Abstract: The present invention relates to methods for diagnosing, staging and treating cancer, in particular melanoma. In particular, the present invention provides methods for determining the stage/type of a cancerous disease, comprising detecting somatic alterations of the DNA of one or more disseminated cancer cells (DCCs), obtained after homing to a distant organ, such as lymph node; and determining the somatic evolution of the DCC(s) based on the detected somatic alterations, wherein the somatic evolution is indicative of the stage/type of the cancerous disease.

Abstract: The present invention relates to methods for diagnosing, staging and treating cancer, in particular melanoma. In particular, the present invention provides methods for determining the stage/type of a cancerous disease, comprising detecting somatic alterations of the DNA of one or more disseminated cancer cells (DCCs), obtained after homing to a distant organ, such as lymph node; and determining the somatic evolution of the DCC(s) based on the detected somatic alterations, wherein the somatic evolution is indicative of the stage/type of the cancerous disease.

Abstract: The invention relates to a method for tracing bank notes, wherein bank notes are inserted into an automated teller machine having a deposit function and are checked for authenticity, wherein a serial number of the bank note is detected and is stored as text together with transaction data. In addition, a serial number image of the bank notes is detected which forms an image detail of the bank note in an area of the bank note intended for the serial number, the detected serial number image with the serial number and the transaction data are stored and the serial number images are compared with the forged bank note if the serial number of the forged bank note has not been completely identified and/or if a comparison of the serial number of the forged bank note does not produce an agreement with the at least one stored serial number.

Abstract: The invention relates to a method for tracing bank notes, wherein bank notes are inserted into an automated teller machine having a deposit function and are checked for authenticity, wherein a serial number of the bank note is detected and is stored as text together with transaction data. In addition, a serial number image of the bank notes is detected which forms an image detail of the bank note in an area of the bank note intended for the serial number, the detected serial number image with the serial number and the transaction data are stored and the serial number images are compared with the forged bank note if the serial number of the forged bank note has not been completely identified and/or if a comparison of the serial number of the forged bank note does not produce an agreement with the at least one stored serial number.

Abstract: In a multi-disk clutch comprising a rotary body having splines formed thereon so as to extend helically along the surface thereof, with a number of disks having central openings with inwardly projecting teeth via which the discs are in rotationally positively locking engagement with the rotary body, the teeth are twisted so as to extend in a plane normal to the surface of the helically extending splines of the rotary body so that the end face areas of the teeth are in planar contact with the spline surfaces of the rotary body for the transmission of torque between the rotary body and the disks.

Abstract: In an all-wheel drive train for a motor vehicle wherein the drive torque of the engine of the motor vehicle is transmitted from the transmission output shaft partially to the rear axle and partially to the front axle via an offset transmission structure and a laterally arranged drive shaft extending from the offset transmission structure past the transmission to the front axle of the motor vehicle extends from the offset transmission forwardly at a certain opening angle in close proximity to the transmission structure which narrows down toward the rear so that the rear end of the lateral drive shaft is relatively close to the center axis of the transmission.

Abstract: In an all-wheel drive train for a motor vehicle wherein the drive torque of the engine of the motor vehicle is transmitted from the transmission output shaft partially to the rear axle and partially to the front axle via an offset transmission structure and a laterally arranged drive shaft extending from the offset transmission structure past the transmission to the front axle of the motor vehicle extends from the offset transmission forwardly at a certain opening angle in close proximity to the transmission structure which narrows down toward the rear so that the rear end of the lateral drive shaft is relatively close to the center axis of the transmission.

Abstract: In a multi-disk clutch comprising a rotary body having splines formed thereon so as to extend helically along the surface thereof, with a number of disks having central openings with inwardly projecting teeth via which the discs are in rotationally positively locking engagement with the rotary body, the teeth are twisted so as to extend in a plane normal to the surface of the helically extending splines of the rotary body so that the end face areas of the teeth are in planar contact with the spline surfaces of the rotary body for the transmission of torque between the rotary body and the disks.

Abstract: In a longitudinally installed four wheel drive train of a motor which includes a front drive shaft, which transmits the engine driving torque to the front axle from the rear end of the vehicle transmission the front drive shaft comprises at least at its rear end two opposite radially projecting pins extending into longitudinal grooves formed in a gear wheel of a front drive structure so as to be axially movably and pivotally supported therein.

Abstract: The present invention relates to a method for determining the enantioselectivity of kinetic resolution processes and of asymmetrically proceeding reactions of prochiral compounds bearing enantiotopic groups by using isotope-labeled substrates so that the reaction products can be quantitatively determined with an isotope-specific detection system, e.g., an ESI mass spectrometer. In connection with automated sample charging, the method can be employed for high throughput screening. The relevant enantioselective conversions can be induced by chiral homogeneous or heterogeneous catalysts, biocatalysts or stoichiometric amounts of optically active agents.

