Abstract: A method for therapeutically affecting the circulation of blood in a person in combination with or with medication to treat a medical condition includes the steps of administering a composition for treating a circulatory condition, providing a source of high pressure air in fluid communication with a plurality of air pressure actuated valves, each of the valves mounted on, and in fluid communication with, an inflatable bladder disposed within a cuff removably attached about at least one of the feet, calves, thighs, buttocks of the person; providing a source of low pressure aft in fluid communication with the plurality of valves, wherein a constant pressure is exerted against said valves; and controlling inflation of the bladders in a predetermined sequence, magnitude of inflation pressure and period of time during a cardiac cycle of the person and as a function of the person's physiological reaction to said composition.

Abstract: A method for therapeutically affecting the circulation of blood in a person in combination with or with medication to treat a medical condition includes the steps of administering a composition for treating a circulatory condition, providing a source of high pressure air in fluid communication with a plurality of air pressure actuated valves, each of the valves mounted on, and in fluid communication with, an inflatable bladder disposed within a cuff removably attached about at least one of the feet, calves, thighs, buttocks of the person; providing a source of low pressure air in fluid communication with said plurality of valves, wherein a constant pressure is exerted against said valves; and controlling inflation of said bladders in a predetermined sequence, magnitude of inflation pressure and period of time during a cardiac cycle of the person and as a function of said person's physiological reaction to said composition.

Abstract: A method for therapeutically affecting the circulation of blood in a person in combination with or with medication to treat a medical condition includes the steps of administering a composition for treating a circulatory condition, providing a source of high pressure air in fluid communication with a plurality of air pressure actuated valves, each of the valves mounted on, and in fluid communication with, an inflatable bladder disposed within a cuff removably attached about at least one of the feet, calves, thighs, buttocks of the person; providing a source of low pressure air in fluid communication with said plurality of valves, wherein a constant pressure is exerted against said valves; and controlling inflation of said bladders in a predetermined sequence, magnitude of inflation pressure and period of time during a cardiac cycle of the person and as a function of said person's physiological reaction to said composition.

Abstract: A portable computing device or microprocessor/storage system including temperature sensors used to collect temperature readings of a breast tissue of a subject. The device would collect data from the sensors at regular time intervals over a period of time. All of the generated temperature data is stored in the portable computing or storage device. The sensors are placed on the greatest areas of interest on the breast, based on where most cancers develop, by using a sensor placeholder. The sensor placeholder would be lobate shaped, with the sensor placeholder aligning with the glandular regions of the breast where cancers are most likely to develop. The temperature data is then analyzed by one or more classifier systems and classified as either suspect or non-suspect tissue.

Abstract: A portable computing device or microprocessor/storage system including temperature sensors used to collect temperature readings of a breast tissue of a subject. The device would collect data from the sensors at regular time intervals over a period of time. All of the generated temperature data is stored in the portable computing or storage device. The sensors are placed on the greatest areas of interest on the breast, based on where most cancers develop, by using a sensor placeholder. The sensor placeholder would be lobate shaped, with the sensor placeholder aligning with the glandular regions of the breast where cancers are most likely to develop. The temperature data is then analyzed by one or more classifier systems and classified as either suspect or non-suspect tissue.

Abstract: A device for providing improved classification of breast tissue wherein the tissue is classified as one of cancerous and non-cancerous tissue includes sensors for sensing temperature of a subject breast tissue over a predetermined period and generating signals in response thereto and a computer operatively connected to the sensors for receiving and manipulating the signals operatively associated with a normalizer for applying a normalization to each the signal by a function of X/Y where X is one temperature reading of one of the signals for a particular subject and Y is the maximum temperature obtained from a predetermined number sets of temperature readings obtained a plurality of subject breast tissue from the subject to provide a set of normalized signals used by a trained artificial classifier to produce a signal indicative of cancerous and non-cancerous tissue of the subject.

Abstract: A device for providing improved classification of breast tissue wherein the tissue is classified as one of cancerous and non-cancerous tissue includes sensors for sensing temperature of a subject breast tissue over a predetermined period and generating signals in response thereto and a computer operatively connected to the sensors for receiving and manipulating the signals operatively associated with a normalizer for applying a normalization to each the signal by a function of X/Y where X is one temperature reading of one of the signals for a particular subject and Y is the maximum temperature obtained from a predetermined number sets of temperature readings obtained a plurality of subject breast tissue from the subject to provide a set of normalized signals used by a trained artificial classifier to produce a signal indicative of cancerous and non-cancerous tissue of the subject.

Abstract: A method for therapeutically affecting the circulation of blood in a person in combination with or with medication to treat a medical condition includes the steps of administering a composition for treating a circulatory condition, providing a source of high pressure air in fluid communication with a plurality of air pressure actuated valves, each of the valves mounted on, and in fluid communication with, an inflatable bladder disposed within a cuff removably attached about at least one of the feet, calves, thighs, buttocks of the person; providing a source of low pressure air in fluid communication with said plurality of valves, wherein a constant pressure is exerted against said valves; and controlling inflation of said bladders in a predetermined sequence, magnitude of inflation pressure and period of time during a cardiac cycle of the person and as a function of said person's physiological reaction to said composition.

Abstract: The invention relates to the discovery that formulations of Lachesis venom decrease circulating TNF-? levels in mammals including humans, and that administration of Lachesis venom-containing formulations to mammals suffering from sepsis, parasitic infection, cisplatin nephrotoxicity, rheumatoid arthritis, cancer and AIDS mitigates symptoms associated with these conditions.

