Patents by Inventor Wesley B. Dong

Wesley B. Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11162910
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: November 2, 2021
    Assignees: CALIPER LIFE SCIENCES, INC., Canon U.S.A., Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Edward Donlon, Robert Moti, Michael Slater
  • Patent number: 10871460
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: December 22, 2020
    Assignee: Canon U.S.A., Inc.
    Inventors: Ivor T. Knight, Deborah John Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Allen Boronkay, Edward Donlon, Robert Moti, Michael Slater, Steven A. Sundberg, Michael R. Knapp
  • Patent number: 10500585
    Abstract: The present invention provides methods, systems, assemblies, and articles for extracting restrained liquid (e.g., surface tension-restrained liquid) from open wells in a chip, where the restrained liquid does not flow out of the wells due to gravity when the wells are held upside down. For example, the present invention provides extraction fixtures that may be attached to, and/or held adjacent to, a chip such that any restrained liquid that is forced out of the open wells is collected by, or flows through, the extraction fixtures. Also for example, the present invention provides assemblies composed of a extraction fixture attached to, and/or held adjacent to, a chip, and methods of subjecting such assemblies to a force such that at least a portion of the restrained liquid in the open wells is forced out and collected by, or flows through, the extraction fixture.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: December 10, 2019
    Assignee: TAKARA BIO USA, INC.
    Inventors: Bradley L. Griswold, Syed A. Husain, Robert Moti, Wesley B. Dong, GoPaul Kotturi, Jude Dunne, Philip Lin
  • Publication number: 20180321170
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Application
    Filed: May 25, 2018
    Publication date: November 8, 2018
    Applicants: Canon U.S. Life Sciences, Inc., CALIPER LIFE SCIENCES, INC.
    Inventors: Ivor T. Knight, Deborah John Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Allen Boronkay, Edward Donlon, Robert Moti, Michael Slater, Steven A. Sundberg, Michael R. Knapp
  • Patent number: 9983155
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 29, 2018
    Assignees: Canon U.S. Life Sciences, Inc., CALIPER LIFE SCIENCES, INC.
    Inventors: Ivor T. Knight, Deborah John Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Allen Boronkay, Edward Donlon, Robert Moti, Michael Slater, Steven A. Sundberg, Michael R. Knapp
  • Publication number: 20170001193
    Abstract: The present invention provides methods, systems, assemblies, and articles for extracting restrained liquid (e.g., surface tension-restrained liquid) from open wells in a chip, where the restrained liquid does not flow out of the wells due to gravity when the wells are held upside down. For example, the present invention provides extraction fixtures that may be attached to, and/or held adjacent to, a chip such that any restrained liquid that is forced out of the open wells is collected by, or flows through, the extraction fixtures. Also for example, the present invention provides assemblies composed of a extraction fixture attached to, and/or held adjacent to, a chip, and methods of subjecting such assemblies to a force such that at least a portion of the restrained liquid in the open wells is forced out and collected by, or flows through, the extraction fixture.
    Type: Application
    Filed: September 19, 2016
    Publication date: January 5, 2017
    Inventors: Bradley L. Griswold, Syed A. Husain, Robert Moti, Wesley B. Dong, GoPaul Kotturi, Jude Dunne, Philip Lin
  • Publication number: 20160377562
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Application
    Filed: June 27, 2016
    Publication date: December 29, 2016
    Applicants: CALIPER LIFE SCIENCES, INC., CANON U.S. LIFE SCIENCES, INC.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Allen Boronkay, Edwawrd Donlon, Robert Moti, Michael Slater
  • Patent number: 9447925
    Abstract: The present invention provides methods, systems, assemblies, and articles for extracting restrained liquid (e.g., surface tension-restrained liquid) from open wells in a chip, where the restrained liquid does not flow out of the wells due to gravity when the wells are held upside down. For example, the present invention provides extraction fixtures that may be attached to, and/or held adjacent to, a chip such that any restrained liquid that is forced out of the open wells is collected by, or flows through, the extraction fixtures. Also for example, the present invention provides assemblies composed of a extraction fixture attached to, and/or held adjacent to, a chip, and methods of subjecting such assemblies to a force such that at least a portion of the restrained liquid in the open wells is forced out and collected by, or flows through, the extraction fixture.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: September 20, 2016
    Assignee: WAFERGEN, INC.
