Abstract: A biopsy device or hand tool for taking a sample of body tissue. The hand tool includes a stylus for forming an opening in relatively firm tissue such as the bone cortex, and a cannula formed by a pair of tubes for cutting and capturing a sample of a less firm tissue, such as bone marrow. The stylus is used initially when in the cannula and is withdrawn from the cannula after it has carved an opening in the bone cortex larger than the diameter of the outside diameter of the cannula. The cannula includes an outer elongate tube having a distal end portion with a cutting edge and opening and further includes an inner elongate tube having a distal end portion which also includes a cutting edge and opening. The tubes are rotatable relative to each other, an action which cuts off or at least partially cuts off the tissue connection which still exists to base tissue.