Abstract: The present invention aims to provide a method for producing a cartilage tissue, which enables production of a cartilage tissue having an appropriate thickness, form, and mechanical strength, and a cartilage tissue produced by the method for producing a cartilage tissue. Provided is a method for producing a cartilage tissue including a step of seeding a collagenase-treated cartilage tissue piece in the form of a block 50 to 1,000 ?m on a side onto a porous substrate composed of a bioabsorbable material.

Abstract: An improved envelope construction comprises in general an envelope unit, a sealing unit, and a tear strip unit. The envelope unit comprises an envelope body member having a flap portion with a central segment provided with the sealing unit and two generally triangular end segments separated from the central segment by strips of perforations. The sealing unit and the tear strip unit are operatively disposed on the flap portion. The tear strip unit extends across and has a length that can project beyond the flap portions. The opposite ends of the tear strip member are provided with globular elements to facilitate the user's grasp of a selected end of the tear strip to open the envelope.