Patents by Inventor Wen-Hua Fan

Wen-Hua Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110287415
    Abstract: The present invention provides probes, kits and methods for specifically binding mRNA of target cells, e.g., fetal cells, that allows visualization of the target cells, under conditions that allows a second probe to specifically bind the target cell's chromosomal DNA.
    Type: Application
    Filed: August 4, 2008
    Publication date: November 24, 2011
    Applicant: Novartis AG
    Inventors: Wen-Hua Fan, Roger Tim, Ram Bhatt
  • Publication number: 20110262916
    Abstract: The present invention discloses methods of determining the RhD genotype of subject. In particular, the invention provides a non-invasive method of determining fetal RhD genotype from a maternal biological sample containing fetal cells. The invention also provides novel probes and primers useful in the described methods. Kits and mixtures comprising the novel probes and primers are also disclosed.
    Type: Application
    Filed: July 17, 2009
    Publication date: October 27, 2011
    Inventors: Wen-Hua Fan, Roger Tim, Karena Kosco, Ram Bhatt
  • Publication number: 20110171640
    Abstract: The present invention provides methods for isolating cell free nucleic acid, e.g., apoptotic or fetal nucleic acids and methods of detecting neoplastic cells or identifying the genetic composition of a fetus. The invention also provides magnetic particles comprising an anti-DNA antibody, and kits comprising the magnetic particles.
    Type: Application
    Filed: February 6, 2009
    Publication date: July 14, 2011
    Applicant: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Ram Bhatt, Wen-Hua Fan
  • Publication number: 20110143340
    Abstract: The present invention provides compositions comprising a solution of a compound useful for lysing biological cells and methods for using the compositions to lyse biological cells and to isolate nucleic acid.
    Type: Application
    Filed: October 30, 2008
    Publication date: June 16, 2011
    Applicant: BIOCEPT, INC.
    Inventors: Wen-Hua Fan, Irene Yasuda, Karena Kosco, Ram Bhatt
  • Publication number: 20100261188
    Abstract: The present invention provides methods and kits useful for genetic testing or screening of fetuses using nucleic acid samples isolated from cervical mucus samples of fetus hosts.
    Type: Application
    Filed: April 27, 2010
    Publication date: October 14, 2010
    Applicant: BIOCEPT, INC.
    Inventors: Ram Bhatt, Wen-Hua Fan, Roger Tim, Farideh Z. Bischoff
  • Publication number: 20080176237
    Abstract: The present invention provides methods and kits useful for genetic testing or screening of fetuses using nucleic acid samples isolated from cervical mucus samples of fetus hosts.
    Type: Application
    Filed: December 7, 2007
    Publication date: July 24, 2008
    Applicant: BIOCEPT, INC.
    Inventors: Ram Bhatt, Wen-Hua Fan, Roger Tim, Farideh Z. Bischoff
  • Publication number: 20080050842
    Abstract: A method and kit are provided for visualization of a latent pattern of molecular structures on a substrate surface. The method is comprised of exposing the substrate to a solution of nano-particles or to a powder of nano-particles. A detectable change is brought about as a result of non-specific binding nano-particles to the chemical groups on the substrate surface carrying the target molecular structures. The invention also provides compositions and kit for practicing the method. Further, the invention provides methods of capturing image of the substrate surface for visualization and quantitation of the molecular structures.
    Type: Application
    Filed: October 20, 2006
    Publication date: February 28, 2008
    Inventors: Valeri Golovlev, Ye Sun, Michael McCann, Wen-Hua Fan
  • Publication number: 20040161862
    Abstract: A method and kit are provided for visualization of a latent pattern of molecular structures on a substrate surface. The method is comprised of developing the substrate in a solution of colloidal particles. A detectable change on the substrate surface is brought about as a result of the precipitation of the colloidal particles. The invention also provides compositions and kits for practicing the method of the present invention. Further, the invention provides methods of capturing images of the substrate surface for visualization and quantification of the molecular structures.
    Type: Application
    Filed: February 11, 2004
    Publication date: August 19, 2004
    Inventors: Valeri V. Golovlev, Ye Sun, Michael P. McCann, Wen-Hua Fan