Abstract: A shaped cutter is disclosed for use on a drill bit. In one or more example, the shaped cutter includes a substrate including a proximal end and a distal end and defining a cutter axis extending between the proximal and distal ends. A cutting table secured to the proximal end of the substrate includes a cutting face with a central boss axially extending from the cutting face and a plurality of ribs radially extending across the cutting face from the boss to a periphery of the cutting table. The cutting face may recede axially from the periphery towards the central boss, such as by defining a planar section, a plurality of intersecting planar sections, and/or a concave (e.g., frustoconical) shape between adjacent ribs.

Abstract: A shingle includes a substrate having an asphalt coating on a top surface of the substrate and on a bottom surface of the substrate. A surface layer of granules is embedded in the asphalt on the top surface of the substrate. A backdust layer of particles is embedded in the asphalt on the bottom surface of the substrate. A sealant is disposed on the backdust. A hydrophobic material is applied to the sealant.

Abstract: A wetted-wire liquid-gas contactor device is disclosed comprising a plurality of wires, a first support structure configured to retain the plurality of wires, and a liquid distribution system for receiving and distributing a liquid to the plurality of wires. The diameter of the plurality of wires is approximately 2 mm or less, wherein a pitch of the plurality of wires is less than 4.0 mm.

Abstract: A battery comprising a lithium metal anode; a solid electrolyte; a cathode; and at least one interface layer between a surface of the cathode and a surface of the solid electrolyte, the interface layer formed of a printable lithium composition comprised of lithium metal powder, a polymer binder compatible with the lithium metal powder, a rheology modifier compatible with the lithium metal powder, and a solvent compatible with the lithium metal powder and with the polymer binder, wherein the interface layer improves the uniformity of the surface of the solid electrolyte thereby optimizing contact between the surface of the cathode and the surface of the solid electrolyte for better battery performance.

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.

Abstract: A superconductor device includes a high superconductivity transition temperature enhanced from the raw material transition temperature. The superconductor device includes a matrix material and a core material. The enhancing matrix material and the core material together create a system of strongly coupled carriers. A plurality of low-dimensional conductive features can be embedded in the matrix. The low-dimensional conductive features (e.g., nanowires or nanoparticles) can be conductors or superconductors. An interaction between electrons of the low-dimensional conductive features and the enhancing matrix material can promote excitations that increase a superconductivity transition temperature of the superconductor device.

Abstract: A structural mount is used for attaching devices to a gutter. The mount includes a gutter engaging portion and a device engaging portion. The gutter engaging portion including two gutter mounts. The gutter mounts include a spiral hook and a stabilizer. The spiral hook extends above a gutter lip and into a gutter channel such that a proximal point of the spiral hook is positioned against an inner surface of a front wall of the gutter, and the stabilizer contacts an outer surface of the front wall of the gutter when the attachment device is engaged with the gutter. The device engaging portion includes a mounting surface and a mounting plate. The mounting plate is capable of receiving a securing clip attached to a device such that the device may engage with the mounting surface via the mounting plate and the securing clip.

Abstract: A communication system includes a server and a client that transmits messages to the server. The messages include data and descriptive tags and may be in XML format. The server initiates a negotiation with the client relating to message format switching. If the client indicates that the client can accept message format switching, the server instructs the client to switch further messages to a simpler message format including solely data.

Abstract: Devices and methods for mixing and preparing therapeutic pellets are described. In one aspect, the present disclosure may include a medical device for mixing and preparing pharmaceuticals. The medical device may include a body sized and shaped to be supported by a human hand. The body may be elastically flexible between a relaxed shape and a flexed shape. In the relaxed shape, the body may form a basin and may be shaped and sized to receive a vessel for mixing or forming the therapeutic pellets. In the flexed shape, the bowl may be configured for controlled pouring of the therapeutic pellets.

Abstract: Energy is transmitted to a body lumen or passageway in the form of pulsed electric fields (PEFs) and in a manner which provides focal therapy. In some embodiments, PEFs are delivered through independent electrically active electrodes of an energy delivery body, typically in a monopolar fashion. Such delivery concentrates the electrical energy over a smaller surface area, resulting in stronger effects than delivery through an electrode extending circumferentially around the lumen or passageway. It also forces the electrical energy to be delivered in a staged regional approach, mitigating the effect of preferential current pathways through the surrounding tissue. Focal delivery of PEFs can provide increased tissue lethality by employing precise timing and sequencing of energy delivery to the electrodes.

Abstract: A push notification mechanism at a mobile user device provides for automated limiting of the rate of production of push notification alerts (such as an audible alert or a vibratory alert) and/or push notifications responsive to the occurrence of chat events relevant to a chat application hosted by the user device. Some chat events automatically trigger suppression periods during which push notification alerts are prevented for subsequent chat events that satisfy predefined suppression criteria. Such push notification and/or alert limiting can be performed separately for separate users, chat groups, and/or chat event types.

