Abstract: A crankcase of an internal combustion engine with at least one main lubricant channel for supplying the internal combustion engine with lubricant and with at least one oil return flow channel (10) for return guidance of the excess lubricant into a reservoir container (11), wherein the oil return flow channel (10) exhibits a peg-shaped widening (12), which is formed by the attachment a bearing support of an oil channel core (18). The invention further concerns an oil channel core.

Abstract: A crankcase of an internal combustion engine with at least one main lubricant channel for supplying the internal combustion engine with lubricant and with at least one oil return flow channel (10) for return guidance of the excess lubricant into a reservoir container (11), wherein the oil return flow channel (10) exhibits a peg-shaped widening (12), which is formed by the attachment a bearing support of an oil channel core (18). The invention further concerns an oil channel core.

Abstract: In a balance shaft for a multi-cylinder in-line engine with at least two imbalance weight sections and at least one bearing structure wherein the balance shaft has imbalance weight sections being arranged symmetrically relative to the bearing position and at least one of the imbalance weight sections is connected to a further shaft section at an end facing away from the bearing position, a flexible coupling element that enables a deflection of the end of the connected imbalance weight section in the direction of the resulting centrifugal forces when the balance shaft rotates is provided between the end of the at least one imbalance weight section facing away from the bearing position and the further shaft section.

Abstract: A crankcase of an internal combustion engine with at least one main lubricant channel for supplying the internal combustion engine with lubricant and with at least one oil return flow channel (10) for return guidance of the excess lubricant into a reservoir container (11), wherein the oil return flow channel (10) exhibits a peg-shaped widening (12), which is formed by the attachment a bearing support of an oil channel core (18). An oil channel core as well as a process for producing a crankcase.

Abstract: In a balance shaft for a multi-cylinder in-line engine with at least two imbalance weight sections and at least one bearing structure wherein the balance shaft has imbalance weight sections being arranged symmetrically relative to the bearing position and at least one of the imbalance weight sections is connected to a further shaft section at an end facing away from the bearing position, a flexible coupling element that enables a deflection of the end of the connected imbalance weight section in the direction of the resulting centrifugal forces when the balance shaft rotates is provided between the end of the at least one imbalance weight section facing away from the bearing position and the further shaft section.

Abstract: A crankcase of an internal combustion engine with at least one main lubricant channel for supplying the internal combustion engine with lubricant and with at least one oil return flow channel (10) for return guidance of the excess lubricant into a reservoir container (11), wherein the oil return flow channel (10) exhibits a peg-shaped widening (12), which is formed by the attachment a bearing support of an oil channel core (18). An oil channel core as well as a process for producing a crankcase.

Abstract: The invention relates to novel quinoline derivatives and their therapeutic use against malaria.

Abstract: In an internal combustion engine including a cylinder head and at least one camshaft and accessory units comprising pumps mounted on the front end of the engine on which also drive means for the camshaft of camshafts are disposed, the accessory units are operatively coupled to the drive means for the camshafts or camshafts so as to be driven thereby.

Abstract: A cylinder head cover for a direct-injecting internal-combustion engine has an injection nozzle holder arranged in the cylinder head between charge cycle valves and a clamping shoe for fixing the position of the injection nozzle holder in a receiving bore in the cylinder head. The cylinder head cover is constructed to be pulled in in the area of the injection nozzle holder and has a passage for the injection nozzle holder. The pulled-in cylinder head cover in the area of the injection nozzle holder is pulled down to the cylinder head. Starting from that area, a drainage-groove-type indentation leads to the inlet side of the internal-combustion engine.

Abstract: Disclosed are N,N'-bis(quinolin-4-yl)diamine derivatives of general formula I wherein R.sup.1 signifies halogen or trifluoromethyl, R.sup.2 signifies hydrogen or halogen, A signifies cyclohexane-1,3-diyl, 2-methyl-cyclohexane-1,3-diyl, cyclohexane-1,4-diyl, dicyclohexylmethane-4,4'-diyl, cyclopentane-1,3-diyl, phenylene-1,4, phenylene-1,3 and phenylene-1,2; n is 1 or 2; m is 1 or 2, as well as their pharmaceutically acceptable salts. These products are useful as agents for preventing malaria and for treating it, especially where the pathogens are resistant to chloroquine.

Abstract: Novel aminoquinoline derivatives of the general formula ##STR1## are described. Also described are methods for the treatment of malaria pathogens, particularly chloroquine-resistance malaria pathogens with compounds of formula I or the pharmaceutically acceptable salts and hydrolyzable esters thereof.

Abstract: A novel process for the asymmetric hydrogenation of compounds of the formula: ##STR1## wherein R represent aryl or heteroaryl, to compounds of the formula: ##STR2## wherein R has the above significance, is carried out using rhodium-diphosphine complexes.

