Abstract: Disclosed herein are methods of producing substantially pathogen-free plants of the genus Cannabis and pathogen-free plants and clones produced therefrom. One embodiment of the method comprises pretreating a progenitor plant of the genus Cannabis, surface sterilizing a shoot segment of the pretreated plant with a bleach solution, excising a meristematic tip of the shoot segment, and transferring the meristematic tip into a culturing plate comprising a supplemented Murashige and Skoog culture medium for further culturing. The supplemented Murashige and Skoog culture medium can comprise benzyladenine, naphthaleneacetic acid, gibberellic acid, or a combination thereof.

Abstract: Disclosed herein are methods of producing substantially pathogen-free plants of the genus Cannabis and pathogen-free plants and clones produced therefrom. One embodiment of the method comprises heating a progenitor plant of the genus Cannabis within a heating chamber resulting in a heat-treated plant, surface sterilizing a shoot segment of the heat-treated plant with a bleach solution, excising a meristematic tip of the shoot segment, and transferring the meristematic tip into a culturing plate comprising a supplemented Murashige and Skoog culture medium for further culturing. The supplemented Murashige and Skoog culture medium can comprise benzyladenine, naphthaleneacetic acid, gibberellic acid, or a combination thereof.

Abstract: Ice for use in a beverage, wherein the ice comprises a core, an active zone, an external surface, and caffeine. The ice particle has a depth from each point of the external surface extending perpendicularly inwards. It also has a total particle mass. The caffeine in the ice particle has a total caffeine mass, and the ice particle has an ice caffeine concentration equal to the total caffeine mass divided by the total particle mass. The active zone includes at least 40% of the total caffeine mass and local caffeine concentrations of at least 150% of the ice caffeine concentration. At least 67% of the total caffeine mass is contained within a caffeine depth in millimeters from the external surface no greater than 1.06 times the cube root of the total particle mass in grams. The core has local caffeine concentrations of less than 150% of the ice caffeine concentration.

Abstract: A system and method for detecting network intrusions using one or more statistical models and a generalized likelihood ratio test (GLRT) is provided. The system includes a computer system and a network intrusion detection engine executed by the computer system. To detect network intrusions, the system receives network traffic data, computes a likelihood using one or more statistical models, such as an Markov-modulated Poisson process, and processes the traffic data using a GLRT. The statistical models are used to assess the likelihood of seeing a particular pattern of network traffic. The GLRT is used to classify a particular pattern as either indicative of an attack or not indicative of an attack. The system could apply one or more types of statistical models, such as in a flexible multi-tiered approach.

Abstract: Tuning a programmable power line filter, the power line filter including a live line, a neutral line, and a ground line connected to input terminals of the filter on an input side of the filter, the live line and the neutral line connected through inductors in the filter to output terminals on an output side of the filter, X-capacitors selectably connected through tuning switches between the live line and the neutral line, Y-capacitors selectably connected through tuning switches between the live line and ground and/or between the neutral line and ground, and a tuning control circuit connected to the tuning switches and selectably connected through one or more programming switches to the load, including measuring by the tuning control circuit the input impedance of the load and programming by the tuning control circuit the tuning switches in dependence upon the input impedance of the load.

Abstract: Tuning a programmable power line filter, the power line filter including a live line, a neutral line, and a ground line connected to input terminals of the filter on an input side of the filter, the live line and the neutral line connected through inductors in the filter to output terminals on an output side of the filter, X-capacitors selectably connected through tuning switches between the live line and the neutral line, Y-capacitors selectably connected through tuning switches between the live line and ground and/or between the neutral line and ground, and a tuning control circuit connected to the tuning switches and selectably connected through one or more programming switches to the load, including measuring by the tuning control circuit the input impedance of the load and programming by the tuning control circuit the tuning switches in dependence upon the input impedance of the load.

Abstract: The present invention provides methods for reducing body weight. In particular, the present invention provides methods for reducing body weight by administering a composition comprising a forskolin 1?,9?-carbonate compound of the formula: where R1 is hydrogen or a carbonyl group.

Abstract: An administration method is provided, in which a composition comprising a forskolin 1?,9?-carbonate compound is administered to a human subject. According to an embodiment, the forskolin 1?,9?-carbonate compound has a skeletal structure of 8,13-epoxy-1?,6?,7?,9?-tetrahydroxylabd-14-en-11-one. A carbonyl group links the 1-position hydroxy oxygen and the 9-position hydroxy oxygen to one another for forming a carbonate ester ring. Hydrogen is appended to the 6-position hydroxy oxygen. A hydrogen or an acetyl group is appended to the 7-position hydroxy oxygen.

