Patents by Inventor Willem Blom
Willem Blom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230115025Abstract: The invention relates to floating drug delivery systems (FDDS) that provide solutions to the particular problems often encountered with floating drug delivery systems described in the art. On such generally recognized problem is the vulnerability of the systems, especially damage to the gas-filled compartment making it accessible to water so as to impair its buoyancy, ultimately resulting in insufficient gastric residence time. The invention, in an aspect, provides a self-repairing FDDS that maintains its floating capacity after damaging. The floating drug delivery systems of the invention, furthermore, allow for incorporation of high loads of active ingredients. The floating drug delivery systems can be designed in such a way that release of active ingredient from the system occurs entirely independent from the pH of the fluid surrounding the system.Type: ApplicationFiled: June 7, 2022Publication date: April 13, 2023Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Patent number: 10881614Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.Type: GrantFiled: September 28, 2017Date of Patent: January 5, 2021Assignee: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20180140553Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.Type: ApplicationFiled: September 28, 2017Publication date: May 24, 2018Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20180078503Abstract: The invention relates to floating drug delivery systems (FDDS) that provide solutions to the particular problems often encountered with floating drug delivery systems described in the art. On such generally recognized problem is the vulnerability of the systems, especially damage to the gas-filled compartment making it accessible to water so as to impair its buoyancy, ultimately resulting in insufficient gastric residence time. The invention, in an aspect, provides a self-repairing FDDS that maintains its floating capacity after damaging. The floating drug delivery systems of the invention, furthermore, allow for incorporation of high loads of active ingredients. The floating drug delivery systems can be designed in such a way that release of active ingredient from the system occurs entirely independent from the pH of the fluid surrounding the system.Type: ApplicationFiled: September 28, 2017Publication date: March 22, 2018Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20150202158Abstract: The invention relates to floating drug delivery systems(FDDS) that provide solutions to the particular problems often encountered with floating drug delivery systems described in the art. On such generally recognized problem is the vulnerability of the systems, especially damage to the gas-filled compartment making it accessible to water so as to impair its buoyancy, ultimately resulting in insufficient gastric residence time. The invention, in an aspect, provides a self-repairing FDDS that maintains its floating capacity after damaging. The floating drug delivery systems of the invention, furthermore,allow for incorporation of high loads of active ingredients. The floating drug delivery systems can be designed in such a way that release of active ingredient from the system occurs entirely independent from the pH of the fluid surrounding the system.Type: ApplicationFiled: July 15, 2013Publication date: July 23, 2015Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20140234409Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.Type: ApplicationFiled: July 16, 2012Publication date: August 21, 2014Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20100197855Abstract: The invention relates to a two-component curable polymer system comprising a first component including a water-curable silane-modified polymer and a second component comprising water as a curing agent wherein said second component is in the form of a paste or gel.Type: ApplicationFiled: June 13, 2008Publication date: August 5, 2010Applicant: INTERCON HOLLAND B.V.Inventor: Cornelis Willem Blom
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Patent number: 7025229Abstract: An assembly of a package that includes a flexible sheet-like foil material containing a viscous material, with apparatus for metered emptying of the package. The apparatus includes a frame, a guide, and a substantially flat two-part supporting surface. A metering control is movable along the supporting surface. The guide holds the metering control in a substantially fixed orientation relative to the supporting surface. The metering control empties the package by nipwise pressing the package flat onto the supporting surface. The frame includes a stationary part and a movable part, which parts form a continuous, uninterrupted supporting surface in a first position and which parts close off an open package by squeezing it shut in a second position.Type: GrantFiled: August 11, 2003Date of Patent: April 11, 2006Assignee: Intercon Holland B.V.Inventors: Victor Robert Bochno, Cornelis Willem Blom
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Publication number: 20040104248Abstract: An assembly provided with a package and an apparatus for the metered emptying of the package, which package contains viscous material and is at least partly manufactured from flexible sheet-like foil material. The apparatus comprises a frame with guide means and a substantially flat two-part supporting surface, as well as metering control means which, guided by the guiding means, can be moved, in a position substantially not changing as regards their orientation relative to the supporting surface, over and along the supporting surface. Emptying takes place by nipwise pressing the package flat onto the supporting surface with the metering control means.Type: ApplicationFiled: August 11, 2003Publication date: June 3, 2004Applicant: Intercon Holland B.V.Inventors: Victor Robert Bochno, Cornelis Willem Blom