Abstract: The invention features a method of treating polyester material to generate functional carboxylic acid and amine groups. These functional groups can be used as sites for covalent bond formation to attach chemical or biological moieties. This bifunctionalized polyester polymer can be used in any medical application in which biocompatible polymers are used.

Abstract: The present invention provides a method for making an infection-preventive fabric article which is suitable for a non-invasive or topical usage as a medical treatment fabric, or as a health care product, or as a protective appliance. The method of manufacture applies broadly to any and all non-woven and woven fabrics including any and all cloths, gauzes, and/or films comprised in whole or in part of fibrous matter matrices or of discrete fibers; and provides prophylactic and protective antimicrobial/anti-fungal articles for use in a wide range and variety of biomedical, environmental, and safety-hazard applications.

Abstract: Provided is a biocompatible device which has been coated or sealed with a polyether or polyether/carbonate based urethane polymer that contains functional groups (e.g. carboxylic acid groups) which are capable of serving as anchor sites for protein binding.

Abstract: The present invention is a broadly applicable methodology for making a bioactive titanium surface which would be clinically-acceptable and effective as either an anti-thrombin, thrombolytic or growth promoting surface coating, or any combination of these. The bioactive surface can be prepared using any material comprising titanium in whole or in part; is suitable for inclusion upon the exposed surfaces of surgically implantable prostheses comprising titanium; offers a means for avoiding systemic anticoagulation therapy to reduce thrombus formation and thromboembolism in the living subject receiving a surgically implanted prosthesis; and provides a means to induce cellular attachment and proliferation onto the titanium surface of the implant.

Abstract: The invention features a method of treating polyester material to generate functional carboxylic acid and amine groups. These functional groups can be used as sites for covalent bond formation to attach chemical or biological moieties. This bifunctionalized polyester polymer can be used in any medical application in which biocompatible polymers are used.

Abstract: The present invention provides a method for making an infection-resistant fabricated textile article which is suitable for any in-vivo usage either as a topical bandage, on an implantable configured construct, or as part of a prosthetic mechanical appliance. The method of manufacture applies broadly to any and all fabrics, cloths, gauzes, and/or films comprised in whole or in part of fibers; and provides an infection-resistant textile of valued use in a wide range and variety of medical applications.

Abstract: The present invention provides a method for making an infection-resistant fabricated textile article which is suitable for any in-vivo usage either as a topical bandage, on an implantable configured construct, or as part of a prosthetic mechanical appliance. The method of manufacture applies broadly to any and all fabrics, cloths, gauzes, and/or films comprised in whole or in part of fibers; and provides an infection-resistant textile of valued use in a wide range and variety of medical applications.

Abstract: Provided is a biocompatible device which has been coated or sealed with a polyether or polyether/carbonate based urethane polymer that contains functional groups (e.g. carboxylic acid groups) which are capable of serving as anchor sites for protein binding.

Abstract: The invention provides urethane polymers bonded to therapeutically active compounds, such as antibiotics. The invention also features methods of applying therapeutically active compounds to polyurethane polymers using textile dyeing. These polymers may be used in a variety of clinical applications.