Patents by Inventor William R. Mann

William R. Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating emesis using growth hormone secretagogues
    Patent number: 8394833
    Abstract: The present invention relates to methods of treating emesis by administering to the subject an effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: March 12, 2013
    Assignee: Helsinn Therapeutics (U.S.), Inc.
    Inventors: William R. Mann, William J. Polvino
  • Methods of treating emesis using growth hormone secretagogues
    Patent number: 8288427
    Abstract: A method of treating emesis with growth hormone secretagogues, particularly ipamorelin.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: October 16, 2012
    Assignee: Helsinn Therapeutics (U.S.), Inc.
    Inventors: William R. Mann, William J. Polvino
  • METHODS OF TREATING EMESIS USING GROWTH HORMONE SECRETAGOGUES
    Publication number: 20120232113
    Abstract: The present invention relates to methods of treating or preventing emesis and improving a subject's ASAS score by administering to the subject an effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof.
    Type: Application
    Filed: May 21, 2012
    Publication date: September 13, 2012
    Applicant: HELSINN THERAPEUTICS (U.S.), INC.
    Inventors: William R. Mann, William J. Polvino
  • Method of stimulating the motility of the gastrointestinal system using ipamorelin
    Publication number: 20120010157
    Abstract: The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2 receptor antagonist, a serotonin receptor agonist, pure or mixed, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Application
    Filed: September 16, 2011
    Publication date: January 12, 2012
    Applicant: HELSINN THERAPEUTICS (U.S.), INC.
    Inventors: William J. Polvino, Richard Nelson, William R. Mann
  • Method of stimulating the motility of the gastrointestinal system using ipamorelin
    Patent number: 8039456
    Abstract: The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2 receptor antagonist, a serotonin receptor agonist, pure or mixed, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: October 18, 2011
    Assignee: Helsinn Therapeutics (U.S.), Inc.
    Inventors: William J. Polvino, Richard Nelson, William R. Mann
  • Method of stimulating the motility of the gastrointestinal system using ipamorelin
    Publication number: 20090143310
    Abstract: The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2 receptor antagonist, a serotonin receptor agonist, pure or mixed, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Application
    Filed: November 26, 2008
    Publication date: June 4, 2009
    Applicant: Sapphire Therapeutics
    Inventors: William J. Polvino, Richard Nelson, William R. Mann
  • Methods of treating emesis using growth hormone secretagogues
    Publication number: 20080300194
    Abstract: The present invention relates to methods of treating or preventing emesis and improving a subject's ASAS score by administering to the subject an effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof.
    Type: Application
    Filed: April 10, 2008
    Publication date: December 4, 2008
    Applicant: Sapphire Therapeutics, Inc.
    Inventors: William R. Mann, William J. Polvino