Abstract: A compound is provided for increasing the concentration of a parent isoflavone in a subject in vivo. The parent isoflavone has a skeletal structure including a 5 position and a 7 position, a 5 alkyl group, and a 7-hydroxy group with a 7-hydroxy oxygen appended to the 7 position and a 7-hydroxy hydrogen appended to the 7-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent isoflavone, with a 5 position and a 7 position corresponding to the 5 and 7 positions respectively of the parent isoflavone. An alkyl group is appended to the 5 position. A promoiety is appended to the 7-hydroxy oxygen of the substrate as a substitute for the 7-hydroxy hydrogen of the parent isoflavone the promoiety and the 7-hydroxy oxygen establishing an alkylcarbonate ester. A related method also is provided.

Abstract: A compound is provided for increasing the concentration of a parent isoflavone in a subject in vivo. The parent isoflavone has a skeletal structure including a 5 position and a 7 position, a 5 alkyl group, and a 7-hydroxy group with a 7-hydroxy oxygen appended to the 7 position and a 7-hydroxy hydrogen appended to the 7-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent isoflavone, with a 5 position and a 7 position corresponding to the 5 and 7 positions respectively of the parent isoflavone. An alkyl group is appended to the 5 position. A promoiety is appended to the 7-hydroxy oxygen of the substrate as a substitute for the 7-hydroxy hydrogen of the parent isoflavone, the promoiety and the 7-hydroxy oxygen establishing an alkylcarbonate ester. A related method also is provided.

Abstract: A compound is provided for increasing the concentration of a parent androgen in a subject in vivo. The parent androgen has a skeletal structure including a 1 position and a 17 position, a 17&bgr;-hydroxy group comprising a 17&bgr;-hydroxy oxygen appended to the 17 position, and a 17&bgr;-hydroxy hydrogen appended to the 17&bgr;-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent androgen. It includes a 1 position and a 17 position corresponding to the 1 and 17 positions respectively of the parent androgen. The substrate has a carbon—carbon double bond at the 1 position. The compound also has a promoiety appended to the 17&bgr;-hydroxy oxygen of the substrate as a substitute for the 17&bgr;-hydroxy hydrogen of the parent androgen. The promoiety includes, and preferably consists of, an alkylcarbonate ester. A related method also is provided.

Abstract: A compound is provided for increasing the concentration of a parent isoflavone in a subject in vivo. The parent isoflavone has a skeletal structure including a 5 position and a 7 position, a 5 alkyl group, and a 7-hydroxy group with a 7-hydroxy oxygen appended to the 7 position and a 7-hydroxy hydrogen appended to the 7-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent isoflavone, with a 5 position and a 7 position corresponding to the 5 and 7 positions respectively of the parent isoflavone. An alkyl group is appended to the 5 position. A promoiety is appended to the 7-hydroxy oxygen of the substrate as a substitute for the 7-hydroxy hydrogen of the parent isoflavone, the promoiety and the 7-hydroxy oxygen establishing an alkylcarbonate ester. A related method also is provided.

Abstract: A composition is provided including a first prohormone for increasing the concentration of a Class I parent androgen in a subject in vivo, and a second prohormone for increasing the concentration of a Class II parent androgen in the subject in vivo. The first prohormone includes a first carbon-carbon double bond at the 1 position, and a first 17&bgr;-hydroxy oxygen appended to the 17 position. The first prohormone further includes a first 17-position promoiety is appended to the first 17&bgr;-hydroxy oxygen as a substitute for the 17&bgr;-hydroxy hydrogen of the Class I parent androgen. The second prohormone includes a second carbon-carbon double bond at the 4 position and a second 17&bgr;-hydroxy oxygen appended to the 17 position. The second prohormone also includes a second 17-position promoiety appended to the second 17&bgr;-hydroxy oxygen as a substitute for the 17&bgr;-hydroxy hydrogen of the Class II parent androgen.

