Patents by Inventor William Klein
William Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12002164Abstract: Various methods and systems are provided for authoring and presenting 3D presentations. Generally, an augmented or virtual reality device for each author, presenter and audience member includes 3D presentation software. During authoring mode, one or more authors can use 3D and/or 2D interfaces to generate a 3D presentation that choreographs behaviors of 3D assets into scenes and beats. During presentation mode, the 3D presentation is loaded in each user device, and 3D images of the 3D assets and corresponding asset behaviors are rendered among the user devices in a coordinated manner. As such, one or more presenters can navigate the scenes and beats of the 3D presentation to deliver the 3D presentation to one or more audience members wearing augmented reality headsets.Type: GrantFiled: July 23, 2021Date of Patent: June 4, 2024Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Darren Alexander Bennett, David J. W. Seymour, Charla M. Pereira, Enrico William Guld, Kin Hang Chu, Julia Faye Taylor-Hell, Jonathon Burnham Cobb, Helen Joan Hem Lam, You-Da Yang, Dean Alan Wadsworth, Andrew Jackson Klein
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Publication number: 20220138344Abstract: In some implementations, a distributed database management system may monitor data operations performed by a plurality of user devices, wherein the data operations are associated with a distributed database. The distributed database management system may detect that a user device is to perform a data operation associated with a data structure of the distributed database. The distributed database management system may determine identification information associated with the user device. The distributed database management system may generate, based on the data operation, evidence information associated with the data operation, wherein the evidence information includes the identification information. The distributed database management system may store the evidence information in an immutable data structure to record that the user device is associated with the data operation.Type: ApplicationFiled: October 30, 2020Publication date: May 5, 2022Inventors: Sunil KRISHNAN, Deepak LALAN, Melvin JAMES TOMY, Amit PUNAMCHAND KAWAD, Sunil GUNASEKARAN, Michael William KLEIN
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Publication number: 20200257954Abstract: A system for determining autonomous actions of a digital persona includes a desire subsystem configured to identify a desire of the digital persona based upon a priority value of the desire determined using a state of the digital persona, and an intent subsystem configured to select a subset of intents with outcomes that are predicted to reduce the priority value of the desire. The system also includes a goal-setting subsystem configured to map the subset of intents to one or more goals with outcomes matching the outcomes of the subset of intents, a planning subsystem configured to determine a set of plan elements for achieving the one or more goals, an action subsystem configured to initiate or perform the set of plan elements, and a sensory subsystem configured to receive feedback and update the state associated with the digital persona.Type: ApplicationFiled: February 11, 2020Publication date: August 13, 2020Applicant: Rival Theory, Inc.Inventors: William Klein, Amanda Solosky, Glenn Huval, Tyler Payne
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Patent number: 10346923Abstract: Systems, apparatus, interfaces, methods, and articles of manufacture that provide for proactive weather awareness and actions.Type: GrantFiled: May 13, 2015Date of Patent: July 9, 2019Assignee: The Travelers Indemnity CompanyInventors: William S. Philbrick, William Klein, Caston S. Brown, Michael J. Hurley
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Publication number: 20160335725Abstract: Systems, apparatus, interfaces, methods, and articles of manufacture that provide for proactive weather awareness and actions.Type: ApplicationFiled: May 13, 2015Publication date: November 17, 2016Inventors: William S. Philbrick, William Klein, Caston S. Brown, Michael J. Hurley
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Publication number: 20160010888Abstract: A heating, ventilation, and/or air conditioning (HVAC) system includes a system controller having a location determination module configured to cause determination and/or reporting of the location of the HVAC system in response to a first run and/or initialization of the HVAC system. The location determination module may determine and/or report location information via global positioning system (GPS) capability, a service provider (SP), customized data provider (CDP), Internet sites, LAN, WAN, 3G, 4G, and/or any other type of network infrastructure to effect reporting of the location of the HVAC system. The system controller may select a climate-based operation parameter value for the HVAC system as a function of a geographic location of the HVAC system.Type: ApplicationFiled: July 10, 2015Publication date: January 14, 2016Inventors: Mark Eldo Groskreutz, Karl Mutchnik, Gregory Brown, Kit William Klein, Stuart Allen Means