Abstract: A shingle includes a substrate having an asphalt coating on a top surface of the substrate and on a bottom surface of the substrate. A surface layer of granules is embedded in the asphalt on the top surface of the substrate. A backdust layer of particles is embedded in the asphalt on the bottom surface of the substrate. A sealant is disposed on the backdust. A hydrophobic material is applied to the sealant.

Abstract: A drill bit has a plurality of cutters secured to the bit body, including a gauge cutter defining a gauge diameter of the drill bit. A reciprocating gauge assembly on the bit comprises a cavity defined in the bit body, a piston reciprocably disposed in the cavity, a wear element on an outwardly facing end of the piston, a piston retainer for moveably retaining the piston in the cavity, and a spring biasing the piston outwardly to a neutral position of the wear element with respect to the gauge diameter. The wear element and piston may be urged inwardly in response to an applied load at the drill bit gauge pad, increasing the lateral depth of cut and thereby controlling the aggressiveness of the bit in response to the load.

Abstract: A tool interchange for a submersible remote operated vehicle (ROV) arm includes a first interchange body that affixes to an ROV arm. A second interchange body is carried by the first interchange body to rotate on a rotation axis. The second interchange body includes a tool mount actuable between gripping an ROV tool to the second interchange body and releasing the ROV tool from the second interchange body. An inductive power coupling part is provided in the tool mount. The inductive power coupling part is presented outwardly in the tool mount opposite the first interchange body, resides on the rotation axis and is fixed with respect to the first interchange body while the second interchange body rotates. The inductive power coupling part is adapted to inductively communicate power with a corresponding inductor power coupling part of the ROV tool when the ROV tool is docked in the tool mount.

Abstract: Systems and methods for adaptively tuning a Proportional, Integral and Derivative (PID) controller in a zero order industrial process are provided. A method and system can involve receiving input data at one or more inputs of the PID controller and generating output data at one or more outputs of the PID controller in response to processing the input data. Error(s) associated with the controller are determined based on an analysis of a measured parameter with respect to a desired setpoint. The measured parameter may be indicated in the output data. Adaptive gain may be applied to the PID controller in response to the absolute value of the controller error both exceeding a deadband and increasing. Additionally, normal gain, which is lower than the adaptive gain, may be applied to the PID controller in response to the absolute value of the controller error either being below the deadband or decreasing.

Abstract: A composite structural board having a structural board and a water-resistant barrier (WRB) sheet, and a wall system comprising same, wherein a face of the structural board is discontinuously attached to the inner face of the WRB sheet solely by a first adhesive, the WRB sheet fully covering the face of the structural board; wherein the unattached areas between the face of the structural board and the inner face of the WRB sheet define paths by which a liquid can move between the face of the structural board and the inner face of the WRB sheet; in some instances the WRB sheet material extends beyond at least one edge of the structural board forming a WRB sheet flap.

Abstract: Various embodiments can implement a multi-system or node architecture that can be deployed on-demand and augment existing systems with pre-configured nodes that can be installed within existing architecture. The multi-node architecture is flexible for integration into many systems and can also stand alone to provide data validation and assurance. Various embodiments of the multi-node architecture enable private and public distributed ledgers (e.g., blockchains) that enhance security, enhance confidentiality, and eliminate the need to trust the provider/hosts of the data validation information and/or the hosts of the confidential information.

Abstract: A composite structural board having a structural board and a water-resistant barrier (WRB) sheet, and a wall system comprising same, wherein a face of the structural board is discontinuously attached to the inner face of the WRB sheet solely by a first adhesive, the WRB sheet fully covering the face of the structural board; wherein the unattached areas between the face of the structural board and the inner face of the WRB sheet define paths by which a liquid can move between the face of the structural board and the inner face of the WRB sheet; in some instances the WRB sheet material extends beyond at least one edge of the structural board forming a WRB sheet flap.

Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the compound of Formula I, or pharmaceutically acceptable salt thereof is administered orally with a total dose of the compound of 0.1 mg/day to 5 mg/day, useful for treating a neurodegenerative disease, including neurodegenerative tauopathies, such as Alzheimer's disease, frontotemporal dementia, corticobasilar syndrome, and progressive supranuclear palsy.

Abstract: A system for providing hydrotherapy includes an attachment coupling structure that is configured to be secured to a bottom end portion of a socket that is configured to receive a residual limb of a subject. A fluid resistance attachment is coupled to the attachment coupling structure. The attachment coupling structure is configured to retain the fluid resistance attachment in a plurality of positions relative to the socket. The plurality of positions are rotationally offset relative to each other about an axis.