Patents by Inventor William P. Donovan
William P. Donovan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10913939Abstract: The disclosure provides nucleic acid constructs encoding novel chimeric peptides that are useful for nuclear and chloroplast expression of active nitrogenase components including dinitrogenase reductase and dinitrogenase, in plant cells. The disclosure thus provides nucleic acid constructs encoding the chimeric proteins, as well as plant expression constructs comprising the same for expression and/or targeting to the nucleus, plastids, or mitochondria of plant cells. The disclosure also provides methods of use for the novel chimeric peptides that function to provide active dinitrogenase reductase, dinitrogenase, and thus nitrogenase, expressed in plant cells, and plants comprising such nucleic acid constructs.Type: GrantFiled: March 24, 2016Date of Patent: February 9, 2021Assignee: Monsanto Technology LLCInventors: William P. Donovan, Natalia Ivleva, Jeffrey M. Staub
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Patent number: 10570414Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.Type: GrantFiled: November 10, 2016Date of Patent: February 25, 2020Assignee: Monsanto Technology LLCInventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
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Publication number: 20170067076Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.Type: ApplicationFiled: November 10, 2016Publication date: March 9, 2017Applicant: Monsanto Technology LLCInventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
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Patent number: 9528121Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.Type: GrantFiled: January 22, 2013Date of Patent: December 27, 2016Assignee: Monsanto Technology LLCInventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
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Publication number: 20160304842Abstract: The disclosure provides nucleic acid constructs encoding novel chimeric peptides that are useful for nuclear and chloroplast expression of active nitrogenase components including dinitrogenase reductase and dinitrogenase, in plant cells. The disclosure thus provides nucleic acid constructs encoding the chimeric proteins, as well as plant expression constructs comprising the same for expression and/or targeting to the nucleus, plastids, or mitochondria of plant cells. The disclosure also provides methods of use for the novel chimeric peptides that function to provide active dinitrogenase reductase, dinitrogenase, and thus nitrogenase, expressed in plant cells, and plants comprising such nucleic acid constructs.Type: ApplicationFiled: March 24, 2016Publication date: October 20, 2016Inventors: William P. Donovan, Natalia lvleva, Jeffrey M. Staub
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Patent number: 8796026Abstract: The present invention relates to the isolation and characterization of nucleotide sequences encoding novel insecticidal proteins secreted into the extracellular space from Bacillus thuringiensis and related strains. The proteins are isolated from culture supernatants of Bacillus thuringiensis and related strains and display insecticidal activity against coleopteran insects including Colorado potato beetle (Lymantria dispar) and Southern Corn Rootworm (Diabrotica undecempunctata). Insecticidal proteins encoded by nucleotide sequences that hybridize to the isolated and characterized nucleotide sequences are disclosed. Also disclosed are methods of making and using transgenic cells and plants comprising the novel nucleotide sequence of the invention.Type: GrantFiled: July 6, 2004Date of Patent: August 5, 2014Assignee: Monsanto Technology LLCInventors: James A. Baum, Judith C. Donovan, William P. Donovan, James T. Engleman, Karina Krasomil-Osterfeld, John W. Pitkin, James K. Roberts
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Patent number: 8410334Abstract: This invention provides a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest, recombinant DNA constructs for expression of at least one invertebrate miRNA in planta and methods of use thereof, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.Type: GrantFiled: February 19, 2008Date of Patent: April 2, 2013Assignee: Monsanto Technology LLCInventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