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Publication number: 20160003492Abstract: A heating, ventilation, and/or air conditioning (HVAC) system with a thermostat operable to receive, process, and display power consumption information received via a thermistor input of the thermostat. The thermostat receives power consumption information from a measurement device in communication with the thermostat via a wired interface and the thermistor input, wherein the measurement device comprises a clamp portion positionable about an electric conductor, a measurement portion, and a conditioning component.Type: ApplicationFiled: June 30, 2015Publication date: January 7, 2016Inventors: Kit William Klein, Karl Mutchnik, Robert Frederick Schull
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Publication number: 20150161852Abstract: In a gaming system, a first player and one or more second player(s) contribute respective player reels. At least one game outcome is determined from an array of symbols randomly generated from the combination of the player reels. The at least one game outcome is shared by all players and used to determine awards for all players. The first player may subsequently join one or more third player(s) to determine new game outcomes from a new combination of player reels. In another gaming system, players select a combination of player reels from a pool of player reels to compete against each other. At least one game outcome is determined for each player from an array of symbols randomly generated from the player's selected subset of player reels. The players are ranked according to the game outcomes for the players, and awards are determined for the players according to the ranking.Type: ApplicationFiled: December 5, 2013Publication date: June 11, 2015Applicant: WMS Gaming Inc.Inventors: Richard B. Robbins, Andrew C. Guinn, William Klein, Daniel P. Louie, Aaron John Schurman, Bryan Vandaele, Jamie W. Vann
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Patent number: 8383113Abstract: The present invention relates to antibodies that differentially recognize multi-dimensional conformations of A?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid ? 1-42.Type: GrantFiled: February 8, 2012Date of Patent: February 26, 2013Assignees: Northwestern University, Merck Sharp & Dohme Corp.Inventors: Paul Acton, Zhiqiang An, Andrew J. Bett, Robert Breese, Lei Chang, Elizabeth Chen Dodson, Gene Kinney, William Klein, Mary P. Lambert, Xiaoping Liang, Paul Shughrue, William R. Strohl, Kristen Viola
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Publication number: 20120171224Abstract: The present invention relates to antibodies that differentially recognize multi-dimensional conformations of A?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid ? 1-42.Type: ApplicationFiled: February 8, 2012Publication date: July 5, 2012Inventors: Paul Acton, Zhiqiang An, Andrew J. Bett, Robert Breese, Lei Chang, Elizabeth Chen Dodson, Gene Kinney, William Klein, Mary P. Lambert, Xiaoping Liang, Paul Shughrue, William R. Strohl, Kristen Viola
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Publication number: 20100272714Abstract: The present invention relates to antibodies that differentially recognize multi-dimensional conformations of A?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLs, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid ? 1-42.Type: ApplicationFiled: July 1, 2010Publication date: October 28, 2010Inventors: Paul Acton, Zhiqiang An, Andrew J. Bett, Robert Breese, Lei Chang, Elizabeth Chen Dodson, Gene Kinney, William Klein, Mary P. Lambert, Xiaoping Liang, Paul Shughrue, William R. Strohl, Kristen Viola
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Patent number: 7780963Abstract: The present invention relates to antibodies that differentially recognize multi-dimensional conformations of A?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid ?1-42.Type: GrantFiled: October 21, 2005Date of Patent: August 24, 2010Assignees: Merck & Co., Inc., Northwestern UniversityInventors: Paul Acton, Zhiqiang An, Andrew J. Bett, Robert Breese, Lei Chang, Elizabeth Chen Dodson, Gene Kinney, William Klein, Mary P. Lambert, Xiaoping Liang, Paul Shughrue, William R. Strohl, Kirsten Viola
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Publication number: 20070264669Abstract: The present invention relates to methods for enhancing the cellular uptake and clearance of soluble oligomeric A? peptide assemblies from the environment surrounding both neuronal and non-neuronal cells. Oligomeric A? peptide assembly uptake and clearance is achieved via an agent that enhances insulin receptor signaling. Such ADDL uptake enhancers represent effective anti-ADDL therapeutics for use in the therapeutic treatment and/or prophylactic treatment of diseases including Alzheimer's disease, Down's syndrome, and the like, in which compromised nerve cell function is linked to the formation and/or the activity of soluble oligomeric A? peptide assemblies, also known as ADDLs, and ADDL-related assemblies.Type: ApplicationFiled: May 11, 2007Publication date: November 15, 2007Inventors: Wei-Qin Zhao, Grant Krafft, William Klein
