Patents by Inventor William Brunken

William Brunken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ? netrin and uses thereof
    Patent number: 7531625
    Abstract: ?-netrin nucleic acid molecules and polypeptides are provided. Methods of using the ?-netrin nucleic acid molecules and polypeptides are also provided.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: May 12, 2009
    Assignee: The General Hospital Corporation
    Inventors: Pamela Olson, Dale Hunter, William Brunken, Manuel Koch, Robert Burgeson
  • ?-netrin and uses thereof
    Patent number: 7390634
    Abstract: ?-netrin nucleic acid molecules and polypeptides are provided. Methods of using the ?-netrin nucleic acid molecules and polypeptides are also provided.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: June 24, 2008
    Assignees: The General Hospital Corporation, Tufts University
    Inventors: Pamela Olson, Dale Hunter, William Brunken, Manuel Koch, Robert Burgeson
  • Collagen XXII, a novel human collagen and uses thereof
    Publication number: 20070166736
    Abstract: The invention provides isolated nucleic acids molecules, designated collagen XXII nucleic acid molecules, which encode a novel collagen. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing collagen XXII nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a collagen XXII gene has been introduced or disrupted. The invention still further provides isolated collagen XXII proteins, fusion proteins, antigenic peptides and anti-collagen XXII antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: October 20, 2006
    Publication date: July 19, 2007
    Inventors: Robert Burgeson, Manuel Koch, Douglas Keene, William Brunken, Leena Bruckner-Tuderman
  • Beta netrin and uses thereof
    Publication number: 20040248178
    Abstract: &bgr;-netrin nucleic acid molecules and polypeptides are provided. Methods of using the &bgr;-netrin nucleic acid molecules and polypeptides are also provided.
    Type: Application
    Filed: April 26, 2004
    Publication date: December 9, 2004
    Applicant: The General Hospital Corporation, a Massachusetts corporation
    Inventors: Pamela Olson, Dale Hunter, William Brunken, Manuel Koch, Robert Burgeson
  • Laminins and uses thereof
    Patent number: 6682911
    Abstract: The present invention is based on the discovery of a novel member of the laminin family, laminin 12. Accordingly, the present invention features a purified or isolated preparation or a recombinant preparation of laminin 12 which includes an &agr;2 subunit, &bgr;1 subunit and a &ggr;3 subunit.
    Type: Grant
    Filed: May 1, 2000
    Date of Patent: January 27, 2004
    Assignee: The General Hospital Corporation
    Inventors: Robert E. Burgeson, Marie-France Champliaud, Pamela Olson, Manuel Koch, William Brunken
  • Beta netrin and uses thereof
    Publication number: 20030207347
    Abstract: &bgr;-netrin nucleic acid molecules and polypeptides are provided. Methods of using the &bgr;-netrin nucleic acid molecules and polypeptides are also provided.
    Type: Application
    Filed: February 28, 2001
    Publication date: November 6, 2003
    Inventors: Pamela Olson, Dale Hunter, William Brunken, Manuel Koch, Robert Burgeson
  • Laminin 15
    Patent number: 6635616
    Abstract: The present invention features a novel member of the laminin family, i.e., laminin 15, the methods of making these molecules, and the methods of using these molecules in treating neural disorders, e.g., retinal disorders.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: October 21, 2003
    Assignee: The General Hospital Corporation
    Inventors: Robert Burgeson, William Brunken, Marie-France Champliaud, Dale Hunter
  • Laminin 15 and uses thereof
    Publication number: 20020142954
    Abstract: The present invention features a novel member of the laminin family, i.e., laminin 15, the methods of making these molecules, and the methods of using these molecules in treating neural disorders, e.g., retinal disorders.
    Type: Application
    Filed: April 30, 2001
    Publication date: October 3, 2002
    Inventors: Robert Burgeson, William Brunken, Marie-France Champliaud, Dale Hunter