Patents by Inventor William Greenleaf

William Greenleaf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD TO PERFORM HIGH-THROUGHPUT SINGLE CELL GENOMIC AND PHENOTYPIC ANALYSES
    Publication number: 20210261953
    Abstract: The invention provides methods of performing multi-parameter analysis of single cells. Specifically, the present invention is based, in part, on leveraging a separation of reaction volume scales to conduct high-throughput single cell multi-parameter measurements and library preparation on the same single cell using double emulsion micro-droplets and sorting using flow cytometry.
    Type: Application
    Filed: July 1, 2019
    Publication date: August 26, 2021
    Inventors: Polly Fordyce, Kara Brower, Sandy Klemm, William Greenleaf
  • Motion resolved molecular sequencing
    Patent number: 7556922
    Abstract: Methods are provided for determining the sequence of a polynucleotide by tracking the motion of a nucleotide-selective, processive enzyme along a template, in a reaction mixture that alters the enzyme movement in a base specific manner. The movement trace of the enzyme is collected, and arranged in temporal order. The enzyme movement traces are correlated with the reaction conditions, and from these characteristic signals, the nucleotide sequence is derived.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: July 7, 2009
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Steven M. Block, William Greenleaf
  • Motion resolved molecular sequencing
    Publication number: 20080020392
    Abstract: Methods are provided for determining the sequence of a polynucleotide by tracking the motion of a nucleotide-selective, processive enzyme along a template, in a reaction mixture that alters the enzyme movement in a base specific manner. The movement trace of the enzyme is collected, and arranged in temporal order. The enzyme movement traces are correlated with the reaction conditions, and from these characteristic signals, the nucleotide sequence is derived.
    Type: Application
    Filed: March 21, 2007
    Publication date: January 24, 2008
    Inventors: Steven Block, William Greenleaf