Patents by Inventor Werner Zaugg

Werner Zaugg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Picolinic acid derivatives and their use as intermediates
    Patent number: 10633341
    Abstract: The present invention relates to new picolinic acid derivatives of formula (I) and their use as intermediates in the process of making pyridine derivatives, including (S)-3-amino-6-methoxy-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)picolinamide that are useful for the treatment of respiratory disorders.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: April 28, 2020
    Inventors: Thomas Heinz, Benjamin Martin, Florian Andreas Rampf, Werner Zaugg
  • NEW PICOLINIC ACID DERIVATIVES AND THEIR USE AS INTERMEDIATES
    Publication number: 20190345107
    Abstract: The present invention relates to new picolinic acid derivatives of formula (I) and their use as intermediates in the process of making pyridine derivatives, including (S)-3-amino-6-methoxy-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)picolinamide that are useful for the treatment of respiratory disorders.
    Type: Application
    Filed: December 18, 2017
    Publication date: November 14, 2019
    Inventors: Thomas HEINZ, Benjamin MARTIN, Florian Andreas RAMPF, Werner ZAUGG
  • PROCESS FOR THE MANUFACTURE OF ORGANIC COMPOUNDS
    Publication number: 20090299065
    Abstract: A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.
    Type: Application
    Filed: July 2, 2009
    Publication date: December 3, 2009
    Inventors: Guang-Pei Chen, Prasad Koteswara Kapa, Eric M. Loeser, Ulrich Beutler, Werner Zaugg, Michael John Girgis
  • Process for the manufacture of organic compounds
    Patent number: 7572917
    Abstract: A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: August 11, 2009
    Assignee: Novartis AG
    Inventors: Guang-Pei Chen, Prasad K Kapa, Eric M Loeser, Ulrich Beutler, Werner Zaugg, Michael J Girgis
  • Dibenzo [b,f]azepine intermediates
    Patent number: 7112673
    Abstract: The invention relates to new processes for the preparation of the pharmaceutical oxcarbazepine, as well as novel intermediates prepared by or used for said processes, and the preparation of said intermediates.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: September 26, 2006
    Assignee: Novartis AG
    Inventors: Peter Funfschilling, Daniel Kaufmann, Olivier Lohse, Ulrich Beutler, Werner Zaugg
  • Process for the manufacture of organic compounds
    Patent number: 6835838
    Abstract: A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: December 28, 2004
    Assignee: Novartis AG
    Inventors: Guang-Pei Chen, Prasad Koteswara Kapa, Eric M. Loeser, Ulrich Beutler, Werner Zaugg, Michael John Girgis
  • Process for the manufacture of organic compounds
    Publication number: 20040249154
    Abstract: A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.
    Type: Application
    Filed: July 14, 2004
    Publication date: December 9, 2004
    Inventors: Guang-Pei Chen, Prasad Koteswara Kapa, Eric M. Loeser, Ulrich Beutler, Werner Zaugg, Michael J. Girgis
  • Process for the manufacture of organic compounds
    Publication number: 20030208072
    Abstract: A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.
    Type: Application
    Filed: January 24, 2003
    Publication date: November 6, 2003
    Inventors: Guang-Pei Chen, Prasad Koteswara Kapa, Eric M. Loeser, Ulrich Beutler, Werner Zaugg, Michael John Girgis
  • Dibenzo(b,f)azepine derivatives and their preparation
    Publication number: 20030032800
    Abstract: The invention relates to new processes for the preparation of the pharmaceutical oxcarbazepine, as well as novel intermediates prepared by or used for said processes, and the preparation of said intermediates.
    Type: Application
    Filed: August 2, 2002
    Publication date: February 13, 2003
    Inventors: Peter Fnfschilling, Daniel Kaufmann, Olivier Lohse, Ulrich Beutler, Werner Zaugg
  • Rotary snow plow
    Patent number: 6367176
    Abstract: The rotary snow blower plow with a plow worm (18) which delivers the snow and a fan blower (19) which throws the delivered snow. The fan blower (19) is located on a line with the plow worm (18). The fan blower (19) and the plow worm (18) can be mounted on a common shaft (23) so that they rotate with the same angular speed. The rotary snow blower plow is characterized by high efficiency since the flow of snow need not be deflected by 90 degrees. It is especially suited for clearing of side walls and preparation of half pipe courses.
    Type: Grant
    Filed: October 15, 1999
    Date of Patent: April 9, 2002
    Assignee: Zaugg AG Eggiwil
    Inventors: Werner Zaugg, Klaus Maurer