Abstract: Methods and systems for monitoring, preventing and/or treating upper airway disorders such as apnea, dysphagia, reflux and/or snoring are described. The methods and systems monitor the upper airway disorders by processing one or more neural signals obtained from one or more upper airway afferents. Upper airway disorders are prevented and/or treated by delivering one or more stimulations to one or more reflex-related afferents, efferents, muscles, and sensory receptors to manipulate the threshold and/or trigger an upper airway reflex including, but not limited to a swallow reflex and/or a negative-pressure reflex.

Abstract: Methods and systems for monitoring, preventing and/or treating upper airway disorders such as apnea, dysphagia, reflux and/or snoring are described. The methods and systems monitor the upper airway disorders by processing one or more neural signals obtained from one or more upper airway afferents. Upper airway disorders are prevented and/or treated by delivering one or more stimulations to one or more reflex-related afferents, efferents, muscles, and sensory receptors to manipulate the threshold and/or trigger an upper airway reflex including, but not limited to a swallow reflex and/or a negative-pressure reflex.

Abstract: Methods and systems for monitoring, preventing and/or treating upper airway disorders such as apnea, dysphagia, reflux and/or snoring are described. The methods and systems monitor the upper airway disorders by processing one or more neural signals obtained from one or more upper airway afferents. Upper airway disorders are prevented and/or treated by delivering one or more stimulations to one or more reflex-related afferents, efferents, muscles, and sensory receptors to manipulate the threshold and/or trigger an upper airway reflex including, but not limited to a swallow reflex and/or a negative-pressure reflex.

Abstract: An electrode assembly is described, which allows close and robust contact with a biological structure such as a nerve while simultaneously preventing compressive injury to the biological structure. The electrode assembly includes a compliant cuff body and at least one reinforcing element in an aspect. The reinforced compliant cuff body may expand and contract to accommodate swelling of underlying biological structures, to accommodate movements of the biological structures associated with body movements, and to closely fit biological structures with irregular or non-uniform cross-sectional profiles. The electrode assembly further includes at least one electrode for sending and/or receiving electric impulse data to/from the biological structure such as a nerve.

Abstract: A method and device for treating sleep apnea and sleep hypopnea by monitoring respiratory-related activity from the internal branch of the superior laryngeal nerve, interpreting these internal signals to detect and classify apnea events, and stimulating nerves or muscles to elicit appropriate corrective responses to adverse respiratory events.

Abstract: The present disclosure provides systems and methods for treating apnea by controlled delivery of a swallow stimulus to a subject in which apnea is detected. In the systems and method, burst electrical or mechanical stimulation to one or more swallow-related nerves and/or muscles can be timed for delivery between the expiratory phase of the respiration cycle, following detection of an apneic event in the subject.

Abstract: The present disclosure provides systems and methods for treating apnea by controlled delivery of a swallow stimulus to a subject in which apnea is detected. In the systems and method, burst electrical or mechanical stimulation to one or more swallow-related nerves and/or muscles can be timed for delivery between the expiratory phase of the respiration cycle, following detection of an apneic event in the subject.

Abstract: A method and system for circumventing sudden unexpected death in epilepsy (SUDEP) by monitoring a plurality of indicators related to the likelihood of SUDEP, processing and monitoring these indicators for conditions predisposing to SUDEP, selecting a preconfigured treatment to treat the existing set of high-risk conditions, and delivering or triggering apnea and/or seizure treatment of a preventive or therapeutic nature to prevent SUDEP.

Abstract: A method and device for treating sleep apnea and sleep hypopnea by monitoring respiratory-related activity from the internal branch of the superior laryngeal nerve, interpreting these internal signals to detect and classify apnea events, and stimulating nerves or muscles to elicit appropriate corrective responses to adverse respiratory events.