Patents by Inventor William Shell

William Shell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7601369
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: October 13, 2009
    Assignee: Targeted Medical Pharma Inc.
    Inventors: William Shell, Elizabeth Charuvastra
  • Patent number: 7595067
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: September 29, 2009
    Assignee: Targeted Medical Pharma Inc.
    Inventors: William Shell, Elizabeth Charuvastra
  • Patent number: 7585523
    Abstract: A method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The compositions for medical foods are designed to improve cognitive function, induced sleep, improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as cocoa. The method uses physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: September 8, 2009
    Assignee: Targeted Medical Pharma
    Inventors: William Shell, Elizabeth Charuvastra
  • Patent number: 7582315
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: September 1, 2009
    Assignee: Targeted Medical Pharma, Inc.
    Inventors: William Shell, Elizabeth Charuvastra
  • Publication number: 20070166408
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Application
    Filed: March 5, 2007
    Publication date: July 19, 2007
    Inventors: William Shell, Elizabeth Charuvastra
  • Publication number: 20070160690
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Application
    Filed: March 5, 2007
    Publication date: July 12, 2007
    Inventors: William Shell, Elizabeth Charuvastra
  • Publication number: 20070160650
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.
    Type: Application
    Filed: March 5, 2007
    Publication date: July 12, 2007
    Inventors: William Shell, Elizabeth Charuvastra
  • Publication number: 20060159726
    Abstract: The methods and compositions for potentiating pharmaceuticals with amino acid based medical foods provides improved cognitive function; induced and maintained sleep; reduced pain, inflammation, blood pressure, anxiety, asthma, duration of viral infection, insulin resistance, and appetite; and treated depression. The amino acid based medical foods, co-packed with at least one selected pharmaceutical, potentiate the pharmaceutical by enhancing the production of neurotransmitters through the oral administration of neurotransmitter precursors, along with natural plant and animal substances that stimulate uptake of the neurotransmitter precursors, cause release of neurotransmitters, cause disinhibition of the neuronal brake, and activate adenylate cyclase in order to avoid tachyphylaxis and prevent pharmacologic tolerance.
    Type: Application
    Filed: March 22, 2006
    Publication date: July 20, 2006
    Inventors: William Shell, Elizabeth Charuvastra
  • Publication number: 20050010123
    Abstract: A quantitative method for measuring a cardiac function interval is described as well as its application to differentiating among populations of patients. Once such populations are characterized, said method can be used as a diagnostic test for individual patients when their measured data is compared against the composite data collected by the methods herein. Beat-to-beat electrocardiographic interval data is collected over an extended period of time, such beat-to-beat data being obtained from more than one subject, the beat-to-beat interval data from each subject is then used to create a composite histogram. A series of bins representing a histogram, each of which has a value range, is defined for each subject. The collected data are organized into the bins in accordance with the value of the data and the value range of the bin, thereby creating a set of bins of each interval for each subject. A composite histogram from the set of patients is constructed by summing the data from each bin.
    Type: Application
    Filed: July 9, 2003
    Publication date: January 13, 2005
    Inventors: Elizabeth Charuvastra, William Shell, Joan Horvath
  • Publication number: 20040043054
    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca.
    Type: Application
    Filed: August 27, 2002
    Publication date: March 4, 2004
    Inventors: William Shell, Elizabeth Charuvastra
  • Patent number: 6577894
    Abstract: A quantitative method and apparatus for measuring a cardiac function interval. Beat-to-beat data representative of a cardiac interval is collected over an extended period of time. A series of bins, each of which has a defined value range, is defined. The collected data is organized into the bins in accordance with the value of the data and the value range of the bin. The percentage of data in each bin may be calculated based upon the quantity of data in each bin.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: June 10, 2003
    Assignee: Beverly Glen Medical Systems, LLC
    Inventors: Timothy Callahan, William Shell
  • Publication number: 20020095095
    Abstract: A quantitative method and apparatus for measuring a cardiac function interval. Beat-to-beat data representative of a cardiac interval is collected over an extended period of time. A series of bins, each of which has a defined value range, is defined. The collected data is organized into the bins in accordance with the value of the data and the value range of the bin. The percentage of data in each bin may be calculated based upon the quantity of data in each bin.
    Type: Application
    Filed: October 19, 2001
    Publication date: July 18, 2002
    Inventors: Timothy Callahan, William Shell
  • Patent number: 6324423
    Abstract: A quantitative method and apparatus for measuring a cardiac function interval. Beat-to-beat data representative of a cardiac interval is collected over an extended period of time. A series of bins, each of which has a defined value range, is defined. The collected data is organized into the bins in accordance with the value of the data and the value range of the bin. The percentage of data in each bin may be calculated based upon the quantity of data in each bin.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: November 27, 2001
    Inventors: Timothy Callahan, William Shell
  • Patent number: 4680171
    Abstract: An inexpensive and easy to use method of visualizing an arterial circulation using biodegradable microspheres dyed with an X-ray absorbent material, which enables the diagnosis of pulmonary embolism, is provided. The microspheres may be comprised of a variety of materials, including human albumin, and may be dyed with a number of X-ray absorbent materials, including hypaque-sodium and potassium iodide. The microspheres are injected into bloodstream at a particular location such that they travel through the desired arterial circulation, where they become lodged. Upon exposure of the arterial circulation to X-rays, blood vessels therein containing the microspheres will absorb the X-rays, causing them to show on a developed X-ray in contrast to other blood vessels and body tissue which do not contain the microspheres that transmit the X-rays.
    Type: Grant
    Filed: March 15, 1985
    Date of Patent: July 14, 1987
    Inventor: William Shell
  • Patent number: 4616658
    Abstract: A safe and inexpensive method of measuring blood flow in experimental animals using non-radioactively labeled microspheres is provided. The microspheres may be comprised of a variety of materials, including latex and agarose, and may be labeled with colored dyes or by linkage to enzymes, plant enzymes being preferred because they do not occur naturally in an animal's system. After injection and circulation of the microspheres throughout the animal's system, blood flow to particular tissue may be measured by counting the number of microspheres in the tissue sample, the initial number of microspheres in the animal's blood stream having been measured shortly after injection. In the case of microspheres labeled with colored dyes, the spheres may be counted in tissue either after separation from the tissue or while still trapped in the tissue's capillaries. Techniques for separating the microspheres from blood and tissue are also provided.
    Type: Grant
    Filed: February 27, 1985
    Date of Patent: October 14, 1986
    Inventors: William Shell, Jackie R. See