Patents by Inventor William C. Lumma, Jr.

William C. Lumma, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof
    Patent number: 4544654
    Abstract: Novel substituted sulfonamidobenzamides are described as useful antiarrhythmic agents. Their use in the treatment of cardiac arrhythmias, especially re-entrant arrhythmias, via the prolongation of the action potential of cardiac tissue is provided. Pharmaceutical formulations containing such compounds are also disclosed.
    Type: Grant
    Filed: March 20, 1984
    Date of Patent: October 1, 1985
    Assignee: Schering A.G.
    Inventors: David D. Davey, William C. Lumma, Jr., Ronald A. Wohl
  • Substituted derivatives of amino alkane diols as gastric secretion inhibitors
    Patent number: 4411899
    Abstract: There are disclosed substituted derivatives of amino alkane diols and related compounds as well as processes for the preparation of such compounds. These compounds are useful for the suppression of gastric acid secretions in mammals and compositions for such uses are also disclosed.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: October 25, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Imidazodiazines
    Patent number: 4408047
    Abstract: Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: November 19, 1981
    Date of Patent: October 4, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Imidazoazines and imidazodiazines
    Patent number: 4330543
    Abstract: Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: March 28, 1980
    Date of Patent: May 18, 1982
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Novel imidazoazines and imidazodiazines
    Patent number: 4233301
    Abstract: Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: December 14, 1978
    Date of Patent: November 11, 1980
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Certain imidazo(1,2a)pyridine derivatives
    Patent number: 4166851
    Abstract: Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: September 4, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Piperazinylpyrazines
    Patent number: 4163849
    Abstract: Substituted piperazinylpyrazines and pharmaceutically acceptable salts thereof which have pharmacological activity as anorexigenic agents.
    Type: Grant
    Filed: March 17, 1978
    Date of Patent: August 7, 1979
    Assignee: Merck & Co., Inc.
    Inventors: William C. Lumma, Jr., Walfred S. Saari, Anthony G. Zacchei
  • 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
    Patent number: 4091098
    Abstract: 3-(1-Piperazinyl)-1,2,4-benzotriazines, N-oxides and pharmaceutically acceptable salts thereof have serotoninmimetic activity. They are prepared by treating 3-halo-1,2,4-benzotriazines or N-oxides thereof with piperazine.
    Type: Grant
    Filed: April 25, 1977
    Date of Patent: May 23, 1978
    Assignee: Merck & Co., Inc.
    Inventor: William C. Lumma, Jr.
  • 6-(1-Piperazinyl)quinoxaline
    Patent number: 4091101
    Abstract: 6-(1-Piperazinyl)quinoxaline and pharmaceutically acceptable salts thereof have serotoninmimetic activity. It is prepared by reducing the nitro group of 1-(3-amino-4-nitrophenyl)piperazine followed by treatment with glyoxal.
    Type: Grant
    Filed: June 15, 1977
    Date of Patent: May 23, 1978
    Assignee: Merck & Co., Inc.
    Inventors: William C. Lumma, Jr., Walfred S. Saari
  • 6-Chloro-2-(1-piperazinyl)pyrazine
    Patent number: 4082844
    Abstract: The compound 6-chloro-2-(1'-piperazinyl)pyrazine, its N-oxides and acid-addition salts are disclosed having pharmacological activity as anorexic agents.
    Type: Grant
    Filed: June 15, 1976
    Date of Patent: April 4, 1978
    Assignee: Merck & Co., Inc.
    Inventors: William C. Lumma, Jr., Walfred S. Saari
  • 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines
    Patent number: 4082845
    Abstract: 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines and pharmaceutically acceptable salts thereof have serotoninmimetic activity. They are prepared by treating 3-halo-pyrido[2,3-b]pyrazines with piperazine.
    Type: Grant
    Filed: April 25, 1977
    Date of Patent: April 4, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Walfred S. Saari, William C. Lumma, Jr.
  • Piperazinylpyrazines
    Patent number: 4081542
    Abstract: Compounds of the formula: ##STR1## and their N-oxides and acid-addition salts are disclosed having pharmacological activity as anorexic agents.
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: March 28, 1978
    Assignee: Merck & Co., Inc.
    Inventors: William C. Lumma, Jr., Walfred S. Saari
  • Piperazinylpyridines
    Patent number: 4078063
    Abstract: Compounds of the formula: ##STR1## and their N-oxides and acid-addition salts are disclosed having pharmacological activity as anorexic agents.
    Type: Grant
    Filed: September 24, 1976
    Date of Patent: March 7, 1978
    Assignee: Merck & Co., Inc.
    Inventors: William C. Lumma, Jr., Walfred S. Saari