Abstract: Cephalosporin derivatives have the formula ##STR1## wherein Z.sup.1, Z.sup.2, X, Y, P, Q, m, n and p are as defined in the following text. Also described are the readily hydrolyzable esters and pharmaceutically compatible salts of these compounds, and hydrates of compounds of formula I, their esters and salts. Processes are provided for manufacture and pharmaceutical preparations which contain these compounds. Intermediates from the manufacture of these compounds are described, as is the use of the compounds in the control of illnesses and for the manufacture of the aforementioned preparations.

Abstract: Novel 4-substituted-4,8-dimethyl-2,3-dioxabicyclo[3.3.1] nonan-7-ones which have a pronounced activity against the causative organism of malaria and can be used for the prevention and control of malaria.

Abstract: Acyl derivatives of the formula ##STR1## in which R is an acyl group, excluding those acyl groups of the formula ##STR2## in which A is a group of the formulae --NHCO--, --NHCONHCO--, --NHCOCH.dbd.CH--, ##STR3## wherein R.sup.6 is hydrogen or lower alkyl; R.sup.1 and R.sup.2 are hydrogen or a protecting group, X is hydrogen, halogen, lower alkoxy, nitro or --OR.sup.2, n is 1 or 2, R.sup.4 and R.sup.5 are hydrogen or together represent an additional bond and Z is a direct bond or carbonyl (where R.sup.4 and R.sup.5 both represent hydrogen) or a group of the formula --O--B-- (where R.sup.4 and R.sup.5 together represent an additional bond) in which B is a straight-chain, branched or cyclic lower alkylene;and wherein R.sup.3 is a substituted bicyclic group of the formulae ##STR4## wherein R.sup.7 and R.sup.

Abstract: Novel 4-substituted-4,8-dimethyl-2,3-dioxabicyclo[3.3.1] nonan-7-ones which have a pronounced activity against the causative organism of malaria and can be used for the prevention and control of malaria.

Abstract: The manufacture of 1-sulpho-2-oxazetidine derivatives of the formula ##STR1## in which Het is an optionally amino-substituted, 5- or 6-membered, aromatic heterocycle containing 1 or 2 nitrogen atoms and optionally also an oxygen or sulphur atom, R.sup.1 is hydrogen, lower alkyl, phenyl-lower alkyl, lower alkanoyl, lower alkoxycarbonyl, lower alkenyl-lower alkyl, lower alkoxycarbonyl-lower alkyl, phenyl-lower-alkoxycarbonyl-lower alkyl, nitrophenyl-lower-alkoxycarbonyl-lower alkyl or carboxy-lower alkyl and R.sup.2 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxycarbonyl, lower alkanoyloxy-lower alkyl, lower alkoxycarbonyl-lower alkenyl, hydroxyiminomethyl, lower alkoxyiminomethyl, carbamoyl, carbamoyl-lower alkenyl or carbamoyloxy-lower alkyl, the group .dbd.NOR.sup.

Abstract: Antimicrobial 2-oxo-1-azetidinesulphonic acids of the formula ##STR1## in which H.sub.2 N ##STR2## represents an amino-substituted thiazolyl group, R.sup.1 is lower alkyl which is substituted by carbamoyl, lower alkylsuphonyl, azido, piperidine-carbonyl, (hexahydro-1H-azepin-1-yl)carbonyl or lower alkynyl, and R.sup.2 is hydrogen or a lower organic group, typically, carbamoyloxymethyl.

Abstract: The manufacture of 1-sulpho-2-oxazetidine derivatives of the formula ##STR1## in which Het is an optionally amino-substituted, 5- or 6-membered, aromatic heterocycle containing 1 or 2 nitrogen atoms and optionally also an oxygen or sulphur atom, R.sup.1 is hydrogen, lower alkyl, phenyl-lower alkyl, lower alkanoyl, lower alkoxycarbonyl, lower alkenyl-lower alkyl, lower alkoxycarbonyl-lower alkyl, phenyl-lower-alkoxycarbonyl-lower alkyl, nitrophenyl-lower-alkoxycarbonyl-lower alkyl or carboxy-lower alkyl and R.sup.2 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxycarbonyl, lower alkanoyloxy-lower alkyl, lower alkoxycarbonyl-lower alkenyl, hydroxyiminomethyl, lower alkoxyiminomethyl, carbamoyl, carbamoyl-lower alkenyl or carbamoyloxy-lower alkyl, the group .dbd.NOR.sup.

Abstract: 2-Nitroimidazoles having protozoocidal activity of the formula ##STR1## wherein R.sup.1 is 1-methyl-2-pyrrolidinyl or a group --CH.sub.2 -- NR.sup.2 R.sup.3 in which R.sup.2 and R.sup.3 each represent C.sub.1-4 -alkyl or --NR.sup.2 R.sup.3 is the residue of a five-membered or six-membered saturated heterocyclic ring system which optionally contains an additional nitrogen or oxygen atom in the ring, physiologically acceptable acid addition salts thereof, processes for their preparation, and pharmaceutical compositions containing these compounds are described.