, including the use of mAbs and their variants.
    Type: Application
    Filed: July 25, 2011
    Publication date: October 24, 2013
    Applicant: University of Toledo
    Inventors: Stanislaw M. Stepkowski, Wenhao Chen, Yoshihiro Miyahara
  • Publication number: 20130199665
    Abstract: A kit for repairing and inflating inflatable items comprises a housing, a compressor assembly housed within the housing, a connecting device having an inlet connected to the compressor assembly and a seat adapted to be fluidically connected to a container assembly for a sealing liquid and to the inlet, a valve configured to be opened automatically when the container assembly is connected to the connection device and elastically maintained in a first position such as to fluidically disconnect the inlet from the seat when the container assembly is disconnected from the connecting device, and a flexible tube fluidically connected to the compressor assembly. In particular, the connecting device comprises an outlet fluidically connected to the valve so as to be fluidically connected to the inlet when the valve is in the first position, and in that the flexible tube is connected to the outlet.
    Type: Application
    Filed: April 7, 2011
    Publication date: August 8, 2013
    Applicant: TEK GLOBAL S.R.L.
    Inventors: Sergio Lolli, Wenhao Chen
  • Publication number: 20110306539
    Abstract: A process for making particles for delivery of drug nanoparticles is disclosed herein. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, where the formed nanoparticles have a narrow particle size distribution; (b) providing an excipient to at least one of the precipitant solution, the anti-solvent solution and the suspension of drug nanoparticles, the excipient being selected to maintain said drug nanoparticles in a dispersed state when in liquid form; and (c) drying the suspension of drug nanoparticles containing the excipient therein to remove solvent therefrom, wherein removal of the solvent causes the excipient to solidify and thereby form micro-sized matrix particles, each micro-sized particle being comprised of drug nanoparticles dispersed in a solid matrix of the excipient.
    Type: Application
    Filed: September 24, 2009
    Publication date: December 15, 2011
    Inventors: Zhigang Shen, Jimmy Sung Lai Yun, Jun Hu, Arvind Jugade, Jiyao Zhang, Wenhao Chen, Zhe Wang, Lingyan Gao, Jian Feng Chen
  • Patent number: 6251036
    Abstract: A carbon fiber arrow shaft comprises a hollow tube, a reinforced carbon fiber, and a resinoid binder. The hollow tube has a length between 500-900 mm, an inner diameter between 2-10 mm, and a tube wall thickness between 0.3-2 mm. The reinforced carbon fiber and the resinoid binder form a resin-impregnated carbon fiber. The carbon fiber arrow shaft is formed by directly and continuously winding the resin-impregnated carbon fiber around the hollow tube. The carbon fiber arrow shaft has a head section (L1), a middle section (L2) and a tail section (L3). A winding angle of the carbon fiber at the head section (L1) is changed from a larger winding angle to a smaller winding angle, a winding angle at the middle section (L2) stays constant, and a winding angle at the tail section (L3) is changed from a smaller winding angle to a larger winding angle. The lengths of the head section (L1) and the tail section (L3) are between 25-250 mm.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: June 26, 2001
    Assignee: Beijing Institute of Aeronautical Materials
    Inventors: Xiang Wu, Qingzhu Mao, Wenhao Chen, Dahai Sun, Minyong Liu, Weifang Chen