Patents by Inventor Wenhui Fu

Wenhui Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240102025
    Abstract: The present disclosure provides a gene combination for expressing and producing terrequinone A in Escherichia coli and use thereof. The gene combination includes a tdiAS gene, a tdiBS gene, a tdiCS gene, a tdiDS gene, a tdiES gene, an sfpS gene, an ScCKS gene, and an AtIPKS gene with nucleotide sequences set forth in SEQ ID NOS:1 to 8. In the present disclosure, a recombinant engineered strain capable of producing terrequinone A having anti-cancer activity is obtained by separately constructing recombinant plasmids pC02 and pU03 through the eight genes and transforming the two recombinant plasmids into E. coli. The content of terrequinone A in a fermentation broth thereof is 106.3 mg/L, which has potential application value in the biopharmaceutical field.
    Type: Application
    Filed: May 24, 2023
    Publication date: March 28, 2024
    Inventors: Yongsheng TIAN, Lijuan WANG, Yongdong DENG, Quanhong YAO, Rihe PENG, Jianjie GAO, Zhenjun LI, Wenhui ZHANG, Bo WANG, Jing XU, Yu WANG, Xiaoyan FU, Hongjuan HAN
  • Patent number: 6858233
    Abstract: The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonaceous adsorbent, such as activated carbon, to obtain a mixture, separating the adsorbent from the mixture to obtain a purified liquid extract, and drying the purified liquid extract.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: February 22, 2005
    Assignee: International Flora Technologies, Ltd.
    Inventors: Qingnong Tang, James Howard Brown, Wenhui Fu
  • Publication number: 20040037908
    Abstract: The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonaceous adsorbent, such as activated carbon, to obtain a mixture, separating the adsorbent from the mixture to obtain a purified liquid extract, and drying the purified liquid extract.
    Type: Application
    Filed: July 3, 2003
    Publication date: February 26, 2004
    Applicant: International Flora Technologies, Ltd.
    Inventors: Qingnong Tang, James Howard Brown, Wenhui Fu
  • Patent number: 6620442
    Abstract: The invention provides a process for reducing odor, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonaceous adsorbent, such as activated carbon, to obtain a mixture, separating the adsorbent from the mixture to obtain a purified liquid extract, and drying the purified liquid extract.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: September 16, 2003
    Assignee: International Flora Technologies, Inc.
    Inventors: Qingnong Tang, James Howard Brown, Wenhui Fu
  • Publication number: 20030044477
    Abstract: The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonaceous adsorbent, such as activated carbon, to obtain a mixture, separating the adsorbent from the mixture to obtain a purified liquid extract, and drying the purified liquid extract.
    Type: Application
    Filed: August 24, 2001
    Publication date: March 6, 2003
    Inventors: Qingnong Tang, James Howard Brown, Wenhui Fu