Abstract: The present invention provides a method for detecting the presence of a predetermined infectious agent in a human or animal subject comprising obtaining a preselected portion of a whole blood sample containing at least one intact blood cell from the subject and detecting the presence of a nucleic acid from the predetermined infectious agent in the intact blood cell by nucleic acid hybridization. The preselected portion of the blood sample can include any portion which contains at least one intact blood cell, for example a peripheral blood smear or cytospin buffy coat preparation. The intact blood cell can be any blood cell including, but not limited to white blood cells and red blood cells. In one embodiment, the blood cell is a lymphocyte.

Abstract: The present invention relates to biologically-active copolymers and to compounds that can be safely used to cause the thymus of an animal or human to increase in size, thereby replenishing the T-lymphocyte population. When injected into an animal or human with an antigen, certain of the biologically-active copolymers cause immunosuppression to the antigen.When injected into poultry, certain of the biologically-active copolymers modulate immune responsiveness. The biologically active copolymers are also useful as growth promoters for animals. Compounds within the biologically-active copolymers of the present invention are effective tumoricidal agents. At low concentration, certain of the biologically-active copolymers can cause dedifferentiated cells to differentiate.The biologically-active copolymer of the present invention is a safe and non-toxic formulation that can effectively be administered to animals or humans.

Abstract: In accordance with the present invention, a method is provided for treating poultry for coccidiosis. The method comprises administering an effective amount of a biologically-active copolymer on the poultry with coccidiosis, the octablock copolymer being selected from the group consisting of an octablock copolymer having the following formula: ##STR1## and an octablock copolymer having the following formula: ##STR2## wherein: the mean aggregate molecular weight of the portion of the octablock copolymer represented by the polyoxypropylene is between approximately 5000 and 7000 daltons;a is a number such that the portion represented by polyoxyethylene constitutes between approximately 10% to 40% of the compound by weight; andb is a number such that the polyoxypropylene portion of the total molecular weight of the octablock copolymer constitutes between approximately 50% and 90% of the compound by weight.

Abstract: The present invention relates to biologically-active copolymers and to compounds that can be safely used to cause the thymus of an animal or human to increase in size, thereby replenishing the T-lymphocyte population. When injected into an animal or human with an antigen, certain of the biologically-active copolymers cause immunosuppression to the antigen.When injected into poultry, certain of the biologically-active copolymers modulate immune responsiveness. The biologically active copolymers are also useful as growth promoters for animals. Compounds within the biologically-active copolymers of the present invention are effective tumoricidal agents. At low concentration, certain of the biologically-active copolymers can cause dedifferentiated cells to differentiate.The biologically-active copolymer of the present invention is a safe and non-toxic formulation that can effectively be administered to animals or humans.

Abstract: A method of immunizing chickens in which a vaccine preparation containing both an inactivated mycoplasma and an adjuvant which stimulates the mucosal immune system is administered to chickens intracoelomically. Preferably, the vaccine preparation is subsequently administered to the chickens intranasally, intrabursally or intratracheally. The preferred adjuvant is iota carrageenan.

Abstract: The present invention relates to an immunotherapeutic agent that is effective in treating a wide variety of ongoing viral infections in animals and man. The present invention is a preparation of modified mycobacterial cell walls that is capable of stimulating the immune system of an animal or man in such a way as to cause the body to neutralize, abort or eliminate an virus infection.