Patents by Inventor Wenheng Guo
Wenheng Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240125734Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.Type: ApplicationFiled: April 24, 2023Publication date: April 18, 2024Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Patent number: 11644436Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.Type: GrantFiled: March 26, 2020Date of Patent: May 9, 2023Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Patent number: 11536734Abstract: A method and particle analyzer for measuring a low concentration particles sample disclosed.Type: GrantFiled: August 2, 2018Date of Patent: December 27, 2022Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Wenheng Guo, Baohua Yan, Tao Shen
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Publication number: 20200232942Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.Type: ApplicationFiled: March 26, 2020Publication date: July 23, 2020Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Patent number: 10613051Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.Type: GrantFiled: May 23, 2017Date of Patent: April 7, 2020Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Publication number: 20190137528Abstract: A method and particle analyzer for measuring a low concentration particles sample disclosed.Type: ApplicationFiled: August 2, 2018Publication date: May 9, 2019Inventors: Wenheng Guo, Baohua Yan, Tao Shen
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Patent number: 10067150Abstract: A method and particle analyzer for measuring a low concentration particles sample disclosed.Type: GrantFiled: December 28, 2011Date of Patent: September 4, 2018Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Wenheng Guo, Baohua Yan, Tao Shen
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Patent number: 9970857Abstract: This disclosure provides automatic compensation methods, corresponding devices and a corresponding flow cytometer. The automatic compensation method includes: determining a base cell population and a reference cell population in the cell populations according to positions of the cell populations in a dot plot that needs to be compensated, where the base cell population is a double negative cell population and the reference cell population is a single positive cell population adjacent to the base cell population in a compensating direction (S10); calculating automatically a compensation value through a progressive approximation algorithm according to a position of the base cell population, and updating the dot plot with the compensation value, so that the position difference between the reference cell population and the base cell population both in the dot plot in the compensating direction is within a predetermined range (S16).Type: GrantFiled: October 10, 2016Date of Patent: May 15, 2018Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Penghao Liu, Wenheng Guo, Youlin Liu, Jian Jin, Huawen Yan, Lifang Dong
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Publication number: 20170276642Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.Type: ApplicationFiled: May 23, 2017Publication date: September 28, 2017Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Patent number: 9714916Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. The method comprises: after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.Type: GrantFiled: October 25, 2012Date of Patent: July 25, 2017Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Publication number: 20170097296Abstract: This disclosure provides automatic compensation methods, corresponding devices and a corresponding flow cytometer. The automatic compensation method includes: determining a base cell population and a reference cell population in the cell populations according to positions of the cell populations in a dot plot that needs to be compensated, where the base cell population is a double negative cell population and the reference cell population is a single positive cell population adjacent to the base cell population in a compensating direction (S10); calculating automatically a compensation value through a progressive approximation algorithm according to a position of the base cell population, and updating the dot plot with the compensation value, so that the position difference between the reference cell population and the base cell population both in the dot plot in the compensating direction is within a predetermined range (S16).Type: ApplicationFiled: October 10, 2016Publication date: April 6, 2017Inventors: Penghao LIU, Wenheng GUO, Youlin LIU, Jian JIN, Huawen YAN, Lifang DONG
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Patent number: 9207159Abstract: A particle analyzer may include a sampling unit configured to collect samples containing particles; a sample preparing unit configured to prepare different sub-samples; a reaction unit configured to incubate the sub-samples and one or more corresponding reagents respectively and provide them to the injecting unit; an injecting unit configured to inject the sub-samples to the optical unit; an optical unit configured to irradiate the sub-samples to obtain particle information; a processing unit configured to process and output the particle information; and a threshold value unit configured to compare a total number of particles with a pre-determined threshold value and to output a result of the comparison to the injecting unit to control subsequent injection of one or more sub-samples.Type: GrantFiled: December 14, 2011Date of Patent: December 8, 2015Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Wenheng Guo, Jin Teng, Yingjian Zhan, Shuang Zhou, Huilin Shi
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Patent number: 9170187Abstract: A flow cytometer and a fluid system are provided. The fluid system comprises a flow cell, a sample providing unit, a waste container, a sheath container, a negative pressure source, a quantitative unit and a sample flow monitoring unit, the negative pressure source, the waste container and the flow cell are connected, a negative pressure source, which provides a negative pressure relative to the sample providing unit for the flow cell so that the sample providing unit causes the sample to flow into the flow cell under the negative pressure, a sample flow monitoring unit monitors a flow of the sample fluid transported from the sample providing unit to the flow cell and outputs a feedback signal reflecting flow changes of the sample fluid in real-time; wherein the controller receives the feedback signal and controls the quantitative unit to adjust a flow of the sheath fluid according to the feedback signal.Type: GrantFiled: February 10, 2015Date of Patent: October 27, 2015Assignees: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD., BEIJING SHEN MINDRAY MEDICAL ELECTRONICS TECHNOLOGY RESEARCH INSTITUTE CO., LTD.Inventors: Baohua Yan, Chuixin Liao, William Li, Huawen Yan, Wenheng Guo
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Publication number: 20150153263Abstract: A flow cytometer and a fluid system are provided. The fluid system comprises a flow cell, a sample providing unit, a waste container, a sheath container, a negative pressure source, a quantitative unit and a sample flow monitoring unit, the negative pressure source, the waste container and the flow cell are connected, a negative pressure source, which provides a negative pressure relative to the sample providing unit for the flow cell so that the sample providing unit causes the sample to flow into the flow cell under the negative pressure, a sample flow monitoring unit monitors a flow of the sample fluid transported from the sample providing unit to the flow cell and outputs a feedback signal reflecting flow changes of the sample fluid in real-time; wherein the controller receives the feedback signal and controls the quantitative unit to adjust a flow of the sheath fluid according to the feedback signal.Type: ApplicationFiled: February 10, 2015Publication date: June 4, 2015Inventors: Baohua Yan, Chuixin Liao, William Li, Huawen Yan, Wenheng Guo
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Publication number: 20140339101Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. The method comprises: after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.Type: ApplicationFiled: October 25, 2012Publication date: November 20, 2014Applicant: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Tao Shen, Huilin Shi, Jin Teng, Wenheng Guo
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Patent number: 8720288Abstract: A counter assembly, sheath flow impedance count device, and flow cytometer analyzer are disclosed.Type: GrantFiled: December 22, 2011Date of Patent: May 13, 2014Assignee: Shenzhen Mindray Bio-Medical Electronics Co., LtdInventors: Tao Shen, Wenheng Guo, Jin Teng
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Publication number: 20120171659Abstract: A particle analyzer may include a sampling unit configured to collect samples containing particles; a sample preparing unit configured to prepare different sub-samples; a reaction unit configured to incubate the sub-samples and one or more corresponding reagents respectively and provide them to the injecting unit; an injecting unit configured to inject the sub-samples to the optical unit; an optical unit configured to irradiate the sub-samples to obtain particle information; a processing unit configured to process and output the particle information; and a threshold value unit configured to compare a total number of particles with a pre-determined threshold value and to output a result of the comparison to the injecting unit to control subsequent injection of one or more sub-samples.Type: ApplicationFiled: December 14, 2011Publication date: July 5, 2012Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Wenheng Guo, Jin Teng, Yingjian Zhan, Shuang Zhou, Huilin Shi
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Publication number: 20120160017Abstract: A counter assembly, sheath flow impedance count device, and flow cytometer analyzer are disclosed.Type: ApplicationFiled: December 22, 2011Publication date: June 28, 2012Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Tao Shen, Wenheng Guo, Jin Teng