Patents by Inventor William M. Gallatin

William M. Gallatin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calcineurin inhibitory compounds and anchoring protein
    Patent number: 5807693
    Abstract: The present invention provides compositions and methods useful for isolating calcineurin as well as inhibiting calcineurin activity. The compositions are peptides that contain regions that are homologous to calcineurin-binding regions of AKAP 79. Also provided are methods for determining if a cell contains a calcineurin-binding and PKA-binding anchoring protein that are useful for identifying additional proteins that bind both calcineurin and PKA.
    Type: Grant
    Filed: November 23, 1994
    Date of Patent: September 15, 1998
    Assignees: ICOS Corporation, The State of Oregon, acting by and through the Oregon State Board of Higher Education, and on Behalf of the Oregon Health Science University
    Inventors: John D. Scott, Vincent M. Coghlan, Monique L. Howard, William M. Gallatin
  • Calcineurin inhibitory compounds and anchoring protein
    Patent number: 5629163
    Abstract: The present invention provides compositions and methods useful for isolating calcineurin as well as inhibiting calcineurin activity. The compositions are peptides that contain regions that are homologous to calcineurin-binding regions of AKAP 79. Also provided are methods for determining if a cell contains a calcineurin-binding and PKA-binding anchoring protein that are useful for identifying additional proteins that bind both calcineurin and PKA.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: May 13, 1997
    Assignees: ICOS Corporation, The State of Oregon acting by and through the Oregon State Board of Higher Education and on behalf of Oregon Health Sciences University
    Inventors: John D. Scott, Vincent M. Coghlan, Monique L. Howard, William M. Gallatin
  • Human .beta..sub.2 integrin .alpha. subunit
    Patent number: 5437958
    Abstract: DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d.
    Type: Grant
    Filed: December 23, 1993
    Date of Patent: August 1, 1995
    Assignee: ICOS Corporation
    Inventors: William M. Gallatin, Monica Van der Vieren
  • IL-4 and TNF induce mAb 6G10-recognized expression on bone marrow stromal cells
    Patent number: 5206345
    Abstract: An improved method of screening a cell line for the production of a binding partner that binds with a cell-surface molecule, by contacting the binding partner with IL4-activated and nonactivated human bone marrow stromal cells, and selecting binding partners that bind to the IL4-activated human bone marrow stromal cells but not to the nonactivated human bone marrow stromal cells. The selected binding partners may thereafter be tested for the ability to block CD34.sup.+ bone marrow cell binding to IL4-activated human bone marrow stromal cells. The binding partners are preferably also characterized by binding to human VCAM-1. A representative embodiment is mAb 6G10 produced by hybridoma ATTC No. HB 10519.
    Type: Grant
    Filed: August 2, 1990
    Date of Patent: April 27, 1993
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Boris Masinovsky, William M. Gallatin, Paul J. Simmons