Abstract: A compound is provided for increasing the concentration of a parent androgen in a subject in vivo. The parent androgen has a skeletal structure including a 4 position and a 17 position. It has a 17&bgr;-hydroxy group that includes a 17&bgr;-hydroxy oxygen appended to the 17 position and a 17&bgr;-hydroxy hydrogen appended to the 17&bgr;-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent androgen, wherein the substrate includes a 4 position and a 17 position corresponding to the 4 and 17 positions respectively of the parent androgen. The substrate according to one aspect of the invention includes a carbon-carbon double bond at the 4 position. The skeletal structure of the parent androgen embodied in the substrate being selected from the group consisting of androst-4-ene-3&agr;,17&bgr;-diol, androst-4-ene-3&bgr;,17&bgr;-diol, and mixtures thereof, or estr-4-ene-3&agr;,17&bgr;-diol, estr-4-ene-3&bgr;,17&bgr;-diol, and mixtures thereof, or combinations of these.

Abstract: A compound is provided for increasing the concentration of a parent androgen in a subject in vivo. The parent androgen has a skeletal structure including a 1 position and a 17 position, a 17&bgr;-hydroxy group comprising a 17&bgr;-hydroxy oxygen appended to the 17 position, and a 17&bgr;-hydroxy hydrogen appended to the 17&bgr;-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent androgen. It includes a 1 position and a 17 position corresponding to the 1 and 17 positions respectively of the parent androgen. The substrate has a carbon-carbon double bond at the 1 position. The compound also has a promoiety appended to the 17&bgr;-hydroxy oxygen of the substrate as a substitute for the 17&bgr;-hydroxy hydrogen of the parent androgen. The promoiety includes, and preferably consists of, an alkylcarbonate ester. A related method also is provided.

Abstract: A compound for supplementing the concentration of a parent androgen in a subject in vivo, wherein the parent androgen has a skeletal structure including a 17 position and the parent androgen further has a 17&bgr;-hydroxy group comprising a 17&bgr;-hydroxy hydrogen appended to the 17 position. The compound comprises a substrate having the skeletal structure of the parent androgen including a 17 position corresponding to the 17 position of the parent androgen, and a promoiety comprising an alkoxymethyl ether appended to the 17 position of the substrate as a substitute for the 17&bgr;-hydroxy hydrogen. Related compounds and methods also are disclosed.

Abstract: Methods and apparatus for making paint roller covers by spirally wrapping a strip of hot thermoplastic film onto an exterior surface of a thermoplastic tubular form and spirally wrapping fabric strip having a thermoplastic backing onto the spiral wound strip of thermoplastic film while the thermoplastic film is still sufficiently hot to cause the thermoplastic film to flow into interstices in the fabric backing and permanently bond the fabric strip to the exterior surface of the tubular form. The tubular form may either comprise a plurality of preformed tubes or be formed by spirally wrapping a continuous length of core strip material around a mandrel while maintaining the adjacent edges of the core strip material in closely spaced, nonoverlapping relation to form a spiral seam between the core strip edges.

Abstract: A paint roller cover with thermoplastic core and method and apparatus for making same by spirally wrapping a strip of hot extruded thermoplastic film onto an exterior surface of hollow thermoplastic tubing and spirally wrapping a strip of fabric having a thermoplastic backing onto the spiral wound strip of thermoplastic film while the thermoplastic film is still sufficiently hot to cause the thermoplastic film to flow into interstices in the thermoplastic backing of the fabric and permanently bond the fabric to the exterior surface of the tubing. The fabric covered tubing is then cooled and separated into a plurality of individual lengths of fabric covered tubes.

Abstract: Exercised systems are disclosed which are adapted for connection to at least one structural component of a building to provide a framework for kinesthetic exercises. Structures are disclosed which define a plurality of fixable locations for the connection of various kinesthetic exercising apparatus in arrangements suitable for a variety of kinesthetic exercises. The systems further include mechanisms for quick releasable and replaceable coupling of exercise apparatus in a freely rotatable manner to accommodate a wide range of body motions.

Abstract: A method and apparatus for making a paint roller cover by spirally wrapping a strip of hot extruded thermoplastic film onto an exterior surface of hollow thermoplastic tubing and spirally wrapping a strip of fabric having a thermoplastic backing onto the spiral wound strip of thermoplastic film while the thermoplastic film is still sufficiently hot to cause the thermoplastic film to flow into interstices in the thermoplastic backing of the fabric and permanently bond the fabric to the exterior surface of the tubing. The fabric covered tubing is then cooled and separated into a plurality of individual lengths of fabric covered tubes.