Patents by Inventor Werner Leupin

Werner Leupin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5824698
    Abstract: Novel and known dibenzimidazoles of the formula ##STR1## wherein R.sup.1 and R.sup.2 can be the same or different and signify C.sub.6 H.sub.4 R.sup.3 --, C.sub.6 H.sub.3 (OH)R.sup.4 -- or heterocyclyl,R.sup.3 signifies hydroxy, amino, lower alkoxy or cyano andR.sup.4 signifies halogen, lower alkyl or lower alkoxy,as well as pharmaceutically usable salts of compounds of general formula I are antibacterials, especially against Staphylococcus, Enterococcus and Heliobacter pylori.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: October 20, 1998
    Assignee: Hoffman-La Roche Inc.
    Inventors: Walter Hasler, Yu-Hua Ji, Werner Leupin
  • Patent number: 5736557
    Abstract: Disclosed are N,N'-bis(quinolin-4-yl)diamine derivatives of general formula I wherein R.sup.1 signifies halogen or trifluoromethyl, R.sup.2 signifies hydrogen or halogen, A signifies cyclohexane-1,3-diyl, 2-methyl-cyclohexane-1,3-diyl, cyclohexane-1,4-diyl, dicyclohexylmethane-4,4'-diyl, cyclopentane-1,3-diyl, phenylene-1,4, phenylene-1,3 and phenylene-1,2; n is 1 or 2; m is 1 or 2, as well as their pharmaceutically acceptable salts. These products are useful as agents for preventing malaria and for treating it, especially where the pathogens are resistant to chloroquine.
    Type: Grant
    Filed: December 16, 1996
    Date of Patent: April 7, 1998
    Assignee: Hoffman-La Roche, Inc.
    Inventors: Werner Hofheinz, Werner Leupin