Patents by Inventor Wenzhi Xue

Wenzhi Xue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF GABAA RECEPTOR AS TARGET IN PREPARATION OR SCREENING OF DRUG FOR LOWERING BLOOD LIPID LEVEL, TREATING OBESITY, AND/OR IMPROVING METABOLISM
    Publication number: 20240173344
    Abstract: The present disclosure belongs to the technical field of medicine, and relates to a use of a GABAA receptor as a target in the preparation or screening of a drug for reducing blood lipid, treating obesity, and/or improving metabolism. The present disclosure provides a use of a GABAA receptor as a target in the preparation or screening of a drug with one or more functions selected from the group consisting of functions (1) to (4): (1) reducing blood lipid; (2) treating obesity; (3) improving metabolic syndrome; and (4) inhibiting small intestinal lipid absorption. The GABAA receptor is closely related to a lipid absorption ability of a small intestine, and the use of the present disclosure provides a new drug target and a new therapeutic means for treating obesity, reducing blood lipid, and improving metabolism.
    Type: Application
    Filed: March 28, 2023
    Publication date: May 30, 2024
    Applicants: SHANGHAI INSTITUTE OF ENDOCRINE AND METABOLIC DISEASES, RUIJIN HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Guang NING, Jiqiu WANG, Qianqian LYU, Wenzhi XUE, Ruixin LIU
  • Attenuated bovine coronavirus and related vaccines
    Patent number: 10434168
    Abstract: The present invention discloses novel attenuated bovine coronavirus isolates, compositions comprising these isolate, and methods of using such compositions in vaccines, including in live vaccines. The present invention further discloses the administration of such vaccines, including the intranasal administration of such vaccines, to aid in the prevention of respiratory disease caused by bovine coronavirus.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: October 8, 2019
    Assignee: Intervet Inc.
    Inventors: Catherine M. Peters, Mark W. Mellencamp, Wenzhi Xue, Terri Wasmoen, Emilio Trigo
  • ATTENUATED BOVINE CORONAVIRUS AND RELATED VACCINES
    Publication number: 20170274065
    Abstract: The present invention discloses novel attenuated bovine coronavirus isolates, compositions comprising these isolate, and methods of using such compositions in vaccines, including in live vaccines. The present invention further discloses the administration of such vaccines, including the intranasal administration of such vaccines, to aid in the prevention of respiratory disease caused by bovine coronavirus.
    Type: Application
    Filed: September 2, 2015
    Publication date: September 28, 2017
    Applicant: Intervet Inc.
    Inventors: Catherine M. Peters, Mark W. Mellencamp, Wenzhi Xue, Terri Wasmoen, Emilio Trigo