Abstract: There is described a travelling multi-functional disposal simulation instation for simulating the long-term behaviour of materials for disposal containing organic components. These can comprise disposable house refuse and similar wastes, but also contaminated soils. Simulation serves for recultivation, composing and similar soil investigations. The installation constructed for this purpose comprises a double-walled heatable container, a lower, inner base plate with a slight inclination to the horizontal and with at least one outlet opening at its lowermost point, a horizontal base plate disposed immediately above the said first base plate, and forming the support base for the fill material, and which is in the form of a screen base, two different lid formations extending in a gas-tight manner over the clear width of the container and being vertically adjustable along the inner wall, and a travelling undercarriage receiving the entire container.

Abstract: A room partition is made of wall elements, which can be moved and be brought in tight contact, with their vertical front sides, with each other, and with locking elements. The wall elements are movable with the aid of suspension assemblies along a first track (10) and at least along a second track (4), whereby the first track (10) branches from the second track (4), and whereby with the first track (10), along which it can move, is associated a conveying mechanism (12) to which are attached catches (30) that, for the transportation of a wall element along the first track (10) can be brought in detachable engagement with its suspension assemblies. For transition of a wall element between the first and the second track (10,4), each catch (30) can be swung toward or away from a suspension assembly (6) of the wall element present in the branch point (34), in order to be engaged with or detached from this suspension assembly.

Abstract: Given is a formed partition made of displaceable wall elements that are suspended, by means of carrier studs, on two carrier members that are displaceable in guide rails, and movable along their perpendicular interfaces in sealing contact against one another and/or against terminal elements. Situated on the horizontal interfaces of the wall elements are sealing strips that are capable of being extended in contact against the floor and/or the guide rails or the ceiling of the room. On one of the wall elements, one of the carrier studs is journaled in horizontally-displaceable fashion toward the other carrier stud. In order to be able to execute a simple and rapid transport of the wall elements, even diagonally, running in the guide rail is a drivable endless element to which are fixed, at a predetermined interval apart, two followers.

Abstract: Wood preservatives contain a mixture of 2-iodobenzanilide with a quaternary ammonium compound.

Abstract: A method and apparatus for producing a directed aerosol stream from gaseous and/or vapor phase reactants by conveying the reactants to a reaction site, reacting the reactants at the reaction site in a flame free chemical reaction to produce an aerosol composition, and causing the aerosol composition to flow from the reaction site and immediately surrounding the aerosol composition with a moving, essentially aerosol free gas and/or vapor stream to form a directed aerosol stream enveloped in the aerosol free stream, in which the step of conveying includes conducting each reactant through a respective distributor and then through a discharge element having a substantially higher flow resistance than the distributor in a substantially vertical upward direction to the reaction site, and the step of causing is carried out so that the aerosol composition flows in a substantially vertical upward direction.

Abstract: A work tool for the separation of tubes, wherein two deforming rollers rigidly mounted on the tool are moveably arranged tangential to the tube for separating the tube up to a remaining section by deformation without cutting. Thereafter the full separation is effected by a cutting roller movable radially toward the tube and advanced thereto by the work tool.

Abstract: A vertically movable welding and/or cutting torch is automatically disconnected from its drive when the torch bumps into a work piece.

Abstract: The invention relates to a method of producing on a transparent article, particularly a glass article, layers having a reflection degree of at least 10 percent on a first surface of the article and dereflecting layers on a second surface of the article. The method includes the steps of first by an immersion process providing both said surfaces with a dereflecting multiple-layered coating, and then providing said first surface with a single layer of a reflection increasing transparent coating.

Abstract: A four-way pallet is of rectangular shape and is unitarily formed inwardly f each of its longitudinal edges with a row of three edge bosses projecting and tapering from one of the faces of the pallet. These bosses constitute feet for the pallet and define a pair of parallel ways across the plate at the one face and perpendicular to the longitudinal edges of the pallet. The plate is further formed between and parallel to the edge rows with a row of two middle bosses projecting and tapering from the one pallet face and each formed with apertures in line with the ways. Thus tines of a lift fork can pass under the pallet standing on the bosses between the edge bosses and through the apertures of the middle bosses. Such an arrangement of staggered bosses on the pallet provides continuous support therefor when rolling on a roller-type conveyor in a direction parallel to the longitudinal edges. The pallet is of uniform thickness throughout and the feet have flat faces and sides formed as isosceles trapezoids.