Abstract: The invention relates to the development of apparatuses and methods for healing wounds that combine use of a high glycerin-content hydrogel dressing with negative pressure for removing exudate from a wound. In some embodiments, apparatuses and methods further include a photon-emitting device that delivers near infrared stimulation to the wound for further accelerating wound healing. The apparatuses and methods described herein can be used to heal a variety of wounds, including acute wounds, severe burns, orthopedic and traumatic wounds (e.g, flap and meshed graft), skin resurfacing procedure wounds, and neuropathic wounds (e.g., diabetic pressure ulcers). The hydrogel dressing is capable of absorbing substantial amounts of fluids from stimulated wet wounds as well as donating substantial amounts of fluids to dry or necrotic wounds, depending upon the moisture content and nature of the substrate to which it is applied.

Abstract: An apparatus and method of use thereof for identifying and monitoring women at risk of developing OSE-derived carcinomas is provided. The apparatus includes an introducer needle configured to be capable of insertion into a female such that a terminal end of the needle is positioned adjacent an ovary of the female, a microendoscope having an optic fiber which is operably insertable into the needle in a manner to enable an image of the ovary to be obtained therethrough, and a tissue removing member operably co-insertable into the needle with the optic fiber therein to enable removal of ovarian tissue cells with minimal deleterious effect to the ovary.

Abstract: An apparatus and method of use thereof for identifying and monitoring women at risk of developing OSE-derived carcinomas is provided. The apparatus includes an introducer needle configured to be capable of insertion into a female such that a terminal end of the needle is positioned adjacent an ovary of the female, a microendoscope having an optic fiber which is operably insertable into the needle in a manner to enable an image of the ovary to be obtained therethrough, and a tissue removing member operably co-insertable into the needle with the optic fiber therein to enable removal of ovarian tissue cells with minimal deleterious effect to the ovary.

Abstract: An apparatus and method of use thereof for identifying and monitoring women at risk of developing OSE-derived carcinomas is provided. The apparatus includes an introducer needle configured to be capable of insertion into a female such that a terminal end of the needle is positioned adjacent an ovary of the female, a microendoscope having an optic fiber which is operably insertable into the needle in a manner to enable an image of the ovary to be obtained therethrough, and a tissue removing member operably co-insertable into the needle with the optic fiber therein to enable removal of ovarian tissue cells with minimal deleterious effect to the ovary.

Abstract: A system detecting cancerous and precancerous pathologies includes a blood flow affecting compound introducible into an arterial and venous area of tissue in an area to be examined, a temperature sensor operably disposed on the area capable of sensing and generating a signal indicative of temperature sensed, and a computer-based device operably associated with the temperature sensor for receiving and manipulating the signal in a manner for generating a thermo-physiological data signal indicative of precancerous and cancerous conditions in the sensed area.

Abstract: An apparatus and method of use thereof for identifying and monitoring women at risk of developing OSE-derived carcinomas is provided. The apparatus includes an introducer needle configured to be capable of insertion into a female such that a terminal end of the needle is positioned adjacent an ovary of the female, a microendoscope having an optic fiber which is operably insertable into the needle in a manner to enable an image of the ovary to be obtained therethrough, and a tissue removing member operably co-insertable into the needle with the optic fiber therein to enable removal of ovarian tissue cells with minimal deleterious effect to the ovary.

Abstract: An apparatus for detection of precancerous and cancerous conditions in a breast is provided and includes a computer for digitizing at least one of a mammogram image data and a (scinti)mammogram image data of a breast, computer-based software operably associated with the computer based means for manipulating at least one of said digitized mammogram image data and said digitized (scinti)mammogram image data and generating at least one of a mammogram ROI image and a (scinti)mammogram ROI image data indicative of precancerous and cancerous condition, and monitor operably associated with the computer based means for concurrently visually displaying at least one of said digitized mammogram image data and said digitized (scinti)mammogram image data and said mammogram ROI image and said (scinti)mammogram ROI image data in a superimposed manner.

Abstract: This invention relates to a medical pumping apparatus. The medical pumping apparatus continuously and automatically monitors fill status of the venous plexus and flow rate from the venous plexus and continuously and automatically controls the pressure and cycle rate of a pump capable of cyclically applying pressure to a part of the human body for the purpose of maximizing blood transfer therein.

Abstract: This invention relates to a medical pumping apparatus which utilizes a neural network. The medical pumping apparatus continuously and automatically monitors fill status of the venous plexus and flow rate from the venous plexus and continuously and automatically controls the pressure and cycle rate of a pump capable of cyclically applying pressure to a part of the human body for the purpose of maximizing blood transfer therein.

Abstract: The present invention relates to a device for detecting and monitoring physiological conditions in mammalian tissue, and method for using the same. The device includes sensors for sensing physiological conditions and generating signals in response thereto and processor operatively associated with the sensors for receiving and manipulating the signals to produce a generalization indicative of normal and abnormal physiological condition of mammalian tissue. The processor is characterized to include a neural network having a predetermined solution spaced memory, the solution space memory including regions indicative of two (2) or more physiological conditions, wherein the generalization is characterized by the signals projected into the regions.

Abstract: Gold sand resulting from the nitric acid treatment of silver refinery slimes is purified by washing with hydrochloric acid under controlled operating conditions. Platinum and other precious metals and impurities are selectively separated from the gold sand leaving a gold sand which is more efficiently refined.