Abstract: Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect(s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging.

Abstract: Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect(s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging.

Abstract: Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect(s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging.

Abstract: The present invention is directed to a method and computer system for representing a dataset comprising N documents by computing a diffusion geometry of the dataset comprising at least a plurality of diffusion coordinates. The present method and system stores a number of diffusion coordinates, wherein the number is linear in proportion to N.

Abstract: The present invention is directed to a method and computer system for representing a dataset comprising N documents by computing a diffusion geometry of the dataset comprising at least a plurality of diffusion coordinates. The present method and system stores a number of diffusion coordinates, wherein the number is linear in proportion to N.

Abstract: Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect (s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging.

Abstract: Method and apparatus for detecting leaks in a fluid vessel. The apparatus comprises a pressure sensor for measuring a pressure difference between a reference cell and a sample cell. The sample cell is open to the fluid vessel. The method and apparatus detects a leak in the fluid vessel when the pressure difference exceeds a predetermined threshold.

Abstract: A hyper-spectral imaging system comprises imaging foreoptics (1020) to focus on a scene or object of interest (1010) and transfer the image of said scene or object (1010) onto the focal plane of a spatial light modulator (1030), a spatial light modulator (1030) placed at a focal plane of said imaging foreoptics (1020), an imaging dispersion device (1040) disposed to receive an output image of the spatial light modulator (1030), and an image collecting device disposed to receive the output of the imaging dispersion device (1040).

Abstract: The present invention is directed to a method and computer system for representing a dataset comprising N documents by computing a diffusion geometry of the dataset comprising at least a plurality of diffusion coordinates. The present method and system stores a number of diffusion coordinates, wherein the number is linear in proportion to N.

Abstract: An apparatus and method for multispectral imaging comprising an array of filters in a mosaic pattern, a sensor array and an acquisition and processing module. The sensor array being disposed to receive an image that has been filtered by the array of filters. The acquisition and processing module processes the output of the sensor array (or mosaic acquired data) to provide a processed image. The acquisition and processing module processes the mosaic acquired data by performing first interpolation on the mosaic acquired data by the sensor array to provide a first approximation and performing second interpolation on the values of the first approximation to provide a second approximation.

Abstract: An improved method and system for classifying tissue samples comprises determining a tissue type classification based on spectral data of training samples of known target classification. Denoised spectral data is generated from the spectral data based on the tissue type classification. A classifier is then trained using the denoised spectral data to classify the tissue samples.

Abstract: A spectral measurement device comprising an entrance aperture for receiving an electromagnetic energy and a mask located at the entrance aperture in the form of a two-dimensional encodement pattern. An optical element conditions the electromagnetic energy received from the mask for presentation to the spectral dispersion element and the and a spectral dispersion element disperses the electromagnetic energy in one or more dimensions. Additionally, the optical element conditions the dispersed electromagnetic energy onto an array of detector elements.

Abstract: A hyper-spectral analysis method for characterizing or distinguishing diverse elements within hyper-spectral images. A plurality of patches of pixels from within the hyper-spectral images are extracted as being patches around pixels of the elements to be characterized or distinguished. The statistics of spectra for each patch of pixels are computed. A first classifier is computed from frequency-wise standard deviation of the spectra in each patch and a set of second classifiers are computed from principal components of the spectral in each patch. A combined classifier is computed based on the output of the first classifier and at least one of the second classifiers. The elements are characterized or distinguished based on the output of at least one of the classifiers, preferably the combined classifier.

Abstract: A spectral measurement device comprising an entrance aperture for receiving an electromagnetic energy and a mask located at the entrance aperture in the form of a two-dimensional encodement pattern. An optical element conditions the electromagnetic energy received from the mask for presentation to the spectral dispersion element and the and a spectral dispersion element disperses the electromagnetic energy in one or more dimensions. Additionally, the optical element conditions the dispersed electromagnetic energy onto an array of detector elements.

Abstract: Encoded spatio-spectral information processing is performed using a system having a radiation source, wavelength dispersion device and two-dimensional switching array, such as digital micro-mirror array (DMA). In one aspect, spectral components from a sample are dispersed in space and modulated separately by the switching array, each element of which may operate according to a predetermined encoding pattern. The encoded spectral components can then be detected and analyzed. In a different aspect, the switching array can be used to provide a controllable radiation source for illuminating a sample with radiation patterns that have predetermined characteristics and separately encoded components. Various applications are disclosed.

Abstract: An adaptive digitally tuned light source is disclosed, in the form of a de-dispersive imaging spectrograph in both the visible and near infrared spectral regions. The devices are capable of illuminating a sample with appropriate energy-weighted spectral bands or spatio-spectral bands that relate only to the constituents of interest. The energy from each of the spectral resolution elements can be digitally modulated to provide a tuned weighted spectral output. A tuned light source device based on the present disclosure can be adapted for use in a conventional imaging microscope system to enable direct measure of spatio-spectral features of interest.

Abstract: Systems and methods for encoded spatio-spectral information processing are disclosed. In a specific aspect, the invention involves applying or embedding of digital information in the spectral profile of materials, such as inks and paints, to provide the functionality of bar codes or labels, and reading such information from objects. Recording of digital information is enabled onto or into physical media with or without the use of printed symbols, by spraying, mixing or enabling a specific chemical changes resulting in digital information being encoded onto or into carrying materials. Because the information is encoded in the spectral signatures of compositions of materials, the precise location, shape, orientation and arrangement of marks is generally not used in the process of decoding. Various applications are disclosed.

Abstract: A spectrometer (10) includes a two-dimensional array of modulatable micro-mirrors (18), a detector (20), and an analyzer (22). The array of micro-mirrors is positioned for receiving individual radiation components forming a part of an input radiation source. The micro-mirrors are modulated at different modulation rates in order to reflect individual radiation components therefrom at known and different modulation rates. The micro-mirror array combines a number of the reflected individual radiation components and reflects the combined components to the detector. The detector is oriented to receive the combined radiation components reflected from the array and is operable to create an output signal representative thereof. The analyzer is operably coupled with the detector to receive the output signal and to analyze at least some of the individual radiation components making up the combined reflection.

Abstract: Encoded spatio-spectral information processing is performed using a system having a radiation source, wavelength dispersion device and two-dimensional switching array, such as digital micro-mirror array (DMA). In one aspect, spectral components from a sample are dispersed in space and modulated separately by the switching array, each element of which may operate according to a predetermined encoding pattern. The encoded spectral components can then be detected and analyzed. In a different aspect, the switching array can be used to provide a controllable radiation source for illuminating a sample with radiation patterns that have predetermined characteristics and separately encoded components. Various applications are disclosed.

Abstract: A spectrometer (10) includes a two-dimensional array of modulatable micro-mirrors (18), a detector (20), and an analyzer (22). The array of micro-mirrors is positioned for receiving individual radiation components forming a part of an input radiation source. The micro-mirrors are modulated at different modulation rates in order to reflect individual radiation components therefrom at known and different modulation rates. The micro-mirror array combines a number of the reflected individual radiation components and reflects the combined components to the detector. The detector is oriented to receive the combined radiation components reflected from the array and is operable to create an output signal representative thereof. The analyzer is operably coupled with the detector to receive the output signal and to analyze at least some of the individual radiation components making up the combined reflection.