Patents by Inventor Wie-Jong Kwak

Wie-Jong Kwak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9326960
    Abstract: Disclosed is a composition for preventing or treating eye diseases. The composition for preventing or treating eye diseases contains S-allyl-L-cysteine, a pharmaceutically acceptable salt thereof, or a solvate or a hydrate thereof as an active ingredient, and may inhibit photo-oxidation. The composition for preventing or treating eye diseases inhibits the accumulation of A2E in retinal pigment epithelial cells and the oxidation of A2E, thereby remarkably preventing or treating eye diseases including age-related macular degeneration or degenerative retinal disorder.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: May 3, 2016
    Assignee: PHARMAKING CO., LTD.
    Inventors: Soon Bae Kim, Gwang Soon Kim, Wan Bae Kim, Wie Jong Kwak, Sun Duck Jeon, Hyung Young Yoon, Young Pyo Jang
  • Patent number: 9180153
    Abstract: The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: November 10, 2015
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Chang-Kyun Han, Kiwon Joung, Hunseung Yoo, Yong-Baik Cho, Keun Ho Ryu, Hye Yeon Baek, Taek-Soo Kim, In Ho Jung, Wie-Jong Kwak
  • Publication number: 20150231100
    Abstract: Disclosed is a composition for preventing or treating eye diseases. The composition for preventing or treating eye diseases contains S-allyl-L-cysteine, a pharmaceutically acceptable salt thereof, or a solvate or a hydrate thereof as an active ingredient, and may inhibit photo-oxidation. The composition for preventing or treating eye diseases inhibits the accumulation of A2E in retinal pigment epithelial cells and the oxidation of A2E, thereby remarkably preventing or treating eye diseases including age-related macular degeneration or degenerative retinal disorder.
    Type: Application
    Filed: August 19, 2013
    Publication date: August 20, 2015
    Inventors: Soon Bae Kim, Gwang Soon Kim, Wan Bae Kim, Wie Jong Kwak, Sun Duck Jeon, Hyung Young Yoon, Young Pyo Jang
  • Publication number: 20150147411
    Abstract: The present invention relates to a composition for preventing or treating colitis. According to one embodiment of the present invention, the composition for preventing or treating colitis comprises S-allyl-L-cysteine, a pharmaceutically acceptable salt thereof, or a solvate or hydrate of the same as an active ingredient, and exhibits an anti-inflammatory action in colitis. The composition for preventing or treating colitis has outstanding effects in preventing and alleviating colitis due to the effect of the anti-inflammatory action and the effect of an antioxidant action of S-allyl-L-cysteine, while at the same time S-allyl-L-cysteine is not accompanied by side-effects, therefore, has a wide scope of use against colitis.
    Type: Application
    Filed: July 3, 2013
    Publication date: May 28, 2015
    Applicant: PHARMAKING CO., LTD.
    Inventors: Soon Bae Kim, Gwang Soon Kim, Wan Bae Kim, Wie Jong Kwak, Sun Duck Jeon, Hyung Young Yoon, Ki Baik Hahm, Eun Hee Kim
  • Patent number: 8790687
    Abstract: The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 29, 2014
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Wonrack Choi, Chang-Kyun Han, Tae Kon Kim, Guang-Jin Im, Chil Mann Jung, Se Jun Yun, Bongcheol Kim, Soomin Lee, Wie-Jong Kwak
  • Patent number: 8652537
    Abstract: The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: February 18, 2014
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Chang-Kyun Han, Wie-Jong Kwak, Ki Won Joung, Hun Seung Yoo, Do Seung Kum, Yong-Baik Cho, Keun Ho Ryu, Hae In Rhee, Taek Su Kim, In Ho Jung, So Yoon Lee, Jung Bum Yi, Joo Hyon Kim, Key An Um
  • Publication number: 20140024716
    Abstract: A composition including S-allyl-L-cysteine as an active ingredient and having an anti-Helicobacter pylori activity or a gastric mucosa protective effect, a composition for preventing, relieving, or treating gastrointestinal disorders, and a method of using the compositions.
    Type: Application
    Filed: July 26, 2013
    Publication date: January 23, 2014
    Applicant: PHARMAKING CO., LTD.
    Inventors: Soon Bae KIM, Gwang Soon KIM, Wan Bae KIM, Wie Jong KWAK, Sung Hye BANG
  • Publication number: 20120196936
    Abstract: A composition including S-allyl-L-cysteine as an active ingredient and having an anti-Helicobacter pylori activity or a gastric mucosa protective effect, a composition for preventing, relieving, or treating gastrointestinal disorders, and a method of using the compositions.
    Type: Application
    Filed: September 20, 2010
    Publication date: August 2, 2012
    Applicant: PHARMAKING CO., LTD.
    Inventors: Soon Bae Kim, Gwang Soon Kim, Wan Bae Kim, Wie Jong Kwak, Sung Hye Bang
  • Publication number: 20120148693
    Abstract: The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.