    Inventors: Bradley L. Griswold, Syed A. Husain, Robert Moti, Wesley B. Dong, GoPaul Kotturi, Jude Dunne, Philip Lin
  • Patent number: 9376718
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: June 28, 2016
    Assignees: Caliper Life Sciences, Inc., Canon U.S. Life Sciences, Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron J. Rulison, Wesley B. Dong, Edward P. Donlon, Robert J. Moti, Andrew G. Fabans, Allen R. Boronkay, Michael Slater
  • Patent number: 8900811
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: February 9, 2006
    Date of Patent: December 2, 2014
    Assignees: Caliper Life Sciences, Inc., Canon U.S. Life Sciences, Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron J. Rulison, Wesley B. Dong, Andrew G. Fabans, Allen R. Boronkay, Edward P. Donlon, Robert J. Moti, Michael Slater
  • Publication number: 20140130885
    Abstract: The present invention provides methods, systems, assemblies, and articles for extracting restrained liquid (e.g., surface tension-restrained liquid) from open wells in a chip, where the restrained liquid does not flow out of the wells due to gravity when the wells are held upside down. For example, the present invention provides extraction fixtures that may be attached to, and/or held adjacent to, a chip such that any restrained liquid that is forced out of the open wells is collected by, or flows through, the extraction fixtures. Also for example, the present invention provides assemblies composed of a extraction fixture attached to, and/or held adjacent to, a chip, and methods of subjecting such assemblies to a force such that at least a portion of the restrained liquid in the open wells is forced out and collected by, or flows through, the extraction fixture.
    Type: Application
    Filed: November 8, 2013
    Publication date: May 15, 2014
    Applicant: WAFERGEN, INC.
    Inventors: Bradley L. Griswold, Syed A. Husain, Robert Moti, Wesley B. Dong, GoPaul Kotturi, Jude Dunne, Philip Lin
  • Publication number: 20140093879
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 3, 2014
    Applicant: Canon U.S. Life Sciences, Inc.
    Inventors: Ivor T. Knight, Deborah John Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Allen Boronkay, Edward Donlon, Robert Moti, Michael Slater
  • Publication number: 20120288865
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Application
    Filed: April 11, 2012
    Publication date: November 15, 2012
    Applicants: Canon U.S. Life Sciences, Inc., Caliper Life Sciences, Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron J. Rulison, Wesley B. Dong, Edward P. Donlon, Robert J. Moti, Andrew G. Fabans, Allen R. Boronkay, Michael Slater
  • Patent number: 6441305
    Abstract: A seal kit for assembly into a system for sealing an elongate heating cable from ambient essentially includes a cone-shaped elastomeric grommet, several molded plastic parts, and a compression spring. The compression grommet forms a sealing interface between itself and a molded plastic enclosure body and between itself and an outer jacket of a heating cable. Cable ends are sealed within a sealed interior space of the enclosure body. A cup-shaped surface of a molded plastic part adjacently facing a congruent cone-shaped surface of the elastomeric grommet forms a slip-plane. The compression spring transfers energy to compress the elastomeric grommet and to cause it to expand radially against an interior wall of the enclosure body and against an outer jacket of the electrical cable and prevents that region of the grommet from becoming bonded over a high temperature operating interval to the inside wall of the enclosure body.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 27, 2002
    Assignee: Tyco Electronics Corporation
    Inventor: Wesley B. Dong
  • Patent number: 5792987
    Abstract: An apparatus for sealing the end of an elongate cable such as a heating cable includes (1) a housing with a first open end and a second open end and a strain relief element positioned within the housing, (2) a flexible container which can be positioned over the cable end and (i) is of generally tubular shape, (ii) has an interior surface and an exterior surface, (iii) has a first open end and a second closed end, and (iv) contains a sealant; and (3) a cap which can be mated with the housing at the second open end, and cover the flexible container. The apparatus has excellent moisture-resistant properties even after repeated exposure to high temperatures, is reenterable, and can be readily mounted on a substrate such as a pipe.
    Type: Grant
    Filed: August 28, 1995
    Date of Patent: August 11, 1998
    Assignee: Raychem Corporation
    Inventors: Wesley B. Dong, Helen D. Shaughnessy, Jeffrey T. Haller, Daniel T. Emerson, Jae Yoon Jung, Larry M. Edwards
  • Patent number: 5767448
    Abstract: An apparatus for sealing a core of an elongate cable in which a polymeric core of an insulating or a conductive polymer is positioned between first and second elongate electrodes. The apparatus is a container which has a first portion with an open end into which the cable can be inserted and a second partially closed end which has first and second openings. The first portion also contains a sealant, e.g. a grease or a gel. A first removable guide tube is inserted through the first opening and a second removable guide tube is inserted through the second opening, the first and second guide tubes being suitable for insertion of the first and second elongate electrodes, respectively. The apparatus allows insertion of the elongate electrodes after the polymer has been removed from them, without allowing contact between the electrodes and the sealant.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: June 16, 1998
    Assignee: Raychem Corporation
    Inventor: Wesley B. Dong