Patents by Inventor William A. Sklarz

William A. Sklarz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Riboflavin purification
    Patent number: 4165250
    Abstract: Riboflavin is recovered from fermentation broth by diluting the broth with a predetermined quantity of water, centrifuging the diluted broth to form a sludge, resuspending the sludge with a predetermined quantity of water, and centrifuging the resuspended sludge to yield a product usuable directly as an animal feed supplement or suitable for further purification for pharmaceutical use. Optionally the broth or resuspended sludge is treated with an enzyme before centrifugation.
    Type: Grant
    Filed: November 14, 1977
    Date of Patent: August 21, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Albert Epstein, Glen Graham, William A. Sklarz
  • Freeze-drying process for the preparation of meningococcus vaccine without degradation of potency
    Patent number: 4134214
    Abstract: The purified Group A polysaccharide antigen isolated from N. meningitidis for vaccination against this type of bacterial meningitidis is prepared from an isotonic ratio of aqueous sodium chloride solution freeze-dried at temperatures of from -20.degree. C. to -30.degree. C. This low temperature lyophilization dries the sodium chloride polysaccharide menstrum without loss of molecular weight, i.e., potency.
    Type: Grant
    Filed: August 5, 1977
    Date of Patent: January 16, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Glen D. Graham, William A. Sklarz
  • Process for the preparation of 4-methylthiazole
    Patent number: 4111948
    Abstract: Process for desulfurization of thiazoles including the removal of the mercapto group from 2-mercaptothiazoles and 2-mercaptobenzothiazoles and their derivatives by the oxidation with oxygen in the presence of an oxidation catalyst.
    Type: Grant
    Filed: November 26, 1976
    Date of Patent: September 5, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Henry S. Kao, William A. Sklarz, Leonard M. Weinstock