Patents by Inventor William Brinigar

William Brinigar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blood substitutes
    Publication number: 20050227912
    Abstract: The functional characteristics of heme proteins can be modified to produce hemoglobins that can be used as blood substitutes in different therapeutic applications. Stable polymers of tetrameric hemoglobin, and of myoglobin molecules, are provided for use in the blood substitutes.
    Type: Application
    Filed: November 1, 2004
    Publication date: October 13, 2005
    Inventors: Clara Fronticelli, William Brinigar
  • Modified human hemoglobin, blood substitutes containing the same, and vectors for expressing the modified hemoglobin
    Patent number: 5239061
    Abstract: The present invention relates to modified .beta.-chains of human hemoglobin having an oxygen binding affinity equal to or less than natural human hemoglobin. The modified the .beta.-chain of human hemoglobin of the invention preferably has at least one chloride binding site not present in .beta.-chain of natural human hemoglobin.
    Type: Grant
    Filed: June 20, 1990
    Date of Patent: August 24, 1993
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Clara Fronticelli, Enrico Bucci, William Brinigar