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Patent number: 7772369Abstract: Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed host cells, and transgenic plants that contain nucleic acid segments that encode the disclosed ?-endotoxin polypeptides. Also disclosed are methods of identifying related polypeptides and polynucleotides, methods of making and using transgenic cells comprising these polynucleotide sequences, as well as methods for controlling an insect population, such as Colorado potato beetle, southern corn rootworm and western corn rootworm, and for conferring to a plant resistance to a target insect species.Type: GrantFiled: October 23, 2008Date of Patent: August 10, 2010Assignee: Monsanto Technology LLCInventors: Mark J. Rupar, William P. Donovan, Chih-Rei Chu, Elizabeth Pease, Yuping Tan, Annette C. Slaney, Thomas M. Malvar, James A. Baum
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Patent number: 7662940Abstract: Nucleic acid sequences and insecticidal proteins encoded from these sequences are provided. Insecticidal proteins encoded by large operons situated within the primary sequence of large extrachromosomal plasmids present in Bacillus thuringiensis are disclosed. Methods for making transgenic plants resistant to insect infestation as a result of expression of one or more of these proteins is disclosed. Bacillus thuringiensis strains exhibiting broad host range insecticidal specificity are also disclosed.Type: GrantFiled: August 1, 2005Date of Patent: February 16, 2010Assignee: Monsanto Technology LLCInventors: James A. Baum, William P. Donovan, Brian B. Hauge, Thomas J. LaRosa
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Publication number: 20090270327Abstract: Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against lepidopteran insects. Also disclosed are novel B. thuringiensis genes and their encoded crystal proteins, as well as methods of making and using transgenic cells comprising the novel nucleic acid sequences of the invention.Type: ApplicationFiled: May 18, 2009Publication date: October 29, 2009Inventors: James A. Baum, Chih-Rei Chu, William P. Donovan, Amy J. Gilmer, Mark J. Rupar
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Patent number: 7572587Abstract: Disclosed is a novel ?-endotoxin, designated CryET29, that exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea (Ctenocephalides felis), as well as against coleopteran insects, including the southern corn rootworm (Diabrotica undecimpunctata), western corn rootworm (D. virgifera), Colorado potato beetle (Leptinotarsa decemlineata), Japanese beetle (Popillia japonica), and red flour beetle (Tribolium castaneum). Also disclosed are nucleic acid segments encoding CryET29, recombinant vectors, host cells, and transgenic plants comprising a cryET29 DNA segment. Methods for making and using the disclosed protein and nucleic acid segments are disclosed as well as assays and diagnostic kits for detecting cryET29 and CryET29 sequences in vivo and in vitro.Type: GrantFiled: March 1, 2007Date of Patent: August 11, 2009Assignee: Monsanto Technology LLCInventors: Mark J. Rupar, William P. Donovan, Yuping Tan, Annette C. Slaney
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Patent number: 7534939Abstract: Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against lepidopteran insects. Also disclosed are novel B. thuringiensis genes and their encoded crystal proteins, as well as methods of making and using transgenic cells comprising the novel nucleic acid sequences of the invention.Type: GrantFiled: July 17, 2006Date of Patent: May 19, 2009Assignee: Monsanto Technology LLCInventors: James A. Baum, Chih-Rei Chu, William P. Donovan, Amy J. Gilmer, Mark J. Rupar
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Publication number: 20090098099Abstract: Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against lepidopteran insects. Also disclosed are novel B. thuringiensis genes and their encoded crystal proteins, as well as methods of making and using transgenic cells comprising the novel nucleic acid sequences of the invention.Type: ApplicationFiled: July 17, 2006Publication date: April 16, 2009Inventors: James A. Baum, Chih-Rei Chu, William P. Donovan, Amy J. Gilmer, Mark J. Rupar
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Publication number: 20090094714Abstract: Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed host cells, and transgenic plants that contain nucleic acid segments that encode the disclosed ?-endotoxin polypeptides. Also disclosed are methods of identifying related polypeptides and polynucleotides, methods of making and using transgenic cells comprising these polynucleotide sequences, as well as methods for controlling an insect population, such as Colorado potato beetle, southern corn rootworm and western corn rootworm, and for conferring to a plant resistance to a target insect species.Type: ApplicationFiled: October 23, 2008Publication date: April 9, 2009Inventors: Mark J. Rupar, William P. Donovan, Chih-Rei Chu, Elizabeth Pease, Yuping Tan, Annette C. Slaney, Thomas M. Malvar, James A. Baum
