Patents by Inventor William K. Hagmann

William K. Hagmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Steroidal glycolipids as host resistance stimulators against viral infection
    Patent number: 4970199
    Abstract: Disclosed are steroidal derivatives of glycolipids, in which steroids are bridged, via a medium length hydrocarbon chain, to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses in combination with an anti-AIDS drug, that protect an immunocomprimised hot, particularly resulting from an AIDS-related virus, against opportunistic infection.
    Type: Grant
    Filed: July 10, 1989
    Date of Patent: November 13, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Philippe L. Durette, William K. Hagmann, Mitree M. Ponpipom
  • Steroidal glycolipids as host resistance stimulators against viral infection
    Patent number: 4942154
    Abstract: Disclosed are steroidal derivatives of glycolipids, in which steroids are bridged, via a medium length hydrocarbon chain, to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses that protect an immunocompromised host, particularly resulting from an AIDS-related virus, against opportunistic infection.
    Type: Grant
    Filed: June 18, 1987
    Date of Patent: July 17, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Philippe L. Durette, Mitree M. Ponpipom, William K. Hagmann
  • Tetrazolyl derivatives of beta-lactams useful as elastase inhibitors
    Patent number: 4845088
    Abstract: Tetrazolyl derivatives of .beta.-lactams are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: June 5, 1987
    Date of Patent: July 4, 1989
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, William K. Hagmann, Paul E. Finke, Shrenik K. Shah
  • Substituted 1-oxa-dethiacephalosporins as anti-inflammatory and antidegenerative agents
    Patent number: 4717722
    Abstract: Substituted 1-oxa-dethiacephalosporins are found to be effective elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: May 7, 1984
    Date of Patent: January 5, 1988
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, William K. Hagmann
  • Tetrazolyl derivatives of .beta.-lactams useful as elastase inhibitors
    Patent number: 4699904
    Abstract: Tetrazolyl derivatives of .beta.-lactams are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: July 1, 1985
    Date of Patent: October 13, 1987
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, Paul E. Finke, William K. Hagmann, Shrenik K. Shah
  • Steroidal glycolipids
    Patent number: 4652637
    Abstract: Described are derivatives of glycolipids with substituted steroids bridged via a medium length hydrocarbon chain to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses. These compounds protect an immunocompromised human or animal host against opportunistic infection by virtue of their immunostimulant properties.
    Type: Grant
    Filed: November 25, 1985
    Date of Patent: March 24, 1987
    Assignee: Merck & Co., Inc.
    Inventors: William K. Hagmann, Mitree M. Ponpipom
  • Steroidal glycolipids as host resistance stimulators
    Patent number: 4652553
    Abstract: Described are derivatives of glycolipids with substituted steroids bridged via a medium length hydrocarbon chain to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses. These compounds protect an immunocompromised human or animal host against opportunistic infection by virtue of their immunostimulant properties.
    Type: Grant
    Filed: November 25, 1985
    Date of Patent: March 24, 1987
    Assignee: Merck & Co., Inc.
    Inventors: William K. Hagmann, Philippe L. Durette, Mitree M. Ponpipom
  • Resolution of racemic derivatives of 5-(1-methyl-5-methylthiopyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrro le-2-carboxylic acid and analogs
    Patent number: 4622407
    Abstract: Racemic mixture of derivatives of 5-(1-methyl-5-methylthiopyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole -2-carboxylic acid and analogs were resolved into pure l- or d-isomers via concomitant isomerization and functional crystallization.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: November 11, 1986
    Assignee: Merck & Co., Inc.
    Inventor: William K. Hagmann