    Type: Application
    Filed: February 21, 2012
    Publication date: June 14, 2012
    Inventors: Chang-Kyun HAN, Wie-Jong KWAK, Ki Won JOUNG, Hun Seung YOO, Do Seung KUM, Yong-Baik CHO, Keun Ho RYU, Hae In RHEE, Taek Su KIM, In Ho JUNG, So Yoon LEE, Jung Bum YI, Joo Hyon KIM, Key An UM
  • Patent number: 8158168
    Abstract: The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer and momordica saponin I isolated therefrom. The Momordicae semen extract and the momordica saponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: April 17, 2012
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Bong Cheol Kim, Joo Hyon Kim, Se Jun Yun, Eun Jung Noh, Gi Uk Jang, Chang-Kyun Han, Yong-Baik Cho, Wie-Jong Kwak
  • Publication number: 20120021011
    Abstract: The present invention relates to a pharmaceutical composition for alleviating or treating inflammations and/or pains, the pharmaceutical composition comprising extracts from Broussonetia papyrifera and Lonicera japonica as an effective component. The present invention is based on a finding that when a prenylated flavonoid-enriched extract from Broussonetia papyrifera and an ethanol extract from Lonicera japonica are administered in combination, excellent and synergetic anti-inflammatory and analgesic effects are obtained in in vitro and in vivo tests, compared to when the extracts are separately administered.
    Type: Application
    Filed: December 7, 2010
    Publication date: January 26, 2012
    Inventors: Soon Bae Kim, Gwang Soon Kim, Wan Bae Kim, Wie Jong Kwak, Sung Hye Bang, Hyun Pyo Kim, Kun Ho Son
  • Patent number: 8048912
    Abstract: The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-? receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: November 1, 2011
    Assignees: SK Chemicals Co., Ltd., Korea Research Institute of Chemical Technology
    Inventors: Young-Dae Gong, Jin-Soo Seo, Moon-Kook Jeon, Wie-Jong Kwak, Yong-Baik Cho, Nam Kyu Lee, Eun Ju Lee, Jung Bum Lee, Jun Won Lee, Sukho Lee, Mi-Sook Dong, Jeong-Ran Kim
  • Patent number: 7919127
    Abstract: This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: April 5, 2011
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Wonrack Choi, Chang-Kyun Han, Jung-Woo Seo, Guang-Jin Im, ChilMann Jung, Se Jun Yun, Wie-Jong Kwak, Tae Kon Kim, bongcheol Kim, Soomin Lee
  • Publication number: 20100310687
    Abstract: The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer and momordica saponin I isolated therefrom. The Momordicae semen extract and the momordica saponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.
    Type: Application
    Filed: August 16, 2010
    Publication date: December 9, 2010
    Applicant: SK Chemicals Co., Ltd.
    Inventors: Bong Cheol KIM, Joo Hyon Kim, Se Jun Yun, Eun Jung Noh, Gi Uk Jang, Chang-Kyun Han, Yong-Baik Cho, Wie-Jong Kwak
  • Publication number: 20100221371
    Abstract: The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.
    Type: Application
    Filed: May 12, 2010
    Publication date: September 2, 2010
    Inventors: Chang-Kyun HAN, Kiwon Joung, Hunseung Yoo, Yong-Baik Cho, Keun Ho Ryu, Hye Yeon Baek, Taek-Soo Kim, In Ho Jung, Wie-Jong Kwak
  • Publication number: 20100190968
    Abstract: The present invention relates to the use of oleanane-type triterpene saponin compounds, which are effective for improving memory and learning ability, as an effective ingredient of drugs for the treatment and prevention of dementia and mild cognitive impairment and health foods for the improvement of brain functions including cognitive function.
    Type: Application
    Filed: October 24, 2006
    Publication date: July 29, 2010
    Inventors: Bong Cheol Kim, Wonrack Choi, Soo Min Lee, Se Jun Yun, Chang-Kyun Han, Guang-Jin Im, Wie-Jong Kwak
  • Publication number: 20100099763
    Abstract: The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
    Type: Application
    Filed: December 21, 2009
    Publication date: April 22, 2010
    Inventors: Wonrack CHOI, Chang-Kyun Han, Tae Kon Kim, Guang-Jin Im, Chil Mann Jung, Se Jun Yun, Bongcheol Kim, Soomin Lee, Wie-Jong Kwak
  • Patent number: 7695741
    Abstract: Disclosed is a topical formulation for preventing or treating acne, in particular to a topical formulation for preventing or treating acne through the antimicrobial activity of the formulation against acne-causing bacteria, Propionibacterium acnes, inhibition of excess production of sebum by inhibition of excess production of sebum by inhibition of 5?-reductase, inhibition of comedo, keratolysis and anti-inflammatory action, which comprises extract obtained from at least one oriental medicine selected from the group consisting of Cavalia gladiata, Biota orientalis and Coptis chinensis.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: April 13, 2010
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Soon Keun Lee, Wie-Jong Kwak, Chang-Kyun Han, Joo Hyon Kim
  • Publication number: 20090004309
    Abstract: The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer and momordica saponin I isolated therefrom. The Momordicae semen extract and the momordica saponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.
    Type: Application
    Filed: December 20, 2006
    Publication date: January 1, 2009
    Inventors: Bong Cheol Kim, Joo Hyon Kim, Se Jun Yun, Eun Jung Noh, Gi Uk Jang, Chang-Kyun Han, Yong-Baik Cho, Wie-Jong Kwak
  • Publication number: 20080248143
    Abstract: This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.
    Type: Application
    Filed: February 3, 2005
    Publication date: October 9, 2008
    Inventors: Wonrack Choi, Chang-Kyun Han, Jung-Woo Seo, Guang-Jin Im, Chilmann Jung, Se Jun Yun, Wie-Jong Kwak, Tae Kon Kim, Bongcheol Kim, Soomin Lee