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Patent number: 7504229Abstract: Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against coleopteran insects including red flour beetle larvae (Tribolium castaneum) and Japanese beetle larvae (Popillia japonica). Also disclosed are novel B. thuringiensis crystal toxin genes, designated cryET33 and cryET34, which encode the colepteran-toxic crystal proteins, CryET33 (29-kDa) crystal protein, and the cryET34 gene encodes the 14-kDa CryET34 crystal protein. The CryET33 and CryET34 crystal proteins are toxic to red flour beetle larvae and Japanese beetle larvae. Also disclosed are methods of making and using transgenic cells comprising the novel nucleic acid sequences of the invention.Type: GrantFiled: September 20, 2005Date of Patent: March 17, 2009Assignee: Monsanto Technology LLCInventors: William P. Donovan, Judith C. Donovan, Annette C. Slaney
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Publication number: 20080274502Abstract: Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against coleopteran insects including red flour beetle larvae (Tribolium castaneum) and Japanese beetle larvae (Popillia japonica). Also disclosed are novel B. thuringiensis crystal toxin genes, designated cryET33 and cryET34, which encode the colepteran-toxic crystal proteins, CryET33 (29-kDa) crystal protein, and the cryET34 gene encodes the 14-kDa CryET34 crystal protein. The CryET33 and CryET34 crystal proteins are toxic to red flour beetle larvae and Japanese beetle larvae. Also disclosed are methods of making and using transgenic cells comprising the novel nucleic acid sequences of the invention.Type: ApplicationFiled: June 9, 2008Publication date: November 6, 2008Inventors: William P. Donovan, Judith C. Donovan, Annette C. Slaney
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Patent number: 7442540Abstract: Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed host cells, and transgenic plants that contain nucleic acid segments that encode the disclosed ?-endotoxin polypeptides. Also disclosed are methods of identifying related polypeptides and polynucleotides, methods of making and using transgenic cells comprising these polynucleotide sequences, as well as methods for controlling an insect population, such as Colorado potato beetle, southern corn rootworm and western corn rootworm, and for conferring to a plant resistance to a target insect species.Type: GrantFiled: July 12, 2006Date of Patent: October 28, 2008Assignee: Monsanto Technology LLCInventors: Mark J. Rupar, William P. Donovan, Chih-Rei Chu, Elizabeth Pease, Yuping Tan, Annette C. Slaney, Thomas M. Malvar, James A. Baum
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Publication number: 20080229449Abstract: Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against lepidopteran insects. Also disclosed are novel B. thuringiensis genes and their encoded crystal proteins, as well as methods of making and using transgenic cells comprising the novel nucleic acid sequences of the invention.Type: ApplicationFiled: February 12, 2008Publication date: September 18, 2008Inventors: James A. Baum, Chih-Rei Chu, William P. Donovan, Amy J. Gilmer, Mark J. Rupar
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Publication number: 20080201801Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.Type: ApplicationFiled: February 19, 2008Publication date: August 21, 2008Inventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
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Patent number: 7385107Abstract: Disclosed are transgenic plants, seeds, and progeny from such plants comprising novel nucleic acid sequences encoding both CryET33 and CryET34 crystal proteins. The novel nucleic acid sequences comprise SEQ ID NO:11. CryET33 and CryET34 crystal proteins comprise SEQ ID NO:3 and SEQ ID NO:4 and exhibit insecticidal activity against coleopteran insects including red flour beetle larvae (Tribolium castaneum) and Japanese beetle larvae (Popillia japonica).Type: GrantFiled: June 4, 2002Date of Patent: June 10, 2008Assignee: Monsanto Technologies LLCInventors: William P. Donovan, Judith C. Donovan, Annette C. Slaney