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Publication number: 20070218499Abstract: Disclosed herein are antibodies that bind with high specificity to soluble oligomers of amyloid ? (Abeta) and methods of employing those antibodies. The antibodies are able to distinguish between Alzheimer's Disease (AD) and control human brain extracts. The antibodies identify endogenous Abeta oligomers in AD brain slices and also bind to Abeta oligomers on cultured hippocampal cells. The antibodies neutralize endogenous Abeta oligomers and Abeta oligomers produced in solution.Type: ApplicationFiled: July 5, 2005Publication date: September 20, 2007Inventors: Mary Lambert, Pauline Velasco, Lei Chang, Kirsten Viola, Sara Fernandez, Pascale Lacor, Daliya Khuon, Yuesong Gong, William Klein, Grant Krafft
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Publication number: 20070213512Abstract: The present invention provides amyloid ? peptide assemblies composed of at least three amyloid ? peptide subunits, wherein at least one of the amyloid ? peptide subunits is an amyloid ? peptide analog. The invention further relates to metal complexes of amyloid ? peptide assemblies and the use of amyloid ? peptide assemblies as vaccines and in the identification of agents that modulate assembly of the amyloid ? peptide subunits.Type: ApplicationFiled: March 15, 2007Publication date: September 13, 2007Inventors: Grant Krafft, William Klein, Kirsten Viola, Mary Lambert, Todd Pray, Ray Lowe
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Publication number: 20070173355Abstract: Embodiments provide mechanisms and methods for measuring shooting performance in multiplayer environments. These mechanisms and methods include automatic synchronization that enables sensors associated with multiple players to interact with one or more control consoles in a common playing area free of interference. The ability to associate sensors to interact with one or more control consoles in a common playing area free of interference make it possible for coaches and players to measure levels of play, build teamwork among multiple players, improve and maintain skills, select players to meet game situations and team requirements, make decisions on player roles, and use playing environment space more efficiently.Type: ApplicationFiled: November 17, 2006Publication date: July 26, 2007Inventor: William Klein
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Publication number: 20070048312Abstract: The invention herein comprises antibodies that bind to amyloid beta-derived diffusible ligands (ADDLs). ADDLs comprise amyloid ? protein assembled into soluble, globular, non-fibrillar, oligomeric structures capable of activating specific cellular processes.Type: ApplicationFiled: July 31, 2006Publication date: March 1, 2007Inventors: William Klein, Grant Krafft, Mary Lambert, Kirsten Viola, Brett Chromy, Lei Chang
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Publication number: 20060228349Abstract: The present invention relates to antibodies that differentially recognize multi-dimensional conformations of A?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid ?1-42.Type: ApplicationFiled: October 21, 2005Publication date: October 12, 2006Inventors: Paul Acton, Zhiqiang An, Andrew Bett, Robert Breese, Lei Chang, Elizabeth Dodson, Gene Kinney, William Klein, Mary Lambert, Xiaoping Liang, Paul Shughrue, William Strohl, Kirsten Viola
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Publication number: 20060226592Abstract: A media feeding apparatus includes a side wall, the side wall having a first side surface and an opposite side surface. A sheet picking mechanism has a pick arm and a pick roller. The pick arm is configured to mount the pick roller. The pick arm has a pivot axis substantially perpendicular to the side wall. A restraint is mounted to the pick arm, wherein at least the first side surface of the side wall is in close proximity to the restraint.Type: ApplicationFiled: March 29, 2005Publication date: October 12, 2006Inventor: William Klein
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Publication number: 20060178302Abstract: The invention provides amyloid beta-derived dementing ligands (ADDLs) that comprise amyloid ? protein assembled into globular non-fibrillar oligomeric structures capable of activating specific cellular processes. The invention also provides methods for assaying the formation, presence, receptor protein binding and cellular activity of ADDLs, as well as compounds that block the formation or activity of ADDLs, and methods of identifying such compounds. The invention further provides methods of using ADDLs, and modulating ADDL formation and/or activity, inter alia in the treatment of learning and/or memory disorders.Type: ApplicationFiled: April 6, 2005Publication date: August 10, 2006Inventors: Grant Krafft, William Klein, Brett Chromy, Mary Lambert, Caleb Finch, Todd Morgan, Pat Wals, Irina Rozovsky, Ann Barlow