Abstract: Multi-specific binding proteins that bind NKG2D receptor, CD 16, and FLT3 are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of autoimmune disease or cancer.

Abstract: A leak detection system of a heating, ventilating, and air conditioning (HVAC) system includes a sensor configured to detect a UV tracer in a monitored gas volume of the HVAC system. The leak detection system also includes a controller communicatively coupled to the sensor. The controller is configured to modify operation of the HVAC system in response to the sensor detecting the UV tracer in the monitored gas volume.

Abstract: The present disclosure relates to a heating, ventilating, and air conditioning (HVAC) system that includes a refrigerant circuit and a sensor configured to measure a refrigerant concentration external to the refrigeration circuit. The HVAC system also includes a controller that is communicatively coupled to the sensor and to an economizer. The controller is configured to control a flow of environmental air into the HVAC system. The controller is further configured to increase a ratio of the flow of environmental air relative to a flow of return air from a conditioned interior space of a building when the sensor measures the refrigerant concentration above a predetermined threshold concentration.

Abstract: A heating ventilation and air conditioning (HVAC) control system. The HVAC control system includes a sensor that detects a refrigerant released from an HVAC system and emits a signal indicative of the detection. The HVAC control system also includes a switch that blocks a flow of electricity to an enclosed space and a controller that receives the signal from the sensor and activates the switch to block the flow of electricity in response to detection of the refrigerant.

Abstract: A heating ventilation and air conditioning (HVAC) control system. The HVAC control system includes a sensor that detects a refrigerant released from an HVAC system and emits a signal indicative of the detection. The HVAC control system also includes a switch that blocks a flow of electricity to an enclosed space and a controller that receives the signal from the sensor and activates the switch to block the flow of electricity in response to detection of the refrigerant.

Abstract: The present disclosure relates to a refrigeration circuit that includes a controller communicatively coupled to a compressor, an expansion valve, and a sensor of the refrigeration circuit. The controller may activate the compressor and actuate the expansion valve such that the compressor is active while the expansion valve is closed. The controller may also measure a pressure of a refrigerant in the refrigeration circuit using the sensor while the compressor is active and the expansion valve is closed. Additionally, the controller may determine whether a refrigerant leak exists based on a maximum measurement time being reached or a time difference between a first time associated with the compressor being active while the expansion valve is closed and a second time associated with the measured pressure falling below a threshold value.

Abstract: leak detection system of a heating, ventilating, and air conditioning (HVAC) system includes a sensor configured to detect a UV tracer in a monitored gas volume of the HVAC system. The leak detection system also includes a controller communicatively coupled to the sensor. The controller is configured to modify operation of the HVAC system in response to the sensor detecting the UV tracer in the monitored gas volume.

Abstract: A leak detection system of a heating, ventilating, and air conditioning (HVAC) system includes a sensor configured to detect a UV tracer in a monitored gas volume of the HVAC system. The leak detection system also includes a controller communicatively coupled to the sensor. The controller is configured to modify operation of the HVAC system in response to the sensor detecting the UV tracer in the monitored gas volume.

Abstract: The present disclosure relates to a heating, ventilating, and air conditioning (HVAC) system that includes a refrigerant circuit and a sensor configured to measure a refrigerant concentration external to the refrigeration circuit. The HVAC system also includes a controller that is communicatively coupled to the sensor and to an economizer. The controller is configured to control a flow of environmental air into the HVAC system. The controller is further configured to increase a ratio of the flow of environmental air relative to a flow of return air from a conditioned interior space of a building when the sensor measures the refrigerant concentration above a predetermined threshold concentration.

Abstract: The present disclosure relates to a heating, ventilating, and air conditioning (HVAC) system that includes a refrigerant circuit and a sensor configured to measure a refrigerant concentration external to the refrigeration circuit. The HVAC system also includes a controller that is communicatively coupled to the sensor and to an economizer. The controller is configured to control a flow of environmental air into the HVAC system. The controller is further configured to increase a ratio of the flow of environmental air relative to a flow of return air from a conditioned interior space of a building when the sensor measures the refrigerant concentration above a predetermined threshold concentration.

Abstract: A refrigerant gas sensing system of a heating, ventilating, and air conditioning (HVAC) system, wherein the refrigerant gas sensing system is configured to collect a sample from a monitored gas volume, to introduce an ignition source to the sample, to detect an amount of combustion product in the sample after ignition, to determine an amount of leaked refrigerant in the monitored gas volume based on the measured amount of combustion product, and to indicate the amount of leaked refrigerant in the monitored gas volume.

