Patents by Inventor William J. Ray
William J. Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240150332Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.Type: ApplicationFiled: September 19, 2023Publication date: May 9, 2024Inventors: Paolo PEVARELLO, William J. RAY, Mary HAMBY, Yaima Luzardo LIGHTFOOT, Philip JONES, Russell THOMAS, Chiara LIBERATI, Domenica TORINO, Valentina CUSANO, Francesco PISCITELLI, Ali Munaim YOUSIF, Silvia BOVOLENTA
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Patent number: 11958839Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.Type: GrantFiled: September 22, 2021Date of Patent: April 16, 2024Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, GOLGI NEUROSCIENCES, S.R.L.Inventors: Paolo Pevarello, William J. Ray, Mary Hamby, Yaima Luzardo Lightfoot, Philip Jones, Russell Thomas, Chiara Liberati, Domenica Torino, Valentina Cusano, Francesco Piscitelli, Ali Munaim Yousif, Silvia Bovolenta
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Patent number: 11962017Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.Type: GrantFiled: January 25, 2023Date of Patent: April 16, 2024Assignee: Printed Energy Pty LtdInventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
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Publication number: 20240109780Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.Type: ApplicationFiled: May 1, 2023Publication date: April 4, 2024Inventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
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Patent number: 11753381Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.Type: GrantFiled: September 25, 2020Date of Patent: September 12, 2023Assignee: Board of Regents, The University of Texas SystemInventors: Richard T. Lewis, Matthew Michael Hamilton, William J. Ray, Fernando Alvarez, Dana E. Pfaffinger, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
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Publication number: 20230282839Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.Type: ApplicationFiled: January 25, 2023Publication date: September 7, 2023Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
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Patent number: 11718612Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.Type: GrantFiled: September 8, 2020Date of Patent: August 8, 2023Assignee: Board of Regents, The University of Texas SystemInventors: Richard T. Lewis, Matthew Hamilton, William J. Ray, Fernando Alvarez, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
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Patent number: 11690850Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.Type: GrantFiled: November 19, 2020Date of Patent: July 4, 2023Assignee: Board of Regents, The University of Texas SystemInventors: Richard T. Lewis, Matthew Hamilton, William J. Ray, Fernando Alvarez, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
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Publication number: 20230207836Abstract: A printed energy storage device includes a first electrode including zinc, a second electrode including manganese dioxide, and a separator between the first electrode and the second electrode, the first electrode, second, electrode, and separator printed onto a substrate. The device may include a first current collector and/or a second current collector printed onto the substrate. The energy storage device may include a printed intermediate layer between the separator and the first electrode. The first electrode, and the second electrode may include 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode and the second electrode may include an electrolyte having zinc tetrafluoroborate (ZnBF4) and 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode, the second electrode, the first current collector, and/or the second current collector can include carbon nanotubes. The separator may include solid microspheres.Type: ApplicationFiled: November 1, 2022Publication date: June 29, 2023Inventors: Vera N. Lockett, John G. Gustafson, Alexandra E. Hartman, Mark D. Lowenthal, William J. Ray
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Patent number: 11673811Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.Type: GrantFiled: July 16, 2021Date of Patent: June 13, 2023Assignee: Printed Energy Pty LtdInventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
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Publication number: 20230159508Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.Type: ApplicationFiled: August 17, 2022Publication date: May 25, 2023Inventors: Richard T. LEWIS, Matthew HAMILTON, William J. RAY, Fernando ALVAREZ, Naphtali REYNA, Suyambu Kesava Vijayan RAMASWAMY
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Patent number: 11637292Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.Type: GrantFiled: July 12, 2021Date of Patent: April 25, 2023Assignee: Printed Energy Pty LtdInventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
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Patent number: 11502311Abstract: A printed energy storage device includes a first electrode including zinc, a second electrode including manganese dioxide, and a separator between the first electrode and the second electrode, the first electrode, second, electrode, and separator printed onto a substrate. The device may include a first current collector and/or a second current collector printed onto the substrate. The energy storage device may include a printed intermediate layer between the separator and the first electrode. The first electrode, and the second electrode may include 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode and the second electrode may include an electrolyte having zinc tetrafluoroborate (ZnBF4) and 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode, the second electrode, the first current collector, and/or the second current collector can include carbon nanotubes. The separator may include solid microspheres.Type: GrantFiled: May 15, 2020Date of Patent: November 15, 2022Assignee: PRINTED ENERGY Pty LtdInventors: Vera N. Lockett, John G. Gustafson, Alexandra E. Hartman, Mark D. Lowenthal, William J. Ray
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Publication number: 20220259191Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.Type: ApplicationFiled: September 22, 2021Publication date: August 18, 2022Inventors: Paolo PEVARELLO, William J. RAY, Mary HAMBY, Yaima Luzardo LIGHTFOOT, Philip JONES, Russell THOMAS, Chiara LIBERATI, Domenica TORINO, Valentina CUSANO, Francesco PISCITELLI, Ali Munaim YOUSIF, Silvia BOVOLENTA
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Publication number: 20220149232Abstract: A light emitting structure uses an extruded mixture of a fluorescent material and a transparent plastic to form a thin flexible substrate. The extrusion, using a slot die, forms a thin flexible film having very smooth surfaces with a uniform thickness. A transparent first conductive layer is then printed over the substrate. Pre-formed micro-LEDs are then printed over the first conductive layer, where the bottom electrodes of the LEDs contact the first conductive layer. A dielectric layer is deposited between the LEDs and exposes the top electrode of the LEDs. A second conductive layer, which may be transparent or reflective, is printed over the LEDs to electrically connect at least some of the LEDs in parallel. Primary light emitted from the LEDs energizes the fluorescent material in the substrate to emit secondary light from the substrate. Blue LED light may combine with the secondary light to create a wide gamut of colors, such as white.Type: ApplicationFiled: October 28, 2021Publication date: May 12, 2022Inventor: William J. Ray
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Publication number: 20220041456Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.Type: ApplicationFiled: July 16, 2021Publication date: February 10, 2022Inventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
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Publication number: 20220006101Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.Type: ApplicationFiled: July 12, 2021Publication date: January 6, 2022Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
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Patent number: 11155538Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.Type: GrantFiled: July 23, 2020Date of Patent: October 26, 2021Assignees: Board of Regents, The University of Texas System, Axxam S.p.A.Inventors: Paolo Pevarello, William J. Ray, Mary Hamby, Yaima Luzardo Lightfoot, Philip Jones, Russell Thomas, Chiara Liberati, Domenica Torino, Valentina Cusano, Francesco Piscitelli, Ali Munaim Yousif, Silvia Bovolenta
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Patent number: 11066306Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.Type: GrantFiled: February 21, 2019Date of Patent: July 20, 2021Assignee: Printed Energy Pty LtdInventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
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Patent number: 11063265Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.Type: GrantFiled: August 8, 2019Date of Patent: July 13, 2021Assignee: Printed Energy Pty LtdInventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli