Patents by Inventor William A. Riedl

William A. Riedl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermococcus barossii DNA polymerase mutants
    Patent number: 5882904
    Abstract: A Thermococcus barosii DNA polymerase with reduced 3'-5' exonuclease activity is disclosed. Additionally disclosed is a Thermococcus barosii DNA polymerase with increased ability to incorporate ribonucleotides and dideoxynucleotides.
    Type: Grant
    Filed: August 4, 1997
    Date of Patent: March 16, 1999
    Assignee: Amersham Pharmacia Biotech Inc.
    Inventors: William A. Riedl, Susan J. Fly, Barbara F. Kaboord, Steven H. Nye, Eve Y. Ting
  • In vitro phage lambda DNA packaging system
    Patent number: 5508187
    Abstract: A bacterial preparation capable of packaging phage .lambda. DNA is disclosed. This preparation is in lyophilized form and is stable at ambient temperature. In a preferred form, the preparation contains an over-expressed terminase protein, is prepared from the bacterial strain E. coli Cla [.lambda. c/857 Sam7 .DELTA.(cos-Nu1-A)::Kn.sup.r ]/.lambda. pTER and is capable of a packaging efficiency of at least 1.times.10.sup.8 pfu/.mu.g wild type .lambda. DNA. The present invention is also a method of creating a phage .lambda. DNA packaging extract comprising the steps of preparing a bacterial extract capable of packaging phage .lambda. and lyophilizing said extract.
    Type: Grant
    Filed: December 23, 1993
    Date of Patent: April 16, 1996
    Assignee: Pharmacia P-L Biochemicals, Inc.
    Inventors: Susan G. Frackman, Phillip P. Franciskovich, James F. Jolly, Robert A. Luhm, William A. Riedl