Patents by Inventor Wenheng Guo

Wenheng Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240125734
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.
    Type: Application
    Filed: April 24, 2023
    Publication date: April 18, 2024
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Patent number: 11644436
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: May 9, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Patent number: 11536734
    Abstract: A method and particle analyzer for measuring a low concentration particles sample disclosed.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: December 27, 2022
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Wenheng Guo, Baohua Yan, Tao Shen
  • Publication number: 20200232942
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 23, 2020
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Patent number: 10613051
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: April 7, 2020
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Publication number: 20190137528
    Abstract: A method and particle analyzer for measuring a low concentration particles sample disclosed.
    Type: Application
    Filed: August 2, 2018
    Publication date: May 9, 2019
    Inventors: Wenheng Guo, Baohua Yan, Tao Shen
  • Patent number: 10067150
    Abstract: A method and particle analyzer for measuring a low concentration particles sample disclosed.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: September 4, 2018
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Wenheng Guo, Baohua Yan, Tao Shen
  • Patent number: 9970857
    Abstract: This disclosure provides automatic compensation methods, corresponding devices and a corresponding flow cytometer. The automatic compensation method includes: determining a base cell population and a reference cell population in the cell populations according to positions of the cell populations in a dot plot that needs to be compensated, where the base cell population is a double negative cell population and the reference cell population is a single positive cell population adjacent to the base cell population in a compensating direction (S10); calculating automatically a compensation value through a progressive approximation algorithm according to a position of the base cell population, and updating the dot plot with the compensation value, so that the position difference between the reference cell population and the base cell population both in the dot plot in the compensating direction is within a predetermined range (S16).
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: May 15, 2018
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Penghao Liu, Wenheng Guo, Youlin Liu, Jian Jin, Huawen Yan, Lifang Dong
  • Publication number: 20170276642
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 28, 2017
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Patent number: 9714916
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. The method comprises: after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: July 25, 2017
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Publication number: 20170097296
    Abstract: This disclosure provides automatic compensation methods, corresponding devices and a corresponding flow cytometer. The automatic compensation method includes: determining a base cell population and a reference cell population in the cell populations according to positions of the cell populations in a dot plot that needs to be compensated, where the base cell population is a double negative cell population and the reference cell population is a single positive cell population adjacent to the base cell population in a compensating direction (S10); calculating automatically a compensation value through a progressive approximation algorithm according to a position of the base cell population, and updating the dot plot with the compensation value, so that the position difference between the reference cell population and the base cell population both in the dot plot in the compensating direction is within a predetermined range (S16).
    Type: Application
    Filed: October 10, 2016
    Publication date: April 6, 2017
    Inventors: Penghao LIU, Wenheng GUO, Youlin LIU, Jian JIN, Huawen YAN, Lifang DONG
  • Patent number: 9207159
    Abstract: A particle analyzer may include a sampling unit configured to collect samples containing particles; a sample preparing unit configured to prepare different sub-samples; a reaction unit configured to incubate the sub-samples and one or more corresponding reagents respectively and provide them to the injecting unit; an injecting unit configured to inject the sub-samples to the optical unit; an optical unit configured to irradiate the sub-samples to obtain particle information; a processing unit configured to process and output the particle information; and a threshold value unit configured to compare a total number of particles with a pre-determined threshold value and to output a result of the comparison to the injecting unit to control subsequent injection of one or more sub-samples.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: December 8, 2015
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Wenheng Guo, Jin Teng, Yingjian Zhan, Shuang Zhou, Huilin Shi
  • Patent number: 9170187
    Abstract: A flow cytometer and a fluid system are provided. The fluid system comprises a flow cell, a sample providing unit, a waste container, a sheath container, a negative pressure source, a quantitative unit and a sample flow monitoring unit, the negative pressure source, the waste container and the flow cell are connected, a negative pressure source, which provides a negative pressure relative to the sample providing unit for the flow cell so that the sample providing unit causes the sample to flow into the flow cell under the negative pressure, a sample flow monitoring unit monitors a flow of the sample fluid transported from the sample providing unit to the flow cell and outputs a feedback signal reflecting flow changes of the sample fluid in real-time; wherein the controller receives the feedback signal and controls the quantitative unit to adjust a flow of the sheath fluid according to the feedback signal.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: October 27, 2015
    Assignees: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD., BEIJING SHEN MINDRAY MEDICAL ELECTRONICS TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Baohua Yan, Chuixin Liao, William Li, Huawen Yan, Wenheng Guo
  • Publication number: 20150153263
    Abstract: A flow cytometer and a fluid system are provided. The fluid system comprises a flow cell, a sample providing unit, a waste container, a sheath container, a negative pressure source, a quantitative unit and a sample flow monitoring unit, the negative pressure source, the waste container and the flow cell are connected, a negative pressure source, which provides a negative pressure relative to the sample providing unit for the flow cell so that the sample providing unit causes the sample to flow into the flow cell under the negative pressure, a sample flow monitoring unit monitors a flow of the sample fluid transported from the sample providing unit to the flow cell and outputs a feedback signal reflecting flow changes of the sample fluid in real-time; wherein the controller receives the feedback signal and controls the quantitative unit to adjust a flow of the sheath fluid according to the feedback signal.
    Type: Application
    Filed: February 10, 2015
    Publication date: June 4, 2015
    Inventors: Baohua Yan, Chuixin Liao, William Li, Huawen Yan, Wenheng Guo
  • Publication number: 20140339101
    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. The method comprises: after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.
    Type: Application
    Filed: October 25, 2012
    Publication date: November 20, 2014
    Applicant: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
  • Patent number: 8720288
    Abstract: A counter assembly, sheath flow impedance count device, and flow cytometer analyzer are disclosed.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: May 13, 2014
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd
    Inventors: Tao Shen, Wenheng Guo, Jin Teng
  • Publication number: 20120171659
    Abstract: A particle analyzer may include a sampling unit configured to collect samples containing particles; a sample preparing unit configured to prepare different sub-samples; a reaction unit configured to incubate the sub-samples and one or more corresponding reagents respectively and provide them to the injecting unit; an injecting unit configured to inject the sub-samples to the optical unit; an optical unit configured to irradiate the sub-samples to obtain particle information; a processing unit configured to process and output the particle information; and a threshold value unit configured to compare a total number of particles with a pre-determined threshold value and to output a result of the comparison to the injecting unit to control subsequent injection of one or more sub-samples.
    Type: Application
    Filed: December 14, 2011
    Publication date: July 5, 2012
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Wenheng Guo, Jin Teng, Yingjian Zhan, Shuang Zhou, Huilin Shi
  • Publication number: 20120160017
    Abstract: A counter assembly, sheath flow impedance count device, and flow cytometer analyzer are disclosed.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 28, 2012
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Tao Shen, Wenheng Guo, Jin Teng