Patents by Inventor William Polvino

William Polvino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240024303
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Application
    Filed: June 22, 2023
    Publication date: January 25, 2024
    Inventors: William MANN, John FRIEND, William POLVINO, Suzan ALLEN, Ming LU, Elizabeth DUUS, Ruben Giorgino, Enrico Baroni
  • Patent number: 11723902
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: August 15, 2023
    Assignee: Helsinn Healthcare SA
    Inventors: William Mann, John Friend, William Polvino, Suzan Allen, Ming Lu, Elizabeth Duus, Ruben Giorgino, Enrico Baroni
  • Publication number: 20210093627
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Application
    Filed: December 11, 2020
    Publication date: April 1, 2021
    Inventors: William MANN, John FRIEND, William POLVINO, Suzan ALLEN, Ming LU, Elizabeth DUUS, Ruben Giorgino, Enrico Baroni
  • Patent number: 10894041
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: January 19, 2021
    Assignee: Helsinn Healthcare SA
    Inventors: William Mann, John Friend, William Polvino, Suzan Allen, Ming Lu, Elizabeth Duus, Ruben Giorgino, Enrico Baroni
  • Publication number: 20190175574
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Application
    Filed: February 14, 2019
    Publication date: June 13, 2019
    Inventors: William MANN, John FRIEND, William POLVINO, Suzan ALLEN, Ming LU, Elizabeth DUUS, Ruben Giorgino, Enrico Baroni
  • Patent number: 10278964
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: May 7, 2019
    Assignee: Helsinn Healthcare SA
    Inventors: William Mann, John Friend, William Polvino, Suzan Allen, Ming Lu, Elizabeth Duus, Ruben Giorgino, Enrico Baroni
  • Publication number: 20170296526
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Application
    Filed: May 9, 2017
    Publication date: October 19, 2017
    Inventors: William MANN, John FRIEND, William POLVINO, Suzan ALLEN, Ming LU, Elizabeth DUUS, Ruben Giorgino, Enrico Baroni
  • Patent number: 9675600
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: June 13, 2017
    Assignee: HELSINN HEALTHCARE SA
    Inventors: William Mann, John Friend, William Polvino, Suzan Allen, Ming Lu, Elizabeth Duus, Ruben Giorgino, Enrico Baroni
  • Publication number: 20160067236
    Abstract: Methods of treating cancer related conditions using anamorelin are described.
    Type: Application
    Filed: August 28, 2015
    Publication date: March 10, 2016
    Inventors: William MANN, John FRIEND, William POLVINO, Suzan ALLEN, Ming LU, Elizabeth DUUS
  • Publication number: 20070191283
    Abstract: The present invention relates to a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders or diseases) of the gastrointestinal system. The method comprises administering to a subject in need thereof a therapeutically effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof. The growth hormone secretagogue can be co-administered with a laxative, a H2 receptor antagonist, a serotonin 5-HT4 agonist, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Application
    Filed: August 12, 2005
    Publication date: August 16, 2007
    Inventor: William Polvino
  • Publication number: 20060078494
    Abstract: The present invention relates to a method of treating cancer in a subject. The method comprises administering to a subject suffering from cancer a therapeutically effective amount of a 24-hydroxylase inhibitor in combination with a second amount of a suitable cancer therapeutic. The 24-hydroxylase inhibitor can be coadministered with a chemotherapeutic agent, such an antitumor antibiotic (e.g., mitoxantrone or bleomycin), an alkylating agent (e.g., estramustine or melphalan), a plant alkaloid (e.g., taxenes such as paclitaxel or docetaxel or vinca alkaloids such as vincristine or vinblastine) or a combination thereof. In additional therapy, the 24-hydroxylase inhibitor can be coadministered as an adjuvant to radiation therapy, such as an external beam irradiation or a radioisotope therapy, such as radiopharmaceutical therapy. Further, the 24-hydroxylase inhibitor can be coadministered as part of a combination therapy that includes hormonal ablation.
    Type: Application
    Filed: September 23, 2005
    Publication date: April 13, 2006
    Inventor: William Polvino
  • Publication number: 20060074109
    Abstract: The present invention relates to a method of treating cancer in a subject. The method comprises administering to a subject suffering from cancer a therapeutically effective amount of a 24-hydroxylase inhibitor. In certain embodiments, the 24-hydroxylase inhibitor can be coadministered with calcitriol.
    Type: Application
    Filed: September 26, 2005
    Publication date: April 6, 2006
    Inventors: William Polvino, Timo Ylikomi, Yan-Ru Lou, Merja Ahonen, Pentti Tuohimaa, Susanna Miettinen
  • Publication number: 20050261201
    Abstract: The present invention relates to a method of reducing C-reactive protein in a subject in need of treatment thereof, wherein the subject is at risk of having or the subject has already had a vascular event or suffering from an inflammatory disease or disorder. In one embodiment, the vascular event is a cardiovascular event (e.g., myocardial infarction). In another embodiment, the vascular event is a cerebrovascular event (e.g., stroke (such as transient ischemic attacks (TIAs)). In yet another embodiment the vascular event is a peripheral vascular event (e.g., intermittent claudication). The method comprises administering a therapeutically effective amount of at least one growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof.
    Type: Application
    Filed: March 30, 2005
    Publication date: November 24, 2005
    Applicant: Rejuvenon Corporation
    Inventors: William Polvino, David Carpi, Roy Smith