Patents by Inventor William T. Makooi-Morehead

William T. Makooi-Morehead has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants
    Patent number: 6555133
    Abstract: The present invention provides improved oral dosage form formulations of efavirenz that are useful in the inhibition of human immunodeficiency virus (HIV), the prevention or treatment of infection by HIV, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). In particular, the present invention relates to compressed tablets or capsules comprising efavirenz that contain one or more disintegrants that enhance the dissolution rate of the efavirenz in the gastrointestinal tract thereby improving the rate and extent of absorption of efavirenz in the body. The present invention also relates to the process of making such tablets or capsules.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: April 29, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: William T. Makooi-Morehead, John D. Buehler, Brian R. Landmann
  • Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants
    Publication number: 20010012518
    Abstract: The present invention provides improved oral dosage form formulations of efavirenz that are useful in the inhibition of human immunodeficiency virus (HIV), the prevention or treatment of infection by HIV, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). In particular, the present invention relates to compressed tablets or capsules comprising efavirenz that contain one or more disintegrants that enhance the dissolution rate of the efavirenz in the gastrointestinal tract thereby improving the rate and extent of absorption of efavirenz in the body. The present invention also relates to the process of making such tablets or capsules.
    Type: Application
    Filed: April 2, 2001
    Publication date: August 9, 2001
    Inventors: William T. Makooi-Morehead, John D. Buehler, Brian R. Landmann
  • Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants
    Patent number: 6238695
    Abstract: The present invention provides improved oral dosage form formulations of efavirenz that are useful in the inhibition of human immunodeficiency virus (HIV), the prevention or treatment of infection by HIV, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). In particular, the present invention relates to compressed tablets or capsules comprising efavirenz that contain one or more disintegrants that enhance the dissolution rate of the efavirenz in the gastrointestinal tract thereby improving the rate and extent of absorption of efavirenz in the body. The present invention also relates to the process of making such tablets or capsules.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: May 29, 2001
    Assignee: DuPont Pharmaceuticals Company
    Inventors: William T. Makooi-Morehead, John D. Buehler, Brian R. Landmann