Abstract: A heating ventilation and air conditioning (HVAC) control system. The HVAC control system includes a sensor that detects a refrigerant released from an HVAC system and emits a signal indicative of the detection. The HVAC control system also includes a switch that blocks a flow of electricity to an enclosed space and a controller that receives the signal from the sensor and activates the switch to block the flow of electricity in response to detection of the refrigerant.

Abstract: A heating ventilation and air conditioning (HVAC) control system. The HVAC control system includes a sensor that detects a refrigerant released from an HVAC system and emits a signal indicative of the detection. The HVAC control system also includes a switch that blocks a flow of electricity to an enclosed space and a controller that receives the signal from the sensor and activates the switch to block the flow of electricity in response to detection of the refrigerant.

Abstract: The present disclosure relates to a refrigeration circuit that includes a controller communicatively coupled to a compressor, an expansion valve, and a sensor of the refrigeration circuit. The controller may activate the compressor and actuate the expansion valve such that the compressor is active while the expansion valve is closed. The controller may also measure a pressure of a refrigerant in the refrigeration circuit using the sensor while the compressor is active and the expansion valve is closed. Additionally, the controller may determine whether a refrigerant leak exists based on a maximum measurement time being reached or a time difference between a first time associated with the compressor being active while the expansion valve is closed and a second time associated with the measured pressure falling below a threshold value.

Abstract: The present disclosure relates to a refrigeration circuit that includes a controller communicatively coupled to a compressor, an expansion valve, and a sensor of the refrigeration circuit. The controller may activate the compressor and actuate the expansion valve such that the compressor is active while the expansion valve is closed. The controller may also measure a pressure of a refrigerant in the refrigeration circuit using the sensor while the compressor is active and the expansion valve is closed. Additionally, the controller may determine whether a refrigerant leak exists based on a maximum measurement time being reached or a time difference between a first time associated with the compressor being active while the expansion valve is closed and a second time associated with the measured pressure falling below a threshold value.

Abstract: A refrigerant leak detection system for a heating, ventilation, and air conditioning (HVAC) system includes a vessel configured to receive an air sample. The refrigerant leak detection system includes a cooling device configured to cool the vessel and a liquid detection device configured to detect liquid in the vessel. The refrigerant leak detection system further includes an actuator configured to actuate a transfer mechanism to collect the air sample in the vessel.

Abstract: An evaporator (168) in a vapor compression system (14) (168) includes a shell (76), a first tube bundle (78); a hood (86); a distributor (80); a first supply line (142); a second supply line (144); a valve (122) positioned in the second supply line (144); and a sensor (150). The distributor (80) is positioned above the first tube bundle (78). The hood (88) covers the first tube bundle (78). The first supply line (142) is connected to the distributor (80) and an end of the second supply line (144) is positioned near the hood (88). The sensor (150) is configured and positioned to sense a level of liquid refrigerant (82) in the shell. The valve (122) regulates flow in the second supply line in response to the level of liquid refrigerant (82) from the sensor (150).

Abstract: A leak detection system of a heating, ventilating, and air conditioning (HVAC) system includes a sensor configured to detect a UV tracer in a monitored gas volume of the HVAC system. The leak detection system also includes a controller communicatively coupled to the sensor. The controller is configured to modify operation of the HVAC system in response to the sensor detecting the UV tracer in the monitored gas volume.

Abstract: The present disclosure relates to a heating, ventilating, and air conditioning (HVAC) system that includes a refrigerant circuit and a sensor configured to measure a refrigerant concentration external to the refrigeration circuit. The HVAC system also includes a controller that is communicatively coupled to the sensor and to an economizer. The controller is configured to control a flow of environmental air into the HVAC system. The controller is further configured to increase a ratio of the flow of environmental air relative to a flow of return air from a conditioned interior space of a building when the sensor measures the refrigerant concentration above a predetermined threshold concentration.

Abstract: The present disclosure relates to a refrigeration circuit that includes a controller communicatively coupled to a compressor, an expansion valve, and a sensor of the refrigeration circuit. The controller may activate the compressor and actuate the expansion valve such that the compressor is active while the expansion valve is closed. The controller may also measure a pressure of a refrigerant in the refrigeration circuit using the sensor while the compressor is active and the expansion valve is closed. Additionally, the controller may determine whether a refrigerant leak exists based on a maximum measurement time being reached or a time difference between a first time associated with the compressor being active while the expansion valve is closed and a second time associated with the measured pressure falling below a threshold value.